Biohacking comprises diverse methods aimed at self-optimization, often grouped by nutrition, physical activity, supplementation, medical screening, mental health, and more experimental approaches.

Nutrition:

Intermittent fasting (IF) is prominent, with some animal and early human studies suggesting possible benefits for weight loss, metabolic health, and lower inflammation.

However, large analyses and public health agencies report that benefits of IF are inconsistent and no greater than general calorie restriction in most healthy adults.

Adverse effects include fatigue, mood disturbances, binge eating, and insomnia.

IF is not recommended for children, adolescents, pregnant or lactating women, those with low BMI, or a history of eating disorders; dangerous complications requiring hospitalization have occurred when unsupervised .

The ketogenic (keto) and similar low-carb diets show modest short-term weight loss but carry potential long-term cardiovascular risks: a large cohort study found increased risk of heart disease, stroke, and cancer death in high-fat, low-carb diet adherents.

Common side effects are headaches, constipation, and lethargy; these diets are not advised for individuals with diabetes or relevant organ disease and should be adopted only after comprehensive medical evaluation .

Physical Activity/Recovery:

Extreme exercise and cold exposure (i.e., ice baths) are promoted for “metabolic boosts” and reduced inflammation.

While regular moderate-intensity exercise is strongly supported for overall health, evidence for ice baths’ long-term benefit is mixed, with some studies showing minor reductions in muscle soreness but risk of hypothermia and cardiac complications for extreme protocols.

Supplements/Nootropics:

Many biohackers use large numbers of supplements, including nootropics.

Clinical support for cognitive benefits in healthy individuals is very limited, while risks include headaches, addiction, anxiety, withdrawn, and rare severe side effects.

Biohacking comprises diverse methods aimed at self-optimization, often grouped by nutrition, physical activity, supplementation, medical screening, mental health, and more experimental approaches.

Title:

Content: Tuesday, November 28, 2023

Anticipated health and wellness trends for 2024

Dance is a form of exercise, self-expression and healing. Picture: Pexels Yan Krukau

Published 2h ago

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“As people prioritise health and wellness - be it physical or mental - we are seeing a need for spaces that tick these boxes.

“Ultimately they are becoming a home of sorts, and a meeting place for like-minded people who are on a journey seeking betterment,” said Robyn Schaffner from the Light House, a new holistic haven in Cape Town.

Schaffner shares her thoughts on what the wellness trends will be for 2024.

Biophilia exercises: communing with nature

There is a growing inclination for outdoor exercise. With this in mind, studios globally will feature a biophilic design that seamlessly integrates the indoors with the outdoors, allowing fresh air to permeate during temperate weather.

Pools - previously only a space to swim laps - are now becoming a hub for innovative experiences such as Watsu water healing, cold plunging, and water breathwork.

Dance as exercise, movement, and healing

Dance is a form of exercise, self-expression, and healing globally and this will be visible at Light House too. “By embracing the trend of free-form movement, we champion ecstatic dance as a conduit for releasing energy, achieving emotional catharsis, and reconnecting with the body's innate wisdom.

“By promoting ecstatic dance, we shine a spotlight on its profound potential for holistic healing and personal transformation.”

Free movement: redefining exercise

In the realm of fitness, Light House embraces a back-to-basics philosophy with a twist.

“Celebrating the essence of free movement, our classes encourage participants to connect with their bodies on a deeply intuitive level,” explained Schaffner.

“The unique ‘Akasha’ class, blending Vinyasa flow, dance, and personal exploration, exemplifies this philosophy.

“Additionally, ecstatic dance and power and balance yoga sessions provide opportunities for uninhibited self-expression and playful engagement. It’s a matter of embracing movement in your own personal style.”

Bio-hacking: elevating wellbeing

The pursuit of optimal wellbeing remains a steadfast trend which is being explored through the lens of bio-hacking.

“By hosting enlightening talks and workshops with industry experts, delving into diverse well-being subjects, we are arming our clients with the information they need to improve their health.

“This includes an exploration of the intersection between spirituality and science, presenting a comprehensive perspective on holistic living.

“Workshops on topics ranging from mushroom stacking and sleep syncing to meditation and intermittent fasting will be offered,” said Schaffner.

Cacao: wellness in every sip

Recognising cacao’s potential as an alternative to coffee, it is the ideal companion for those seeking sustained energy, focus and tranquillity.

In the realm of beverages, cacao is fast replacing the likes of flat whites and cortados thanks to its myriad of health benefits.

Need for mental and physical clarity: supplements abound.

Nootropics, adaptogens, and functional medicines will take centre stage in 2024.

These meticulously crafted supplements are designed to support mental and physical wellbeing, fostering a harmonious balance that empowers individuals to navigate the challenges of modern life with enhanced clarity and vigour.

Nutrition:

Title:

Content: What danger can popular diets carry: the benefits and harm to health, how to properly apply
We tell you what the harm of severe restrictions in nutrition.
Why is there no universal diet?
Video of the day
The fact is that diets are built on the introduction of some products, the rejection of others or on the reduction of the diet as a whole.
Nutrition should be based on the nutritional deficiencies and surpluses of a particular person, as well as his characteristics.
For example, someone who has serious liver problems is contraindicated in a protein diet.
It can cause tremendous harm to physical health and become life-threatening.
By the same principle, other diets harm the mental and physical health of a person, sick and healthy organs, as well as general well-being.
Harmful effects can occur due to improper “entry ” into the diet.
For example, too abrupt refusal of certain products, the need to follow certain rules - all this is a great stress for the body.
Therefore, every piece of food that enters the stomach is deposited in fat, and weight is gained at the same rate as it was shed.
Thus, the diet is a very dangerous and individual diet, which can be prescribed only after passing tests to a dietitian and other doctors.
What Happens to Your Body During Diets
When we arbitrarily go on a diet without training and recommendations of specialists, the level of cortisol in the blood sharply increases, since the body is not ready for rapid changes in nutrition.
Cortisol is a hormone that destroys proteins, increases glucose levels and promotes the formation of new adipose tissue.
It is produced in response to emergency situations that occur with the body, including starvation and stress.
This hormone literally fights against our desire to sit on a diet.
The body should be ready for unforeseen circumstances, and it should not be blamed for the accumulation of reserves “for a rainy day ”.
Nevertheless, we do not need glucose and fat reserves - our desires run counter to the processes of self-preservation of the body.
On low-calorie diets, metabolism slows down, the body multiplies the lost calories at the first opportunity.
If a person has health problems, diets often increase them.
Harm of intermittent fasting
At the heart of the diet interval fasting (fasting) is the work, awarded the Nobel Prize in medicine and physiology.
In 2016, Japanese Yoshinori Osumi received an award for the discovery of the mechanisms of autophagy (the process of processing by a cell of its own components).
At the same time, there are no unequivocal scientifically proven advantages in diet-schemes of interval fasting.
Among the adverse effects are most common: fatigue, insomnia, nausea and headache.
In some people, these symptoms are temporary and appear only in the adaptive period, and someone notes them as permanent.
Interval fasting can cause irreparable harm to the health of a person who has a sick liver, diabetes, thyroid disease, gastrointestinal disease (even gastritis).
The list of contraindications is so wide that we can draw a confident conclusion that the number of people for whose health it will be useful is incredibly small, and it is not worth the risk here.
The harm of ketodiet
Keto diet is a diet plan for weight loss.
The main principle is the consumption of products with a minimum amount of carbohydrates.
The norm of carbohydrates on the keto diet is 10%.
If you turn to, you can see in the recommendations information about the rate of carbohydrate intake, which is 45-65% in order for a person to be healthy, full of strength during the day and not experience physical ailments.
Why does the body need carbohydrates?
Carbohydrates are a key source of energy in the human body, with just one gram accounting for four calories of energy.
When carbohydrates are broken down, glucose is formed in the body, it is extremely important for the preservation of tissue protein, fat metabolism and nutrition of the central nervous system.
What happens when there are not enough carbohydrates in the body?
The minimum reaction of the body that is experienced on the ketodium: weakness, apathy, headaches, constipation, bad breath.
What are the dangers of the keto diet for human health in a global sense?
In 2018, Polish professor Maciej Banach presented a report on the dangers of low-carbohydrate diets at the Congress of the European Society of Cardiology.
Studies showed that in a control group of 24,000 participants, the risk of dying from heart disease, stroke and oncology was 50%, 51% and 35% higher among those who followed a high-fat, low-carb diet.
Also for ketodiet there is a huge list of contraindications for health, that is, to adhere to it, you need to go through a full check-up of the body from a doctor.
Harm of protein diet
The essence of the protein diet is that it is necessary to exclude completely simple carbohydrates, proteins should make up 60% of the daily diet, fats (exclusively vegetable) are present in a minimum amount.
Proteins (proteins) are vital for humans.
They make up the bulk of the dense substances of the muscles, supporting tissues and protective formations (hair, nails).
They consist of immune bodies that protect the body from infections.
The body does not know how to accumulate proteins, so a person must constantly eat protein food.
But for the normal functioning of all systems and organs, fats and carbohydrates are no less necessary.
Undergetting vital substances with food, the body is faced with their deficiency.
Trying to make up for the missing carbohydrates, a person first spends their own reserves (glycogen) accumulated in the muscles and liver.
Then the deferred fat reserves are spent.
The harm of a carbohydrate-free diet
The difference between a carbohydrate-free diet and a keto-diet is in the amount of daily carbohydrates consumed.
The harm of carbohydrate-free and keto-diet is approximately the same, since the principle of their work and construction is similar to each other.
The main danger - the risk of cardiovascular diseases increases.
If you have kidney problems: pyelonephritis, urolithiasis, have had injuries or have a hereditary predisposition to their disease, eating too much protein creates an additional burden on the organs.
This can worsen kidney function: chronic pathologies may worsen.
An unbalanced diet with a deficiency of carbohydrates can provoke osteoporosis and the formation of kidney stones.
As well as a decrease in blood glucose levels, which is especially dangerous for people with diabetes, prediabetes or some metabolic disorders.
Even healthy people against this background feel irritability, aggression and weakness, malaise.
This is especially important if you play sports, work hard and you need concentration and attention, sufficient physical strength.
Championship.com: top news

Intermittent fasting (IF) is prominent, with some animal and early human studies suggesting possible benefits for weight loss, metabolic health, and lower inflammation.

