Biohacking is an emerging field combining biology with self-experimentation to optimize health, well-being, and longevity.

It originated in Silicon Valley as "DIY biology," where individuals attempt to "hack" or enhance their genetic potential and bodily functions through lifestyle modifications, technological aids, and sometimes invasive procedures.

The core principle involves "reprogramming" one’s body and mind by activating latent biological capabilities, often through epigenetic mechanisms that influence gene expression without altering DNA sequences .

Common biohacking techniques among enthusiasts include various dietary strategies such as intermittent fasting, ketogenic diets, elimination diets (gluten-free, dairy-free), and the "Bulletproof diet," all aimed at reducing inflammation and optimizing gut health.

Supplement intake is prevalent, with users often consuming multiple supplements purported to support muscle growth, cognitive function, anti-aging, and anti-inflammatory effects.

For instance, creatine supplementation is increasingly recognized for its benefits across genders in improving muscle mass and cognitive performance .

Physical activity regimens often extend to extreme and hormetic stress-inducing practices like cold exposure (ice baths), heat therapy (saunas), and intensive exercise routines with planned recovery.

Gut optimization commonly involves probiotics, prebiotics, and diet adjustments to target inflammation .

Besides lifestyle interventions, biohackers employ advanced technological tools, including wearable medical-grade devices that track biomarkers such as heart rate variability, sleep quality, hormonal fluctuations, and physical performance metrics.

Some experiment with DIY blood testing and personalized biomarker tracking.

There is a segment known as "grinders" who push boundaries by implanting cybernetic devices beneath their skin to augment sensory input or facilitate payments, though these interventions carry notable health risks and are currently not medically endorsed .

Mental health and cognitive optimization also form part of biohacking, with practices including meditation, neurofeedback, nootropic supplementation, goal setting, and techniques such as neuroscience-based calisthenics aimed at enhancing neuroplasticity and achieving flow states .

Regarding scientific support, while many biohacking approaches align with established health principles — such as reducing inflammation via diet, exercise, improving sleep, and stress management — robust clinical research is limited for the full spectrum of practices, particularly more extreme or self-experimental methods.

Evidence supports intermittent fasting’s metabolic benefits and the role of anti-inflammatory diets; creatine is well-studied for muscle and brain health.

However, some practices, especially invasive biohacking or high-dose supplementation, lack long-term safety data.

The field currently relies heavily on anecdotal evidence and individual experimentation rather than large-scale randomized clinical trials.

Medical experts urge caution, endorsing validated interventions and supervised approaches to avoid potential harm [936c65fa-80e6-47ba-8442-e5e77a4826a5_411498914; 73dc4426-e3fb-40cb-8c2d-9236031101af; caa85e37-6f84-4cdd-91ed-88f88ac63b80].

Some individuals, like Leslie Kenny, have documented personal success with biohacking-inspired lifestyle changes focusing on inflammation reduction, dietary adjustment, intermittent fasting, supplementation, and physical activity, leading to improved biomarkers and quality of life.

However, such cases remain exceptional and personalized, underscoring the need for scientific validation and professional guidance.

Concerns also exist regarding obsessive or "hustle culture" tendencies among biohackers, which may introduce psychological stress or orthorexic behaviors

[936c65fa-80e6-47ba-8442-e5e77a4826a5_411498914; 0f2ceda1-1145-419b-adad-243aa48471c2_868441574].

In summary, biohacking encompasses a broad range of self-directed health optimization techniques including targeted nutrition, supplement regimens, physical and mental exercises, and emerging technologies for biomarker tracking or physical augmentation.

While some methods have growing empirical support and align with mainstream recommendations on diet, exercise, and sleep, many experimental or extreme biohacks lack definitive clinical evidence and carry potential risks.

Family members concerned about a relative’s intense biohacking lifestyle should approach the topic with informed compassion, encouraging balanced practices backed by medical advice, and watch for signs of harmful obsession or unverified interventions.

Professional guidance from qualified healthcare providers is strongly advised in navigating and supporting safe health optimization efforts.