Title:

Content: Scientists Reveal the Benefits of Intermittent Fasting
HEALTH
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American scientists have discovered that intermittent fasting, which is now widespread, has many health benefits, in addition to weight loss.
According to Cell Reports, a diet that restricts eating at certain hours is of interest to people seeking to reduce and control their weight, so most previous studies focus on this issue.
But scientists at the Salk Institute for Biological Research in California decided to conduct experiments on laboratory mice to determine the effect of intermittent fasting on body functions.
The results of these experiments have shown that intermittent fasting helps with type 2 diabetes, fatty liver disease, liver cancer and even infectious diseases, including COVID-19.
Prof Satchidananda Banda, head of the research team, said: "The main result of the clinical tests is weight reduction.
"But we have discovered that intermittent fasting is beneficial not only for metabolic diseases, but also for increasing insulin resistance and resistance to infectious diseases."
According to him, glucose intolerance, the first step of nonalcoholic fatty liver disease and liver cancer, is one of the few cancers whose incidence and mortality have risen, rather than declined over the past 25-30 years.
This trend makes the search for simple ways to combat glucose intolerance a major scientific research priority.
The experiments involved feeding the mice with foods rich in fat and sugar, but for nine hours a day they were deprived of food.
The researchers coordinated the eating schedules with the mice ’ s lifestyle – sleeping during the day and looking for food at night.
During these experiments, the researchers were conducting an analysis of the chemical composition of the liver and the level of glucose in the blood, assessing muscle mass and testing performance, endurance and survival in case of sepsis.
The researchers discovered that intermittent fasting protects against fatty liver disease regardless of age and gender.
Glucose tolerance tests performed on mice after 16 hours of fasting showed that intermittent fasting keeps blood sugar levels low and provides a quicker return to normal after disturbances.
Intermittent fasting, therefore, can be a free and convenient way to prevent or treat diabetes and metabolic syndrome.
The researchers also found that intermittent fasting can protect against death from sepsis, for example in intensive care units, which is especially important during a pandemic.
Source: Novosti
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According to the studies, how does intermittent fasting help?

It reduces the risk of lifestyle-related diseases, such as metabolic disorders.

However, large analyses and public health agencies report that benefits of IF are inconsistent and no greater than general calorie restriction in most healthy adults.

Title:

Content: Is fasting good for your health or dangerous?

#fasting #good #health #dangerous

On social networks, “therapeutic” fasting is on the rise. A juicy business which can, however, involve risks.

You may have heard, in your family or friends, of someone trying “intermittent fasting”. The principle is simple: by stopping eating, we would help the body to “purify” itself. But in reality, this very poorly regulated practice can quickly go off the rails, as proven by the death of a woman in Indre-et-Loir in 2021.

The naturopath who supervised this fasting course, a former salesman, was indicted on January 12, 2023. For several years, he has been selling these expensive services (more than 3,000 euros for a month) consisting of depriving oneself of food for a period of time. week or more. The man claims that fasting can work miracles: “A disease that cannot be cured by fasting cannot be cured by anything else“, it was written on his site.

These fasting cures are commonplace in France and the authorities are only beginning to be alerted. In 2021, the Interministerial Mission for Vigilance and the Fight against Sectarian Abuses (Miviludes), urged caution: “Whatever their name, they have in common that they are expensive and encourage the isolation of trainees, thus constituting a means for their promoters to establish real control over them.

In a report published in 2014, the National Institute of Health and Medical Research (Inserm) also recalled that“no clinical data based on rigorous methodological trials can currently support the merits of this approach, which therefore remains essentially theoretical for the moment.”

Eight years later, it is clear that science has still not resolved the question. Which does not prevent the practice from having the wind in its sails, particularly among young people.

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Some internet stars have taken up the subject to fuel their careers, like comedian Swann Périssé (608,000 subscribers) who spent an entire week without eating. The video is presented as a promotional operation in partnership with Chemin des Possibles, a company organizing “fasting/detox” courses in France and Morocco.

Less strict but just as fashionable, intermittent fasting is also popular among “fitness” or “lifestyle” influencers. The objective: to eat in a shorter time slot during the day by extending the nighttime fast.

To this too, we attribute all kinds of benefits like the “weightloss“, the “purging the body“, the “increased insulin“, and “well-being“, and even “improved cognitive abilities“.

Some companies have also sensed the right opportunity. With one in two adults overweight or obese in France, weight loss is a growing market. Lithuanian company Kilo Health has launched its own paid mobile application, DoFasting, specializing in intermittent fasting.

Thanks to the partnership system, Kilo Health can count on influencers – mainly followed by a young audience – to promote its application.

On its site, DoFasting promises you a “ fast track to healthy weight loss“and swear that” intermittent fasting is a safe and effective way to get in shape and improve your overall health“.

In just a few clicks, it also guarantees miraculous results: a loss of ten kilos in two months for a man of 1m75 and 85kg! All that remains is to pay 66 euros for six months of subscription (or 33 euros for one month) to refine your silhouette. Safe ? Not so sure.

In just a few clicks, the application promises a weight loss of ten kilos in just two months thanks to intermittent fasting. • © Screenshot of the DoFasting application website

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Professor David Jacobi is a doctor and researcher at the Nantes Thorax Institute (Nantes University, Nantes University Hospital, Inserm, CNRS). He is one of the leading experts on the subject of intermittent fasting: ” There are claims regarding intermittent fasting that exceed the level of available evidence“.

On the question of the link between intermittent fasting and weight loss, science has in reality still not decided: “When we talk about human studies, there aren’t many and the level of evidence is low“, continues David Jacobi. To the extent that the burden of proof falls on the defenders of fasting, the arguments in their favor are therefore very thin.

When we talk about weight loss and weight management, it’s easy to grasp solutions that seem miraculous. It’s been around for a long time.”

David Jacobi, doctor and researcher at the Thorax Institute

Ces “evidence available“, the doctor presents some of them in a conference broadcast on YouTube. The expert cites two, as examples. The first, published in 2015, concludes that 8 people lost 3.5 kilos in sixteen weeks. men suffering from obesity. Another, more recent (2020) and on a larger number of patients, concludes the opposite: fasting did not allow weight loss.

In the majority of studies looking at weight loss, people did not lose significant weight. There were no additional benefits to dietary restriction.

David Jacobi, physician researcher at the Thorax Institute

Still, not everything has to be thrown away: “LThe general idea of intermittent fasting is to eat over a slightly more natural period, which corresponds more to our internal rhythms. It has a certain coherence“, recognizes David Jacobi.

This can be part of a balanced diet intervention, especially if your eating times are very disrupted.

David Jacobi, physician researcher at the Thorax Institute

Benefits of intermittent fasting on metabolism may therefore exist. But, again, without scientific certainty: “We have some studies, on a very limited sample of people, which show interesting effects“, continues the specialist.

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For example, a recent study, published in 2020, shows a drop in LDL-cholesterol (the “bad”), a drop in sugar levels or even an improvement in the quality of sleep in the patients studied.

Except that the study only concerns prediabetic adults in their sixties. From what general conclusions can we draw? “We must not attribute to studies effects that they have not demonstrated“, insists the doctor. Not everyone is a prediabetic adult in their 60s. So we cannot attribute this type of beneficial effect to everyone.

There remains one last unanswered question: how to obtain information to avoid erroneous or misleading advice? “Its pretty hard“, recognizes David Jacobi. “If you choose the studies whose results suit you, you will find some.”

However, the health benefits of fasting are, for the moment, purely theoretical: “The public health messages that can be established regarding certain health benefits of diet are based on multiple well-conducted studies: their method is correct and their results point in the same direction. That’s when we can say, with some confidence, that the intervention is good for our health.”

Or, “we are not there with fasting, even if the results obtained encourage continued research.” Among some of our neighbors, on the other hand, the practice of fasting is commonplace and can even be reimbursed by social security. This is the case for example in Germany where medical centers are specially dedicated to fasting.