Biohacking is an emerging field combining biology with self-experimentation to optimize health, well-being, and longevity.

Title:

Content: Biohacking is a controversial practice, but Lepht Anonym accepts its risks. More than once he has ended up in the ER, leaving doctors perplexed by inserting chips and even boxes with connectors into his body.

Centuries ago, when a doctor wanted to try a new vaccine or a new drug that he had created … he tested it on himself. Many died while developing new medicines.

Some biohackers they see themselves as those pioneering doctors of the Middle Ages: they test on their own body biotechnologies that aspire to improve the human being, cure diseases, and evolve the human condition, to achieve the desired happiness. And some have also died trying.

The biohacking, also known by the name of DIY biology or DIYbio, has as purpose improve our human condition making nanotechnology, genetic engineering, and technological implants available to everyone. You have more information on this card:

From its origins, Humanity pursues immortality and eternal youth. Biohacking seeks to improve our human condition with cybernetic implants. We explain who biohackers are, and why chips are installed inside the body.

Biohackers implant chips, sensors, machines and other mechanisms with the aim of overcoming physical and intellectual limits.

There is an ethical branch o legal of biohacking that only experiments with implants that do not pose a health hazard, for example chips under the skin.

But another trend is committed to not setting limits, even at the cost of putting your health at risk. Its objective is to defeat all diseases, aging and even death, with the help of technology. Then we will stop being human to become transhumans.

A first step towards posthumanism, where Humanity could dispense with its own body and live eternally as data in a neurological network.

Tips and guide to buy a next-generation sports watch that fits your needs and helps you improve your sports goals.

Within these biohackers, grinders they are the most extreme version. It is the case of Lepht Anonym, a British biohacker that, as he tells us Business Insider, more than 50 chips, antennas and other devices have been implanted in the body.

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As only professionals can use anesthesia, all Lepht Anonym implants have been inserted into your body by volunteers, to live. Your goal is “improve our quality of life through technology“.

Lepth explains on his blog that inserts its own chips because “there is no other easy way to do it. I will not wait for someone with a research laboratory to endorse this search.“.

The first chip that this biohacker was implanted under the skin, it allowed pay in stores simply by touching the card reader.

It was also implanted some magnets under the fingers, which detected external sensors to feel the distance between hands and objects. This could help blind people to move without hitting obstacles.

Hackers and the computer world are increasingly present in television fictions. Surely at the moment we can think of a series that deals with these topics, but if you can only think of one or two, we have selected a few about hackers that we find interesting.

His latest experiment, last year, has been his most troublesome. A box several centimeters long, with antennas, USB storage and connectors, was inserted under the arm. All went well until he hit his arm in a taxi, and began to swell. He had to go to the emergency room:

There the doctors told me that I was fatal, that they did not understand why I had put a box in my arm“.

In the end, he gave up: “They kept insisting that I take it off. I let them do it because they discovered that a hole had opened in one corner of the device and a large amount of a viscous substance was coming out“.

After that incident, Lepht Anonym has not updated his blog again.

The biohacking it is a practice that is just beginning. But without a doubt, it will go further. There are already medical biohackers, and the goal is to incorporate this branch of technology into medicine.

Put it in the hands of experts, because people’s health is at stake.

It originated in Silicon Valley as "DIY biology," where individuals attempt to "hack" or enhance their genetic potential and bodily functions through lifestyle modifications, technological aids, and sometimes invasive procedures.

Title:

Content: Home » biohacking, reprogramming mind and body to live better

biohacking, reprogramming mind and body to live better

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It’s called “biohacking” and it comes from Silicon Valley. Listen: The long life diet: the longevity formula is calorie restriction …

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It’s called “biohacking” and comes from Silicon Valley.