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Adverse effects include fatigue, mood disturbances, binge eating, and insomnia.

What are the risks and dangers of combining the keto diet and intermittent fasting?

What are the risks and dangers of diets?

IF is not recommended for children, adolescents, pregnant or lactating women, those with low BMI, or a history of eating disorders; dangerous complications requiring hospitalization have occurred when unsupervised .

The ketogenic (keto) and similar low-carb diets show modest short-term weight loss but carry potential long-term cardiovascular risks: a large cohort study found increased risk of heart disease, stroke, and cancer death in high-fat, low-carb diet adherents.

What are the risks and dangers of adhering to the keto diet for a long period of time?

negative impact on heart and kidney function

Common side effects are headaches, constipation, and lethargy; these diets are not advised for individuals with diabetes or relevant organ disease and should be adopted only after comprehensive medical evaluation .

Physical Activity/Recovery:

Title:

Content: Home » biohacking, reprogramming mind and body to live better

biohacking, reprogramming mind and body to live better

by admin

It’s called “biohacking” and it comes from Silicon Valley. Listen: The long life diet: the longevity formula is calorie restriction …

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It’s called “biohacking” and comes from Silicon Valley.

A relatively new word that comes from the union of “biology” and “hacker” and indicates the attempt to positively influence the functioning of the organism, by hacking, ie trying to “force”, one’s genetic heritage. A strategy to live better and longer launched years ago by Californian top managers and which then spread throughout the world. How to upgrade the “operating system” of the human body? No manipulation, here we are talking about “reprogramming” and new lifestyles. “Our genetic heritage has enormous unexpressed potential that can be activated,” he explains Fabio Piccinidoctor and psychoanalyst, researcher of Food Sciences of theMarche Polytechnic University, author of the book “Biohacking Techniques: how to optimize metabolism to increase health and longevity”. “Biohacking aims to activate epigenetic modifications by awakening dormant genes to enhance the body’s resources.” While genetics studies the structure of DNA, epigenetics the way genes express themselves, i.e. how much they are turned on or off. “We’re talking about a set of strategies that aim to strengthen the body from a physical and mental point of view, first of all through nutrition, sleep quality, physical activity, cognitive stimulation”. One of the pillars of biohacking and the intermittent fasting, Piccini adds, which plans to concentrate the diet in a precise time span of the day (to be followed always under medical supervision). «But it is equally important to take care of sleep, we know very well that sleep debt accelerates aging and that 30-40 percent of people sleep too little. Just as it is essential to check thehydration. Physical training must also be intermittent, with recovery periods in place to allow the muscle layers to rebuild. And then, you have to keep learning something at any age, another pillar of biohacking: studying music or a new language, for example, to counteract cognitive degeneration”.

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THE QUALITY OF LIFE

Sandra Milo is one of the supporters of this well-being and longevity strategy. «I’m lucky, at 90 I’m in full health and I still have a great desire to enjoy life. I don’t know if it’s a matter of genetics, nor do I think there is a “magic formula” of longevity, but I have certainly always been careful to lead a healthy life. There is nothing more beautiful than reaching old age with a smile and in full autonomy », says the actress who baptized the first Biohacking Suite in Rome. “Our mission is not so much to lengthen life but to improve its quality by lowering the rate of morbidity,” explains Dr. Claudio Urbani, specialist in regenerative medicine, neuroscience and stress therapy, head of the longevity center Umb. «Biohacking aims to modify dormant functional responses from non-use, from muscular or cardiovascular function to flexibility. It is about regaining possession of the body and the mind-body axis, starting with stress management». Diagnosing your own state of “aging” involves a series of tests. «The measurement of oxidative stress which measures the quantity of free radicals and indicates any inflammatory states, plethysmography to evaluate the functionality of the microcirculation of the legs, impedancemetry to study body composition, fat and lean mass, nutritional status and hydration level. And only after the check is a tailor-made program created for each person. Among the suggested therapies, there is also that of the cold which stimulates the metabolism and reduces inflammation ».

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Extreme exercise and cold exposure (i.e., ice baths) are promoted for “metabolic boosts” and reduced inflammation.

While regular moderate-intensity exercise is strongly supported for overall health, evidence for ice baths’ long-term benefit is mixed, with some studies showing minor reductions in muscle soreness but risk of hypothermia and cardiac complications for extreme protocols.

Supplements/Nootropics:

Title:

Content: New superhuman brains.
About drugs that make you smarter and more miserable!
Entrepreneur and programmer Dave Asbury ’ s mornings may not seem different at first glance than anyone else ’ s.
Dave wakes up and takes his young children to school, then comes home and makes himself a breakfast of coffee and butter.
Then, he walks into his office, reaches out to a corner, pulls several capsules out of boxes that look like medicine, and then starts working.
[1] Here it is.
Everything is normal, until we discover that the capsules he takes are not really drugs, but drugs.
Dave ’ s use of these drugs cannot be considered strange: throughout human history, before civilizations even existed, drugs accompanied humans.
For the damage that may lead the individual to death, some found in them an escape from the worries and burdens of life, although the price they will pay for this is high.
What is really strange is that what Dave, and many others, want from taking a certain type of drug is the complete opposite of all this; he doesn ’ t want to get away with it every morning; he wants to indulge more in it and manipulate it to his advantage; he wants to become smarter, more productive, richer.
Dave ’ s drugs are neither weed nor opioid, nor are they similar to any other familiar drug, Dave taking nootropics, or “smart ” drugs.
The chemist C.C. didn't have a clue.
Giragia Yuma said that the word he invented as the name for the drug Pristam, which he installed in his laboratory one day in 1964, would become so popular 60 years later.
The name of this compound came from the combination of the Greek words "nos", which means brain, and "tropin", which means "me," and created in his laboratory the first drug that he hopes will succeed in bending the brain of those who use it.
[2] Like any medicine.
Another, Gergea designed the prestam as a treatment, and he hoped it would help patients with brain and cognitive disorders, such as Alzheimer ’ s in the elderly and speech disorders in children.
But most Nutrobix users now are often completely healthy individuals with no brain abnormality, and do not aim to cure themselves of a disease.
[3]
Smart drug users are also different from any other type of drug users: they are not marginalized groups or young Magna people who dose drugs in dark dens or raucous parties; nootropics are some of the world ’ s finest college students and some of the brightest tech minds in Silicon Valley, the tech heartland of San Francisco.
By taking drugs that are mostly made for people with cognitive disorders as a result of mental illness, these brilliant students and programmers want to enhance their ability to learn, focus and think creatively to become smarter, which seems to be happening under the influence of these drugs.
Phoebe, a history student at a prestigious university in England, describes the impact of nootropics on her in an interview with The Guardian: “These drugs help you work, so you can study longer without distractions.
You feel like going to the library on your own, and you don ’ t even want to take a lunch break.
You look at the clock and it ’ s 7: 00 p.m., but you can still keep going. ”
Johnny, a student at the same university, describes his first experience with drugs: "I had a strange feeling, I remember sitting in the exam and thinking, 'This is terrible!
Oh, my God!
I feel as if I ’ m going to lose consciousness, ” but at the same time I could remember everything, whole paragraphs remembered word for word.
That was great. "[4]
It all sounds really cool, taking a few pills in the morning gives you an incredible ability to work and think.
But, as anyone who has ever taken a drug knows, every drug has side effects that range in severity, from mild things like a headache to symptoms as severe as the disease for which you took it, and additional drugs have to be taken to treat it.
So what are the side effects of entropy?
There aren ’ t enough studies to answer this question, but many people ’ s long-term experience with Nutrobox has never been promising.
Writer and journalist Kate Miller tells her story with those drugs that she started taking after a student in her final year of university, continuing with her after entering her career.
At first, everything seemed great, she found that she could concentrate for long hours and work tirelessly until late at night, and with all this, she was able to maintain a good social life.
But not long after, the ugly face of Nootropics revealed itself to her: Kate became an addict.
In her New York Times article, Kate recounts what she went through: “I was fooling myself when I thought I could stay balanced while taking these drugs, when I thought the benefits outweighed the harm.
I started to increase the doses I was taking, and then, I found myself spending long nights flipping over in bed and falling asleep, my mind racing and my heart beating violently.
When I woke up the next morning, the first thing I did was reach out to take the pills again.
My body started getting used to these drugs, and then I lost their effect, so I started to increase the dose.
I would take it if I found myself yawning after I turned off the alarm.
I turned into a wreck, always angry and lost my ability to connect with the world. ”
Kate reached the point where she found her life was falling apart on all levels, and here came her decision to stop taking those drugs once and for all.
But what no one has told her is that stopping itself will be difficult, as nitrobix, like other drugs, leaves its users at the beginning of quitting defenseless in front of a barrage of painful withdrawal symptoms.
“I found myself sleeping during meetings and I couldn ’ t finish my work before the deadline.
I also began to feel very hungry and began to eat heavily.
This disorder left me with a very fragile and sensitive brain chemistry, and my weight gain and late work only made matters worse.
It was hard for me to understand at the time that what I was going through was withdrawal symptoms; no one had warned me about the side effects of these drugs. ”
Phoebe and Jonny, students who had been helped by Nootropics during the exam period, soon noticed the bad effect on them; Phoebe began to feel severe pain in her stomach, and Jimmy felt that he was becoming too dependent on her for everything, and he ate it every morning without really needing it.
Fortunately, before they went through Kate ’ s bad experience, the Taliban gave up Nutropics altogether.
Even Dave Asbury, an entrepreneur who takes huge amounts of nootropics every morning and founded a company that makes coffee mixed with the drugs, has developed a severe allergy to certain foods that he has been eating normally throughout his life.
In a paper in the journal Clinical Neuroscience, researchers Farid Taleh and Jane Aglotti found that many Nutrobix drugs cause side effects ranging in severity from diarrhea, headaches, dizziness and insomnia, to memory loss, identity disorders and motor system deficiencies.
The research also included a case study of four individuals between the ages of 17 and 28 who were taken to the hospital emergency room after a nervous breakdown. [6] Here, we find ourselves faced with a more important question: Why would people with high levels of intelligence resort to drugs that may add to their intelligence even deeper, but they may also have side effects that no one knows are serious?
[7]
Tim Farris, an entrepreneur and renowned author of human development books, has no real qualms about the long-term side effects of nootropics.
Speaking to CNN, after he started talking about the amount of pressure entrepreneurs are under today, he concluded: “Just like an Olympian who is willing to do anything, even if he reduces his age to five years, to win a gold medal, you ’ ll think about any drugs you take to become smarter. ”
[8]
Jeff Wu, a software engineer who set up a company that specializes in manufacturing nootropics, goes on to say, “Creativity and high mental performance are the only ways you can succeed in Silicon Valley.
I liken tech and finance to professional athletes, so the only way for your team, product or project to be successful is to have a comparative advantage over competitors. ”
It ’ s not just the tech industry, Wu adds: “To become smarter and more productive is to meet modern day standards of success. ”
If some people seem willing to swallow poorly researched drugs without suffering from a real disease just to increase their ability to produce something strange, you ’ ve never heard of the term and the practices that these drugs and many other strange practices include: body hacking, or “biohacking. ”
As a programmer or engineer might look at a computer looking for ways to develop it, biohackers are trying through methods that vary in extremes, from intermittent fasting to injecting themselves with stem cells, to make their bodies and brains better, stronger, healthier.
At first glance, this may not seem like a bad thing, so who wouldn ’ t want to be the best possible version of themselves?
But what ’ s interesting about this is that their desire to develop their bodies and brains stops at the point where these bodies and brains are more productive, and does not go beyond them to other areas of life, where none of the body hackers, for example, thought about creating a drug that by taking it more willing to help others in their distress.
Faced with the large number of people who are willing to take Nutropics to increase their production capacity, neuroscientist Anders Sandberg found in a study that only 9% of people are willing to take a drug that makes them more empathetic or kinder.
This increased use of nootropics and the willingness to manipulate the very composition of the body in order to increase production is itself a symptom of a civilizational disease that envelops our world today: the obsession with success at any cost.
The Guardian ’ s Carol Gadwallar says of this: “In the 1960s, sedatives were known as the little helper of mothers.
Today, however, Futropics is a small aid to capitalism.
“It ’ s just another symptom of a world dominated by competition where everyone is looking for a comparative advantage that puts them above others. ”
[10] Neuroscientist Anjan Chatterjee says: "Today, from the moment of their birth until their death, people only know about running in a rat race.
We are overwhelmed by the feeling that there are a limited number of prizes on the horizon and that everyone is competing for them.
It ’ s hard and you ’ re willing to do anything to win. ”
[11]
In this world governed by machines and numbers, we are also expected to become machines: machines that wake up in the morning and work tirelessly until evening falls, and everything is ultimately governed by numbers.
How successful you are depends on how much you produce each day, which at the end of the month will translate into how much you make.
Your salary or wealth is no longer just a means to provide you with a decent life, but has become a kind of obsession, everyone wants to be successful in a modern culture that values only material values, and defies those who fail the test of making money.
In such a culture, it is not surprising to find people willing to swallow drugs with unknown side effects in order to be better.
Isn ’ t that, in one way or another, what modern culture imposes on us all today, working to burn and losing some of life ’ s simplest pleasures just to live properly and escape the stigma of failure?
The question remains: Is there then a relentless pursuit of success, what kind of happiness?
Or is the summit nothing more than a glittering image of something really empty and cold and lonely?
_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _
Sources:
1.
I ’ m The Guy Who Created Bulletproof Coffee – This Is My Morning Routine
2.
Nootropic
3.
Under pressure, Silicon Valley workers turn to LSD microdosing
4.
Students used to take drugs to get high.
Now they take them to get higher grades
5.
The Last All-Nighter
6.
Probable Nootropicinduced Psychiatric Adverse Effects: A Series of Four Cases
7.
My smart drugs nightmare
8. smart drugs: what silicon valley is on
9.
Under Pressure: Silicon Valley workers turn to lsd
10.
Students used to take drugs to get high.
Now they take them to get higher grades
11.
Under Pressure: Silicon Valley workers turn to lsd
Source: The Island
About this story
“Narcissism ” is a widespread term, often misused to describe anyone who abuses us.
But in fact, a little bit of narcissism will do you good -- this report looks at the evolution of the concept of narcissism over the past decades.
6 / 10 / 2017
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Many biohackers use large numbers of supplements, including nootropics.

Clinical support for cognitive benefits in healthy individuals is very limited, while risks include headaches, addiction, anxiety, withdrawn, and rare severe side effects.


Biohacking is a loosely-defined term that describes the pursuit of self-optimization and improved health through the intentional modification of lifestyle, diet, physical activity, technology, and cognition.

The movement emphasizes personalized experimentation, aiming to enhance quality of life and reduce susceptibility to disease—sometimes with an eye toward longevity.

Biohacking in its most common forms originated in Silicon Valley as a strategy for “upgrading” the body by influencing biological processes, largely without genetic modification.

The goal is often to activate perceived “untapped” or “unexpressed” potential, leveraging epigenetic changes—changes in gene activity influenced by environment and behavior.

Core philosophies center on self-quantification, ongoing adjustment of routines, and an ethos of personal responsibility for health outcomes.

Rather than seeking shortcuts, practitioners—increasingly from diverse backgrounds—often use habit modifications, technology tracking, and diagnostic tests to guide their choices.

The field has expanded to consider women’s physiological needs (such as fertility and hormonal cycles), and there is growing recognition that biohacking should favor flexibility and personalization over rigid regimens.

Popular nutritional biohacks include strict diets intended to lower inflammation, control blood sugar, or “optimize” the gut.

Typical examples include the ketogenic (high-fat, very low-carb) diet, gluten-free and dairy-free diets, and intermittent fasting (cycling between periods of eating and fasting).

The “bulletproof” diet—a variation on ketogenic eating that favors high-quality fats, especially in the form of coffee blended with butter or oil—is also prominent.

Many biohackers additionally avoid processed foods and sugar, favoring anti-inflammatory foods like oily fish, olive oil, fermented products, and plant-based milk alternatives.

There is widespread interest in identifying food sensitivities through allergy testing.

Supplement use is common and can include collagen, glutathione, antioxidant-rich foods, and compounds like spermidine.

Physical activity-related biohacking covers regular, sometimes intense, physical exercise.

Practices include resistance training, high-intensity interval training (HIIT), and novel methods such as katsu bands (which restrict blood flow to enhance muscle adaptation) or inversion chairs for neurological stimulation.

A frequently cited intervention is cold exposure, including ice baths, which are claimed to reduce inflammation and stimulate metabolism.

Recovery is also a focal point, with adherents designing cycles of activity and rest to maximize muscle and nerve repair.

Supplementation is a central element, with many individuals taking a wide variety of vitamins, minerals, antioxidants, and compounds marketed for longevity, cognitive enhancement, or inflammation reduction.

Stacks (combinations) of supplements can include both common substances (vitamin D, omega-3s) and niche or experimental ones (such as spermidine, glutathione, or nootropics).

While some supplementation targets confirmed deficiencies or evidence-backed needs, the high intake of multiple and high-dose supplements can raise the risk of interactions, toxicity, or unknown health impacts.

Self-quantification and ongoing medical screening are fundamental to many biohackers, who regularly undergo blood testing to track markers of inflammation (such as CRP and cytokines), monitor hormone levels, or assess “biological age.”

The use of wearable devices (such as heart rate variability monitors or sleep trackers) is widespread for real-time metric tracking.

Specialized apps and wearables have emerged targeting female users, providing tailored data about hormonal cycles, fertility, and pregnancy.

Mental health and cognitive optimization are also common biohacking targets.

Practices include meditation, mindfulness, sleep tracking and improvement, and the use of “habit stacking” (building multiple health practices into daily routines).

Nootropics (substances marketed for cognitive enhancement) and, less commonly, prescription drugs like antidepressants are sometimes used, sometimes as part of self-experimentation for perceived increases in alertness, focus, or well-being.