A relatively new word that comes from the union of “biology” and “hacker” and indicates the attempt to positively influence the functioning of the organism, by hacking, ie trying to “force”, one’s genetic heritage. A strategy to live better and longer launched years ago by Californian top managers and which then spread throughout the world. How to upgrade the “operating system” of the human body? No manipulation, here we are talking about “reprogramming” and new lifestyles. “Our genetic heritage has enormous unexpressed potential that can be activated,” he explains Fabio Piccinidoctor and psychoanalyst, researcher of Food Sciences of theMarche Polytechnic University, author of the book “Biohacking Techniques: how to optimize metabolism to increase health and longevity”. “Biohacking aims to activate epigenetic modifications by awakening dormant genes to enhance the body’s resources.” While genetics studies the structure of DNA, epigenetics the way genes express themselves, i.e. how much they are turned on or off. “We’re talking about a set of strategies that aim to strengthen the body from a physical and mental point of view, first of all through nutrition, sleep quality, physical activity, cognitive stimulation”. One of the pillars of biohacking and the intermittent fasting, Piccini adds, which plans to concentrate the diet in a precise time span of the day (to be followed always under medical supervision). «But it is equally important to take care of sleep, we know very well that sleep debt accelerates aging and that 30-40 percent of people sleep too little. Just as it is essential to check thehydration. Physical training must also be intermittent, with recovery periods in place to allow the muscle layers to rebuild. And then, you have to keep learning something at any age, another pillar of biohacking: studying music or a new language, for example, to counteract cognitive degeneration”.

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THE QUALITY OF LIFE

Sandra Milo is one of the supporters of this well-being and longevity strategy. «I’m lucky, at 90 I’m in full health and I still have a great desire to enjoy life. I don’t know if it’s a matter of genetics, nor do I think there is a “magic formula” of longevity, but I have certainly always been careful to lead a healthy life. There is nothing more beautiful than reaching old age with a smile and in full autonomy », says the actress who baptized the first Biohacking Suite in Rome. “Our mission is not so much to lengthen life but to improve its quality by lowering the rate of morbidity,” explains Dr. Claudio Urbani, specialist in regenerative medicine, neuroscience and stress therapy, head of the longevity center Umb. «Biohacking aims to modify dormant functional responses from non-use, from muscular or cardiovascular function to flexibility. It is about regaining possession of the body and the mind-body axis, starting with stress management». Diagnosing your own state of “aging” involves a series of tests. «The measurement of oxidative stress which measures the quantity of free radicals and indicates any inflammatory states, plethysmography to evaluate the functionality of the microcirculation of the legs, impedancemetry to study body composition, fat and lean mass, nutritional status and hydration level. And only after the check is a tailor-made program created for each person. Among the suggested therapies, there is also that of the cold which stimulates the metabolism and reduces inflammation ».

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The core principle involves "reprogramming" one’s body and mind by activating latent biological capabilities, often through epigenetic mechanisms that influence gene expression without altering DNA sequences .

Common biohacking techniques among enthusiasts include various dietary strategies such as intermittent fasting, ketogenic diets, elimination diets (gluten-free, dairy-free), and the "Bulletproof diet," all aimed at reducing inflammation and optimizing gut health.

Supplement intake is prevalent, with users often consuming multiple supplements purported to support muscle growth, cognitive function, anti-aging, and anti-inflammatory effects.

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Biohacking & Toxic Masculinity: How Women Dismantled The Boys Club

Author: Medical reviewer:
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By Jamie Schneider
Beauty & Health Editor
Jamie Schneider is the Beauty Editor at mindbodygreen. She has a B.A. in Organizational Studies and English from the University of Michigan, and her work has appeared in Coveteur, The Chill Times, and Wyld Skincare.
Medical review by
Bindiya Gandhi, M.D.
Physician
Dr. Bindiya Gandhi is an American Board Family Medicine–certified physician who completed her family medicine training at Georgia Regents University/Medical College of Georgia.
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Take a quick search for “biohacker” on TikTok (a tag with over 137 million views), and you’ll discover a slew of men discussing their muscle gains, testosterone levels, and cold plunge routines. You’ll see some women on the page, but the space is undoubtedly dominated by male energy. And think of the outspoken biohackers you may listen to on podcasts—chances are most of them are men, too.

This gendered approach to biohacking, while pervasive, is simply misguided. But now, women are asserting their authority in health optimization, and we expect their emphasis to soar in the year ahead.

Meet the experts

Molly Maloof. M.D.

Molly Maloof. M.D. provides health optimization and personalized medicine to high-achieving entrepreneurs, investors, and technology executives. Since 2012, she has worked as an advisor or consultant to more than 50 companies in the digital health, consumer health, and biotechnology industries. Her company, Adamo Bioscience, is working on sexual health optimization.

Gabrielle Lyon, D.O.

Gabrielle Lyon, D.O. is a board-certified family physician leading a disruption in modern medicine that focuses on the largest organ in the body: skeletal muscle. With a background that includes a combined research and clinical fellowship in geriatrics and nutritional sciences at Washington University and undergraduate training in nutritional sciences at the University of Illinois, she is a subject-matter expert on protein for health, performance, aging, and disease prevention.

Stacy Salvi

Stacy Salvi is the vice president of product and strategy at the medical device company Movano Health—the creator of the Evie Ring, the first medical-grade health wearable designed for women.

Mona Vand, PharmD

Mona Vand, PharmD studied pharmacy at Massachusetts College of Pharmacy and Health Sciences before developing her platform that shares holistic wellness advice.

Why biohacking isn’t just for “bros”

“Women are the original biohackers,” declares family physician, Molly Maloof, M.D. “Our hormones change throughout our lives, and this requires us to adapt accordingly.” Our biology means that women often need to constantly edit their health routines and experiment with lifestyle habits as time goes on. Isn’t that the very definition of biohacking?

Let's back up: Here at mindbodygreen, we think of “biohacking” as the practice of making lifestyle tweaks to optimize health and promote longevity. Not shortcuts—contrary to popular belief—but low-lift, everyday habits that complement and enhance an existing well-being routine. Think: optimizing your exercise regimen using tools and techniques (the “biohacks”) to enhance muscle growth. It’s essentially all about advancing health with “do it yourself” biology—a topic that can pique anyone’s interest, regardless of gender.

“[Women] have a most complex physiological lifecycle that requires us to track and manage fertility, pregnancy, breastfeeding, sexuality, perimenopause, and menopause. So we should be looking at biohacking as a path to even greater health and owning the opportunity to improve our lives,” says Maloof.

Yet many women feel intimidated to enter the biohacking scene as it exists today, turned off by the male-dominated energy in the room.

Women are the original biohackers

Molly Maloof, M.D

“Biohacking has always grabbed my attention, and I want to learn, but it sometimes makes me really stressed out, because I go into this state of perfectionism where I have to do all the things,” says doctor of pharmacy and wellness practitioner Mona Vand, PharmD. “The few biohackers that I followed were all males… it just doesn't really resonate with my energy.”

This male energy is not only frustrating but can potentially harm women’s health in the long run. After all, building muscle, prioritizing protein, and keeping an eye on various health metrics are crucial for longevity—in some cases, these proactive measures can save lives. When women don’t get involved, it can totally impact their well-being.

“Physical strength is nonnegotiable,” says functional medicine doctor Gabrielle Lyon, D.O. “I've been a physician since 2006, and I've never heard someone say, ‘I regret being physically strong.’” And the muscle-building space impacts more than just physiological changes, she says. “You optimize fertility, you make healthier babies, you help the epigenetics of your child,” Lyon adds. “You age better, your skin is better, you're less likely to fall and break a hip… There's nothing that doesn't get better the stronger you are.”

So let’s be clear: Dismantling the biohacking boy’s club is not just about helping women feel included; there are real health implications at stake here.

Why the biohacker space actually really needs a dose of feminine energy

I’d be remiss not to mention how biohacking culture can easily become synonymous with hustle culture (some experts don’t even like to use the term, as it implies you can achieve optimal health with quick fixes). But as more women enter the biohacking space, we expect it to become more intuitive and less about hitting every single benchmark. From there, we predict women will focus more on sustainable changes long-term instead of a gazillion quick hacks.