There is a notable trend toward promoting balance and warning about mental health harms from obsessive optimization or the pursuit of perfection.

Some biohackers pursue more extreme interventions.

The “grinder” subculture experiments with technological implants or body modifications, such as chips, magnets, or sensors under the skin.

While some interventions (e.g., implantable payment chips) are relatively benign, others are unregulated and carry substantial medical risks including infections, device failure, or unintended health consequences.

Expert opinion stresses that technological body modification should proceed only under professional medical oversight.

In terms of scientific backing, a number of biohacking techniques overlap with evidence-based recommendations: regular physical activity, increased sleep quality, and anti-inflammatory dietary patterns (Mediterranean-style diets rich in fish and olive oil) are broadly supported in clinical research and associated with lower risk of chronic disease and improved longevity.

Practices like intermittent fasting have some clinical support for metabolic health and weight loss outcomes, though long-term studies, especially in those without metabolic disease, are limited.

Likewise, some specific supplements (e.g., vitamin D in cases of deficiency, omega-3 fatty acids for cardiovascular health) are supported by research.

Conversely, more extreme approaches—such as multiple restrictive diets simultaneously, very high supplement doses, use of experimental compounds, prolonged or extreme fasting, and unregulated device implantation—generally lack robust evidence from well-controlled, long-term human studies and may expose individuals to health risks.

Most risks associated with biohacking arise from extreme, unsupervised, or poorly informed practices.

These include negative effects from high or prolonged use of certain supplements (potential toxicity or interactions), nutritional deficiencies from combined elimination diets, medical emergencies due to self-experimentation (especially with technology or potent drugs), and deterioration of mental health tied to perfectionism, social isolation, or stress.

Health authorities and medical experts note that while self-quantification and some “hacks” can increase awareness and motivation, biohacking should not replace medical care or established preventive health practices.

Interventions without robust evidence should be treated with skepticism and, if pursued, closely supervised by qualified professionals.

In summary, biohacking encompasses a spectrum from evidence-aligned health habits (such as improved diet and physical activity) to extreme or speculative self-experimentation.

While some methods are grounded in research, many lack sufficient evidence, and there are real physical and psychological risks associated with extreme, rigid, or unsupervised regimens.

Open communication and involving healthcare professionals are recommended for those engaging in intensive biohacking practices.

The field’s emphasis on personalization and tracking can empower individuals, but moderation and critical evaluation of claims—to distinguish science from hype—are essential for safety and well-being.

Biohacking is a loosely-defined term that describes the pursuit of self-optimization and improved health through the intentional modification of lifestyle, diet, physical activity, technology, and cognition.

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Biohacking & Toxic Masculinity: How Women Dismantled The Boys Club

Author: Medical reviewer:
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By Jamie Schneider
Beauty & Health Editor
Jamie Schneider is the Beauty Editor at mindbodygreen. She has a B.A. in Organizational Studies and English from the University of Michigan, and her work has appeared in Coveteur, The Chill Times, and Wyld Skincare.
Medical review by
Bindiya Gandhi, M.D.
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Dr. Bindiya Gandhi is an American Board Family Medicine–certified physician who completed her family medicine training at Georgia Regents University/Medical College of Georgia.
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Take a quick search for “biohacker” on TikTok (a tag with over 137 million views), and you’ll discover a slew of men discussing their muscle gains, testosterone levels, and cold plunge routines. You’ll see some women on the page, but the space is undoubtedly dominated by male energy. And think of the outspoken biohackers you may listen to on podcasts—chances are most of them are men, too.

This gendered approach to biohacking, while pervasive, is simply misguided. But now, women are asserting their authority in health optimization, and we expect their emphasis to soar in the year ahead.

Meet the experts

Molly Maloof. M.D.

Molly Maloof. M.D. provides health optimization and personalized medicine to high-achieving entrepreneurs, investors, and technology executives. Since 2012, she has worked as an advisor or consultant to more than 50 companies in the digital health, consumer health, and biotechnology industries. Her company, Adamo Bioscience, is working on sexual health optimization.

Gabrielle Lyon, D.O.

Gabrielle Lyon, D.O. is a board-certified family physician leading a disruption in modern medicine that focuses on the largest organ in the body: skeletal muscle. With a background that includes a combined research and clinical fellowship in geriatrics and nutritional sciences at Washington University and undergraduate training in nutritional sciences at the University of Illinois, she is a subject-matter expert on protein for health, performance, aging, and disease prevention.

Stacy Salvi

Stacy Salvi is the vice president of product and strategy at the medical device company Movano Health—the creator of the Evie Ring, the first medical-grade health wearable designed for women.

Mona Vand, PharmD

Mona Vand, PharmD studied pharmacy at Massachusetts College of Pharmacy and Health Sciences before developing her platform that shares holistic wellness advice.

Why biohacking isn’t just for “bros”

“Women are the original biohackers,” declares family physician, Molly Maloof, M.D. “Our hormones change throughout our lives, and this requires us to adapt accordingly.” Our biology means that women often need to constantly edit their health routines and experiment with lifestyle habits as time goes on. Isn’t that the very definition of biohacking?

Let's back up: Here at mindbodygreen, we think of “biohacking” as the practice of making lifestyle tweaks to optimize health and promote longevity. Not shortcuts—contrary to popular belief—but low-lift, everyday habits that complement and enhance an existing well-being routine. Think: optimizing your exercise regimen using tools and techniques (the “biohacks”) to enhance muscle growth. It’s essentially all about advancing health with “do it yourself” biology—a topic that can pique anyone’s interest, regardless of gender.

“[Women] have a most complex physiological lifecycle that requires us to track and manage fertility, pregnancy, breastfeeding, sexuality, perimenopause, and menopause. So we should be looking at biohacking as a path to even greater health and owning the opportunity to improve our lives,” says Maloof.

Yet many women feel intimidated to enter the biohacking scene as it exists today, turned off by the male-dominated energy in the room.

Women are the original biohackers

Molly Maloof, M.D

“Biohacking has always grabbed my attention, and I want to learn, but it sometimes makes me really stressed out, because I go into this state of perfectionism where I have to do all the things,” says doctor of pharmacy and wellness practitioner Mona Vand, PharmD. “The few biohackers that I followed were all males… it just doesn't really resonate with my energy.”

This male energy is not only frustrating but can potentially harm women’s health in the long run. After all, building muscle, prioritizing protein, and keeping an eye on various health metrics are crucial for longevity—in some cases, these proactive measures can save lives. When women don’t get involved, it can totally impact their well-being.

“Physical strength is nonnegotiable,” says functional medicine doctor Gabrielle Lyon, D.O. “I've been a physician since 2006, and I've never heard someone say, ‘I regret being physically strong.’” And the muscle-building space impacts more than just physiological changes, she says. “You optimize fertility, you make healthier babies, you help the epigenetics of your child,” Lyon adds. “You age better, your skin is better, you're less likely to fall and break a hip… There's nothing that doesn't get better the stronger you are.”

So let’s be clear: Dismantling the biohacking boy’s club is not just about helping women feel included; there are real health implications at stake here.

Why the biohacker space actually really needs a dose of feminine energy

I’d be remiss not to mention how biohacking culture can easily become synonymous with hustle culture (some experts don’t even like to use the term, as it implies you can achieve optimal health with quick fixes). But as more women enter the biohacking space, we expect it to become more intuitive and less about hitting every single benchmark. From there, we predict women will focus more on sustainable changes long-term instead of a gazillion quick hacks.

“I used to think it was a flex to do a million things at the same time and habit stack,” Vand recounts. “I now carve out time for doing things that have no efficiency to them, that are strictly for joy or rest and relaxation, versus benefiting my longevity or health. It can be a little bit obsessive when you get into this thought pattern, and I just don't resonate with it.”

This doesn’t mean biohacking will become “softer” as it embraces feminine energy. But there’s an opportunity here for women to introduce some much-needed flexibility into a space that has long felt needlessly rigid.

How the biohacker game is changing — and where it’s headed next

Thanks to a growing awareness that healthcare protocols should not be gendered, more women are now starting to pay attention to markers of performance like lean muscle, hormetic stressors, VO2 max, HRV, zone 2 training, etc. “Cold plunging, saunas, and harder, more physical activities are not just for the boys anymore,” adds Lyon—and we expect an even bigger shift to come in 2024.

“I think it’s super exciting to see biohacking become more mainstream and more women joining the conversation,” adds Maloof. She praises apps like Wild.AI, for women who aim to make lifestyle adjustments based on their menstrual cycle, and Zero, for women who want to dabble in time-restricted eating, both of which have helped to herald the shift.

Other existing health optimization companies are now inviting women into the conversation by introducing specific features informed by their unique physiology. WHOOP, for example, is currently working on upgrades to their popular health-tracking band: “We did a study recently where we learned a lot about how a woman's body changes during pregnancy and how her heart rate variability (HRV) will evolve. It'll decrease, and then about seven weeks before she gives birth, it will increase sharply,” explains Will Ahmed, WHOOP founder and CEO, on the mindbodygreen podcast

If a woman didn’t know that this was supposed to happen, she might look at this stark increase with a critical (or anxious) eye. “We've been able to take population-level data on pregnant women and now have a feature in the app, where a woman can see how her body is evolving alongside what other pregnant women are experiencing,” he adds.