“I used to think it was a flex to do a million things at the same time and habit stack,” Vand recounts. “I now carve out time for doing things that have no efficiency to them, that are strictly for joy or rest and relaxation, versus benefiting my longevity or health. It can be a little bit obsessive when you get into this thought pattern, and I just don't resonate with it.”

This doesn’t mean biohacking will become “softer” as it embraces feminine energy. But there’s an opportunity here for women to introduce some much-needed flexibility into a space that has long felt needlessly rigid.

How the biohacker game is changing — and where it’s headed next

Thanks to a growing awareness that healthcare protocols should not be gendered, more women are now starting to pay attention to markers of performance like lean muscle, hormetic stressors, VO2 max, HRV, zone 2 training, etc. “Cold plunging, saunas, and harder, more physical activities are not just for the boys anymore,” adds Lyon—and we expect an even bigger shift to come in 2024.

“I think it’s super exciting to see biohacking become more mainstream and more women joining the conversation,” adds Maloof. She praises apps like Wild.AI, for women who aim to make lifestyle adjustments based on their menstrual cycle, and Zero, for women who want to dabble in time-restricted eating, both of which have helped to herald the shift.

Other existing health optimization companies are now inviting women into the conversation by introducing specific features informed by their unique physiology. WHOOP, for example, is currently working on upgrades to their popular health-tracking band: “We did a study recently where we learned a lot about how a woman's body changes during pregnancy and how her heart rate variability (HRV) will evolve. It'll decrease, and then about seven weeks before she gives birth, it will increase sharply,” explains Will Ahmed, WHOOP founder and CEO, on the mindbodygreen podcast

If a woman didn’t know that this was supposed to happen, she might look at this stark increase with a critical (or anxious) eye. “We've been able to take population-level data on pregnant women and now have a feature in the app, where a woman can see how her body is evolving alongside what other pregnant women are experiencing,” he adds.

Similarly, creatine supplements—from the ingredients to the packaging—are no longer marketed toward dudes looking to bulk up, and we are certainly here for it. After all, muscle mass is a predictor of longevity and healthspan, so supplements that promote it can help all of us “hack” our health in a big way.

And as Lyon notes, women have lower endogenous creatine stores compared to men (meaning, they have less available). And the amino acid has been associated with significantly increased muscle mass1 in both men and women, without increasing the risk of adverse outcomes2, like weight gain. “Most of the women in my practice will go on creatine, and they find anecdotally that it really improves both anaerobic and aerobic exercise performance,” Lyon shares.

Not to mention the supplement’s brain health perks: Taking creatine has been shown to benefit both working memory and processing speed3 as well as cognitive longevity4. “It is above and beyond simply sport performance,” adds Lyon, who has certainly seen an uptick in women curious about creatine.

As women feel intimidated (or even restricted) by biohacking spaces, some experts have taken it upon themselves to create new ones that center the feminine. For example, neuropsychophysiologist Kayla Osterhoff, MPH, offers a Women's Biohacking Mini Course, consisting of lifestyle routines and tips aligned with female physiology.

Osterhoff also recently presented at the 2023 Dragonfly Live Conference—among other female biohackers—to discuss the latest advancements in women's well-being and the “health revolution” that’s sweeping the mainstream. This conference aims to gather the “who's-who” in the health space to discuss cutting-edge strategies and innovations that optimize well-being—by having women biohackers at the forefront of the conversation, we can expect them to hit the main stage in a broader sense.

Or take the brand new Evie Ring, the first medical-grade health wearable designed for women, created by medical device company Movano Health. The technology ties hormonal information to a woman’s sleep, activity, and heart health data (among other metrics).

For instance, “If we notice a more restless night of sleep in the luteal phase, we'll point it out and also give some strategies for how somebody may attack their day, despite having not gotten as good of a night of sleep,” says Stacy Salvi, vice president of product and strategy at Movano Health. Similarly, “We know that there are cardiovascular implications when your estrogen drops, so they would want to keep a better look on the function of their heart,” she adds. “This would be something that they would be able to do from our app.”