Similarly, creatine supplements—from the ingredients to the packaging—are no longer marketed toward dudes looking to bulk up, and we are certainly here for it. After all, muscle mass is a predictor of longevity and healthspan, so supplements that promote it can help all of us “hack” our health in a big way.

And as Lyon notes, women have lower endogenous creatine stores compared to men (meaning, they have less available). And the amino acid has been associated with significantly increased muscle mass1 in both men and women, without increasing the risk of adverse outcomes2, like weight gain. “Most of the women in my practice will go on creatine, and they find anecdotally that it really improves both anaerobic and aerobic exercise performance,” Lyon shares.

Not to mention the supplement’s brain health perks: Taking creatine has been shown to benefit both working memory and processing speed3 as well as cognitive longevity4. “It is above and beyond simply sport performance,” adds Lyon, who has certainly seen an uptick in women curious about creatine.

As women feel intimidated (or even restricted) by biohacking spaces, some experts have taken it upon themselves to create new ones that center the feminine. For example, neuropsychophysiologist Kayla Osterhoff, MPH, offers a Women's Biohacking Mini Course, consisting of lifestyle routines and tips aligned with female physiology.

Osterhoff also recently presented at the 2023 Dragonfly Live Conference—among other female biohackers—to discuss the latest advancements in women's well-being and the “health revolution” that’s sweeping the mainstream. This conference aims to gather the “who's-who” in the health space to discuss cutting-edge strategies and innovations that optimize well-being—by having women biohackers at the forefront of the conversation, we can expect them to hit the main stage in a broader sense.

Or take the brand new Evie Ring, the first medical-grade health wearable designed for women, created by medical device company Movano Health. The technology ties hormonal information to a woman’s sleep, activity, and heart health data (among other metrics).

For instance, “If we notice a more restless night of sleep in the luteal phase, we'll point it out and also give some strategies for how somebody may attack their day, despite having not gotten as good of a night of sleep,” says Stacy Salvi, vice president of product and strategy at Movano Health. Similarly, “We know that there are cardiovascular implications when your estrogen drops, so they would want to keep a better look on the function of their heart,” she adds. “This would be something that they would be able to do from our app.”

Even the design itself was made with women in mind: The ring features an open band meant to accommodate how women’s fingers change in size throughout the day, so it can stay comfortable.

To avoid needless stress, Evie also limits the amount of goals you can set on the app. “You can only set three at a time, because we do not want to overwhelm [users] with a bunch of different things,” says Salvi. “I mean, I'm an overachiever. I probably would set every single goal and then fail at them.” And heaven knows we don’t need yet another way for busy, overwhelmed women to feel like they’re failing in a society with unsurmountable standards.

Forecasting the future

A woman walks up to the weight rack in 2024. She sees the usual suspects—bros pounding protein shakes and grunting through their bicep curls—but now she also sees a fair amount of women on the scene. They’ve got creatine supplements! Fitness trackers! Kettlebells! (And no, they aren’t pink.)

Granted, we still have a ways to go before women feel totally embraced by the biohacking space (we’d first have to close the centuries-long gender gap in science and medicine), but it’s clear that the arena is becoming way less of a boy’s club. “And the world is ready, my friend,” says Lyon. “The world is absolutely ready for this.”

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The movement emphasizes personalized experimentation, aiming to enhance quality of life and reduce susceptibility to disease—sometimes with an eye toward longevity.

According to the studies, how does intermittent fasting help?

It reduces the risk of lifestyle-related diseases, such as metabolic disorders.

Biohacking in its most common forms originated in Silicon Valley as a strategy for “upgrading” the body by influencing biological processes, largely without genetic modification.

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Content: Home » biohacking, reprogramming mind and body to live better

biohacking, reprogramming mind and body to live better

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It’s called “biohacking” and it comes from Silicon Valley. Listen: The long life diet: the longevity formula is calorie restriction …

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It’s called “biohacking” and comes from Silicon Valley.

A relatively new word that comes from the union of “biology” and “hacker” and indicates the attempt to positively influence the functioning of the organism, by hacking, ie trying to “force”, one’s genetic heritage. A strategy to live better and longer launched years ago by Californian top managers and which then spread throughout the world. How to upgrade the “operating system” of the human body? No manipulation, here we are talking about “reprogramming” and new lifestyles. “Our genetic heritage has enormous unexpressed potential that can be activated,” he explains Fabio Piccinidoctor and psychoanalyst, researcher of Food Sciences of theMarche Polytechnic University, author of the book “Biohacking Techniques: how to optimize metabolism to increase health and longevity”. “Biohacking aims to activate epigenetic modifications by awakening dormant genes to enhance the body’s resources.” While genetics studies the structure of DNA, epigenetics the way genes express themselves, i.e. how much they are turned on or off. “We’re talking about a set of strategies that aim to strengthen the body from a physical and mental point of view, first of all through nutrition, sleep quality, physical activity, cognitive stimulation”. One of the pillars of biohacking and the intermittent fasting, Piccini adds, which plans to concentrate the diet in a precise time span of the day (to be followed always under medical supervision). «But it is equally important to take care of sleep, we know very well that sleep debt accelerates aging and that 30-40 percent of people sleep too little. Just as it is essential to check thehydration. Physical training must also be intermittent, with recovery periods in place to allow the muscle layers to rebuild. And then, you have to keep learning something at any age, another pillar of biohacking: studying music or a new language, for example, to counteract cognitive degeneration”.

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THE QUALITY OF LIFE

Sandra Milo is one of the supporters of this well-being and longevity strategy. «I’m lucky, at 90 I’m in full health and I still have a great desire to enjoy life. I don’t know if it’s a matter of genetics, nor do I think there is a “magic formula” of longevity, but I have certainly always been careful to lead a healthy life. There is nothing more beautiful than reaching old age with a smile and in full autonomy », says the actress who baptized the first Biohacking Suite in Rome. “Our mission is not so much to lengthen life but to improve its quality by lowering the rate of morbidity,” explains Dr. Claudio Urbani, specialist in regenerative medicine, neuroscience and stress therapy, head of the longevity center Umb. «Biohacking aims to modify dormant functional responses from non-use, from muscular or cardiovascular function to flexibility. It is about regaining possession of the body and the mind-body axis, starting with stress management». Diagnosing your own state of “aging” involves a series of tests. «The measurement of oxidative stress which measures the quantity of free radicals and indicates any inflammatory states, plethysmography to evaluate the functionality of the microcirculation of the legs, impedancemetry to study body composition, fat and lean mass, nutritional status and hydration level. And only after the check is a tailor-made program created for each person. Among the suggested therapies, there is also that of the cold which stimulates the metabolism and reduces inflammation ».

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The goal is often to activate perceived “untapped” or “unexpressed” potential, leveraging epigenetic changes—changes in gene activity influenced by environment and behavior.

Core philosophies center on self-quantification, ongoing adjustment of routines, and an ethos of personal responsibility for health outcomes.

Rather than seeking shortcuts, practitioners—increasingly from diverse backgrounds—often use habit modifications, technology tracking, and diagnostic tests to guide their choices.

Title:

Content: Biohacking is a controversial practice, but Lepht Anonym accepts its risks. More than once he has ended up in the ER, leaving doctors perplexed by inserting chips and even boxes with connectors into his body.

Centuries ago, when a doctor wanted to try a new vaccine or a new drug that he had created … he tested it on himself. Many died while developing new medicines.

Some biohackers they see themselves as those pioneering doctors of the Middle Ages: they test on their own body biotechnologies that aspire to improve the human being, cure diseases, and evolve the human condition, to achieve the desired happiness. And some have also died trying.

The biohacking, also known by the name of DIY biology or DIYbio, has as purpose improve our human condition making nanotechnology, genetic engineering, and technological implants available to everyone. You have more information on this card:

From its origins, Humanity pursues immortality and eternal youth. Biohacking seeks to improve our human condition with cybernetic implants. We explain who biohackers are, and why chips are installed inside the body.

Biohackers implant chips, sensors, machines and other mechanisms with the aim of overcoming physical and intellectual limits.

There is an ethical branch o legal of biohacking that only experiments with implants that do not pose a health hazard, for example chips under the skin.

But another trend is committed to not setting limits, even at the cost of putting your health at risk. Its objective is to defeat all diseases, aging and even death, with the help of technology. Then we will stop being human to become transhumans.

A first step towards posthumanism, where Humanity could dispense with its own body and live eternally as data in a neurological network.

Tips and guide to buy a next-generation sports watch that fits your needs and helps you improve your sports goals.

Within these biohackers, grinders they are the most extreme version. It is the case of Lepht Anonym, a British biohacker that, as he tells us Business Insider, more than 50 chips, antennas and other devices have been implanted in the body.

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As only professionals can use anesthesia, all Lepht Anonym implants have been inserted into your body by volunteers, to live. Your goal is “improve our quality of life through technology“.

Lepth explains on his blog that inserts its own chips because “there is no other easy way to do it. I will not wait for someone with a research laboratory to endorse this search.“.

The first chip that this biohacker was implanted under the skin, it allowed pay in stores simply by touching the card reader.

It was also implanted some magnets under the fingers, which detected external sensors to feel the distance between hands and objects. This could help blind people to move without hitting obstacles.

Hackers and the computer world are increasingly present in television fictions. Surely at the moment we can think of a series that deals with these topics, but if you can only think of one or two, we have selected a few about hackers that we find interesting.

His latest experiment, last year, has been his most troublesome. A box several centimeters long, with antennas, USB storage and connectors, was inserted under the arm. All went well until he hit his arm in a taxi, and began to swell. He had to go to the emergency room:

There the doctors told me that I was fatal, that they did not understand why I had put a box in my arm“.

In the end, he gave up: “They kept insisting that I take it off. I let them do it because they discovered that a hole had opened in one corner of the device and a large amount of a viscous substance was coming out“.

After that incident, Lepht Anonym has not updated his blog again.

The biohacking it is a practice that is just beginning. But without a doubt, it will go further. There are already medical biohackers, and the goal is to incorporate this branch of technology into medicine.

Put it in the hands of experts, because people’s health is at stake.

The field has expanded to consider women’s physiological needs (such as fertility and hormonal cycles), and there is growing recognition that biohacking should favor flexibility and personalization over rigid regimens.

Popular nutritional biohacks include strict diets intended to lower inflammation, control blood sugar, or “optimize” the gut.

Typical examples include the ketogenic (high-fat, very low-carb) diet, gluten-free and dairy-free diets, and intermittent fasting (cycling between periods of eating and fasting).

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Content: I’m 58 but have a biological age of 21 – this is how I did it

After eight rounds of failed fertility treatments and a rheumatoid arthritis diagnosis, Leslie Kenny changed her lifestyle with the aim of reducing inflammation – the results, she says, were dramatic

Leslie Kenny was 39 and had endured eight rounds of failed fertility treatments, including IVF using a donor egg, when her doctor delivered even more bad news: the pain she’d been feeling in her wrists and fingers was rheumatoid arthritis (RA), and her blood tests showed signs of the disabling autoimmune condition lupus.

“The doctor prescribed me immunosuppressants and said, ‘You have five good years left’,” Kenny says. “I don’t know what that meant but I took it as ‘that’s all you’ve got’ – that this was the end. I was crushed.”

Lupus is an autoimmune condition in which the immune system attacks the body’s own tissues and causes inflammation that can cause permanent damage to the skin, joints, heart, lungs, kidneys and even the brain. There is no known cure, although it may relapse and remit. RA, another autoimmune condition, affects the joints leading to inflammation and thickening in the joints, which causes pain and reduced mobility. Again, there are treatments available, but it cannot be cured.

That bombshell diagnosis came in 2004. Today, Kenny is 58 and a slim, healthy woman with boundless energy. Her arthritis and lupus – a diagnosis she now questions – have gone into remission. But more than that, she appears to have beat the ageing process: recent blood tests show her biological age is just 21.

She took the “GlycanAge” blood test while attending a conference on longevity in the US. It is offered by a London-based bioinformatics company and measures levels of inflammation in your body. The results are based on determining the process of ageing as an accumulation of damage to your body over time by over-activation of the immune system, leading to inflammation of the tissues and cells. The result generates an estimated “biological age” depending on the average level of inflammation observed in the body at various points during a normal lifespan.

“Inflammation is the thing that I have been paying attention to for the last 19 years, so I suppose it’s not a surprise,” Kenny says.

Kenny is likely one of only a handful of people who could achieve such results. She is one of a breed of ‘biohacking’ devotees who swear by putting cutting-edge research into cell rejuvenation into practice in their own lives to keep their bodies and minds young, and to fight off the common causes of ageing, including inflammation, high blood sugar and cardiovascular degeneration.

The most well known of these biohackers is Bryan Johnson, the American multi-millionaire entrepreneur and venture capitalist. At 46, he spends $2m (£1.5m) a year on treatments and techniques – including restricting calories, taking large amounts of daily supplements, a strict sleep schedule that involves early nights and very early mornings, and blood transfusions – in an attempt to stop the ageing process.

He claims to have reversed his heart age by five years and has the lung capacity of an 18-year-old. Of his particular quest, Kenny reflects: “That very British saying ‘horses for courses’ comes to mind… but he is biohacking for immortality, whereas I prefer to think of myself as ‘bioharmonising’ for a healthy lifespan.”

Kenny is the co-founder of a not-for-profit group, the Oxford Longevity Project, whose aim is to get the latest groundbreaking ideas and research findings on anti-ageing and longevity to the widest possible audience – and she’s testing them out on her own body.

She set up the organisation with Oxford biologist Professor Denis Noble; Dr Paul Ch’en, a GP with a special interest in the ageing process; and academic and multiple marathon runner Sir Christopher Ball. Kenny brings lived experience as a patient who has seen her own health transformed by putting the latest academic findings into practice.

It was the shock of such a devastating diagnosis at such a young age that prompted Kenny to start doing her own research into autoimmune conditions and inflammation. It encouraged her to turn away from the pharmaceutical answers given by her doctors and find a new approach.

“I did try immunosuppressants and I really hated them. You had to jab yourself in the tummy. There are lots of bruises and it hurts. I just felt I shouldn’t be doing this,” she explains. “I have more of an Asian philosophical orientation, of the idea of bringing the body into balance rather than ‘let’s squash this symptom’. What I wanted to do was bring the body back into harmony.”

Back in 2004 the internet was still in its relative infancy, but patient groups had already started forming to share information on common health conditions. Kenny searched for anything she could find about the link between autoimmune disorders and inflammation in the body. She found there were common causes of inflammation including poor diet, lack of sleep, stress and undiagnosed allergies.

Kenny quit her job (she was, at the time, running a matchmaking agency) to reduce stress and improve sleep, and then overhauled her diet. Allergy testing found she was reacting to wheat and dairy, so she cut both out, and also reduced her sugar intake.

“At the time the idea that sugar was bad for you was kind of a new thing, but I removed sugar from my diet as much as I could and then took lots of foods that were anti-inflammatory,” she says. This involved a largely plant-based diet, also including oily fish such as salmon, lots of extra virgin olive oil and plant milks. She followed guidance from Dr Barry Sears, whose bestselling book The Zone Anti-Inflammatory Diet, had been recently released.

Then, after much discussion with autoimmune sufferers in the US, Kenny took a very radical – and expensive – step: online patient networks in the US were recommending intravenous immunoglobulin, a treatment that resets the immune system by replacing antibodies in your blood but was not recommended on the NHS. Kenny underwent two eight-hour blood transfusions at a hospital in Denver, Colorado in the United States, costing £24,000 and funded by health insurance provided by her then-husband’s employer. It is offered as a treatment for some conditions on the NHS, but not for lupus or RA.

Six months later her blood results had been reversed. The three readings her doctor was monitoring – C Reactive Protein, cytokines and TNFalpha, all of which measure inflammation and the function of the immune system – had reduced rapidly. Her doctor reported that her lupus appeared to be in full remission and she was free of disease and in control of her arthritis symptoms.

Kenny’s rapid success at improving her health kicked off a passion for self-management of illness and ageing that has defined her last two decades. “I really feel that patients need to have a chance of a fair fight,” she says, adding that not everyone can afford expensive blood infusions, but there are many things we can all do cheaply to improve our health.

Living in Oxford and surrounded by academics, Kenny began discussing her results with local friends and neighbours, including Lachlan MacKinnon, who was working on commercialising biotechnology for the Oxford Science Enterprise. He introduced her to Prof Katja Simon and Dr Ghada Alsaleh, who were both working at the Kennedy Institute for Rheumatology at Oxford University at the time, who had discovered something quite surprising – spermidine. “He [Lachlan] said, ‘It’s a terrible name, but it’s really interesting because it seems to be helping with the immune system’.”

In mice, spermidine – a polyamine found in high levels in plants such as mushrooms and fermented foods – was able to boost antibody levels in elderly subjects, keeping the immune system strong, and activate the process of autophagy: a natural cell rejuvenation process that usually happens during periods of fasting.

You may have heard the word recently due to Rishi Sunak’s commitment to a 48-hour fast every week. Consuming spermidine is believed to make the same cellular process happen, but without the inconvenience of starvation. Studies are ongoing but the first published papers also show the same effect in humans as mice.

Kenny has been taking a spermidine supplement ever since, and now promotes these findings alongside other new research through the Oxford Longevity Project.

Kenny also follows a ketogenic diet, very low in carbohydrate and higher in protein, which some academic research shows can help to preventing and treat diabetes, controlling blood sugar spikes and reducing inflammation.

Kenny’s daily routine also includes supplements of collagen, antioxidant-rich raw cacao, and glutathione, which helps repair tissues. She takes HRT to manage her body’s transition through the menopause and says the progesterone helps with restful sleep.

Two days a week she fasts for 16 hours, but she admits “I’m not slavish about it”. More important is the foods you do eat. “The Japanese drink and smoke like chimneys but they only lose four years of life to this, but in the UK we lose 10. It’s because they’re microdosing every day with green tea, they’re eating natto, which is full of spermidine; they’re eating fish full of Omega 3, and lots of fermented foods.”

Kenny walks her dog for at least 30 minutes a day and has an active life. She uses katsu bands, a product from Japan similar to a blood pressure cuff, which pulls the blood into one limb for 30 seconds then when it releases “the blood hits the pituitary gland and says ‘I’ve been lifting heavy weights’, and sends hormones to repair the body,” she explains.

She also uses an inversion chair – a small stool that makes doing a headstand easy for anyone, whatever their age – that trains the core and stimulates the vagus nerve, responsible for the regulation of organ functions such as digestion, heart rate and respiratory rate.

The efforts of figures like Kenny are being watched by experts. Vasa Curcin, professor of health informatics at King’s College London, says the “exciting work” going on among the global community of biohackers is “a huge opportunity to raise awareness and identify challenges for novel therapies and lifestyle tech interventions”.

But he adds: “We need to start considering pragmatic methods that would allow for these efforts to stop being just anecdotal evidence and start contributing to larger knowledge bases to support scientifically rigorous validation studies.”

So what is Kenny’s advice to the rest of us? “The most important thing is to get started and just do one thing. Whether that’s diet or putting a weight by the kettle and doing a bicep curl while you boil it. Just ask yourself to do it once a week, and the next week do it twice a week. Do it slowly and then it becomes a habit.”

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The “bulletproof” diet—a variation on ketogenic eating that favors high-quality fats, especially in the form of coffee blended with butter or oil—is also prominent.

Many biohackers additionally avoid processed foods and sugar, favoring anti-inflammatory foods like oily fish, olive oil, fermented products, and plant-based milk alternatives.

There is widespread interest in identifying food sensitivities through allergy testing.

Supplement use is common and can include collagen, glutathione, antioxidant-rich foods, and compounds like spermidine.

Physical activity-related biohacking covers regular, sometimes intense, physical exercise.

Practices include resistance training, high-intensity interval training (HIIT), and novel methods such as katsu bands (which restrict blood flow to enhance muscle adaptation) or inversion chairs for neurological stimulation.

A frequently cited intervention is cold exposure, including ice baths, which are claimed to reduce inflammation and stimulate metabolism.

Recovery is also a focal point, with adherents designing cycles of activity and rest to maximize muscle and nerve repair.

Supplementation is a central element, with many individuals taking a wide variety of vitamins, minerals, antioxidants, and compounds marketed for longevity, cognitive enhancement, or inflammation reduction.

Stacks (combinations) of supplements can include both common substances (vitamin D, omega-3s) and niche or experimental ones (such as spermidine, glutathione, or nootropics).

While some supplementation targets confirmed deficiencies or evidence-backed needs, the high intake of multiple and high-dose supplements can raise the risk of interactions, toxicity, or unknown health impacts.

Self-quantification and ongoing medical screening are fundamental to many biohackers, who regularly undergo blood testing to track markers of inflammation (such as CRP and cytokines), monitor hormone levels, or assess “biological age.”

The use of wearable devices (such as heart rate variability monitors or sleep trackers) is widespread for real-time metric tracking.

Specialized apps and wearables have emerged targeting female users, providing tailored data about hormonal cycles, fertility, and pregnancy.

Mental health and cognitive optimization are also common biohacking targets.

Practices include meditation, mindfulness, sleep tracking and improvement, and the use of “habit stacking” (building multiple health practices into daily routines).

Nootropics (substances marketed for cognitive enhancement) and, less commonly, prescription drugs like antidepressants are sometimes used, sometimes as part of self-experimentation for perceived increases in alertness, focus, or well-being.

There is a notable trend toward promoting balance and warning about mental health harms from obsessive optimization or the pursuit of perfection.

Some biohackers pursue more extreme interventions.

The “grinder” subculture experiments with technological implants or body modifications, such as chips, magnets, or sensors under the skin.

While some interventions (e.g., implantable payment chips) are relatively benign, others are unregulated and carry substantial medical risks including infections, device failure, or unintended health consequences.

Expert opinion stresses that technological body modification should proceed only under professional medical oversight.

In terms of scientific backing, a number of biohacking techniques overlap with evidence-based recommendations: regular physical activity, increased sleep quality, and anti-inflammatory dietary patterns (Mediterranean-style diets rich in fish and olive oil) are broadly supported in clinical research and associated with lower risk of chronic disease and improved longevity.

Practices like intermittent fasting have some clinical support for metabolic health and weight loss outcomes, though long-term studies, especially in those without metabolic disease, are limited.

According to the studies, how does intermittent fasting help?

It reduces the risk of lifestyle-related diseases, such as metabolic disorders.

Likewise, some specific supplements (e.g., vitamin D in cases of deficiency, omega-3 fatty acids for cardiovascular health) are supported by research.

Conversely, more extreme approaches—such as multiple restrictive diets simultaneously, very high supplement doses, use of experimental compounds, prolonged or extreme fasting, and unregulated device implantation—generally lack robust evidence from well-controlled, long-term human studies and may expose individuals to health risks.

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Personal experience
Anush Aleksanyan
“It ’ s funny when you can hire a top manager while in jail ”: Sergey Fage about prison,“ insights ” after it and biohacking
After a month in jail and seven months of house arrest on suspicion of drug smuggling, the entrepreneur learned to delegate, cope with stress and began to take fewer drugs.
He told the channel “Book Man ” about it.
About life under arrest
According to Fage, the “Russian prison ” was not what he imagined it:“ no one poked knives at anyone, everyone took care of each other ”, helped to get the necessary things, for example, coffee and cigarettes.
“I felt a community.
It was curious: people get into a difficult situation and behave more humanely than those who are at large, ” says the entrepreneur.
According to him, the pre-trial detention center is a rather comfortable place for those who in ordinary life are used to controlling everything and taking on many tasks.
There, the entrepreneur learned to delegate them to partners, and at that time he put on earplugs, a sleep mask and meditated - for 3-4 hours a day: "such is the inner zen in the middle of a hurricane."
In his spare time, Fage read books — Marshall McLuhan, Alexandre Dumas, Ernest Hemingway — and wrote letters to friends.
According to him, he accumulated 2 kg of printed letters for a month in jail.
He also engaged in fundraising - remotely attracted employees to their projects.
How he was released
According to Fage, he was released because the prosecutor did not have enough evidence of his guilt in drug smuggling.
This was also helped by “good lawyers ”, they managed to prove that the entrepreneur did not have“ malicious intent ”.
The main “Insights ”
Fage sees criminal prosecution as an experience “sent by life to learn something. ”
He says that if he were imprisoned for several years, he would continue to meditate, read books, and send people letters from prison.
While in prison, Fage also realized how much correctional facilities in Russia do not correspond to “notions of humanism ” and“ rational economic progress. ”
According to him, the problem is that people there do not have the opportunity to learn, although it would help them in the future to “generate less extreme ”.
About biohacking
Fage has been addicted to biohacking since 2014: in consultation with doctors, he takes supplements, antidepressants and other drugs to “become healthier and happier. ”
He described his experience here in detail.
Fage calls biohacking one of the elements of transhumanism, which helps to increase its effectiveness “here and now ”: to increase stress resistance, mood, to become more energetic.
The entrepreneur is sure that the extension of life is the main issue facing humanity today.
The idea of transhumanism is associated with one of the new projects of Fage: within two years, he plans to launch a medical service in the United States by subscription.
Exactly how it will work, he did not specify.
In an article on Medium, the entrepreneur criticizes modern medicine for being conservative.
For example, he said, the usual doctor would not recommend drugs that could benefit the patient - hormonal supplements or rapamycin, which is being studied as a potential "cure for old age."
Fage believes that this system needs to be changed.
At the same time, Fage himself, according to him, began to take less drugs after the story of the arrest.
About why it has become easier for people
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Most risks associated with biohacking arise from extreme, unsupervised, or poorly informed practices.

These include negative effects from high or prolonged use of certain supplements (potential toxicity or interactions), nutritional deficiencies from combined elimination diets, medical emergencies due to self-experimentation (especially with technology or potent drugs), and deterioration of mental health tied to perfectionism, social isolation, or stress.

What are the risks and dangers of diets?

Health authorities and medical experts note that while self-quantification and some “hacks” can increase awareness and motivation, biohacking should not replace medical care or established preventive health practices.

Interventions without robust evidence should be treated with skepticism and, if pursued, closely supervised by qualified professionals.

In summary, biohacking encompasses a spectrum from evidence-aligned health habits (such as improved diet and physical activity) to extreme or speculative self-experimentation.

While some methods are grounded in research, many lack sufficient evidence, and there are real physical and psychological risks associated with extreme, rigid, or unsupervised regimens.

What are the risks and dangers of combining the keto diet and intermittent fasting?

What are the risks and dangers of diets?

Open communication and involving healthcare professionals are recommended for those engaging in intensive biohacking practices.

The field’s emphasis on personalization and tracking can empower individuals, but moderation and critical evaluation of claims—to distinguish science from hype—are essential for safety and well-being.