Even the design itself was made with women in mind: The ring features an open band meant to accommodate how women’s fingers change in size throughout the day, so it can stay comfortable.

To avoid needless stress, Evie also limits the amount of goals you can set on the app. “You can only set three at a time, because we do not want to overwhelm [users] with a bunch of different things,” says Salvi. “I mean, I'm an overachiever. I probably would set every single goal and then fail at them.” And heaven knows we don’t need yet another way for busy, overwhelmed women to feel like they’re failing in a society with unsurmountable standards.

Forecasting the future

A woman walks up to the weight rack in 2024. She sees the usual suspects—bros pounding protein shakes and grunting through their bicep curls—but now she also sees a fair amount of women on the scene. They’ve got creatine supplements! Fitness trackers! Kettlebells! (And no, they aren’t pink.)

Granted, we still have a ways to go before women feel totally embraced by the biohacking space (we’d first have to close the centuries-long gender gap in science and medicine), but it’s clear that the arena is becoming way less of a boy’s club. “And the world is ready, my friend,” says Lyon. “The world is absolutely ready for this.”

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For instance, creatine supplementation is increasingly recognized for its benefits across genders in improving muscle mass and cognitive performance .

Physical activity regimens often extend to extreme and hormetic stress-inducing practices like cold exposure (ice baths), heat therapy (saunas), and intensive exercise routines with planned recovery.

Gut optimization commonly involves probiotics, prebiotics, and diet adjustments to target inflammation .

Besides lifestyle interventions, biohackers employ advanced technological tools, including wearable medical-grade devices that track biomarkers such as heart rate variability, sleep quality, hormonal fluctuations, and physical performance metrics.

Some experiment with DIY blood testing and personalized biomarker tracking.

There is a segment known as "grinders" who push boundaries by implanting cybernetic devices beneath their skin to augment sensory input or facilitate payments, though these interventions carry notable health risks and are currently not medically endorsed .

Mental health and cognitive optimization also form part of biohacking, with practices including meditation, neurofeedback, nootropic supplementation, goal setting, and techniques such as neuroscience-based calisthenics aimed at enhancing neuroplasticity and achieving flow states .

Regarding scientific support, while many biohacking approaches align with established health principles — such as reducing inflammation via diet, exercise, improving sleep, and stress management — robust clinical research is limited for the full spectrum of practices, particularly more extreme or self-experimental methods.

Title:

Content: I’m 58 but have a biological age of 21 – this is how I did it

After eight rounds of failed fertility treatments and a rheumatoid arthritis diagnosis, Leslie Kenny changed her lifestyle with the aim of reducing inflammation – the results, she says, were dramatic

Leslie Kenny was 39 and had endured eight rounds of failed fertility treatments, including IVF using a donor egg, when her doctor delivered even more bad news: the pain she’d been feeling in her wrists and fingers was rheumatoid arthritis (RA), and her blood tests showed signs of the disabling autoimmune condition lupus.

“The doctor prescribed me immunosuppressants and said, ‘You have five good years left’,” Kenny says. “I don’t know what that meant but I took it as ‘that’s all you’ve got’ – that this was the end. I was crushed.”

Lupus is an autoimmune condition in which the immune system attacks the body’s own tissues and causes inflammation that can cause permanent damage to the skin, joints, heart, lungs, kidneys and even the brain. There is no known cure, although it may relapse and remit. RA, another autoimmune condition, affects the joints leading to inflammation and thickening in the joints, which causes pain and reduced mobility. Again, there are treatments available, but it cannot be cured.

That bombshell diagnosis came in 2004. Today, Kenny is 58 and a slim, healthy woman with boundless energy. Her arthritis and lupus – a diagnosis she now questions – have gone into remission. But more than that, she appears to have beat the ageing process: recent blood tests show her biological age is just 21.

She took the “GlycanAge” blood test while attending a conference on longevity in the US. It is offered by a London-based bioinformatics company and measures levels of inflammation in your body. The results are based on determining the process of ageing as an accumulation of damage to your body over time by over-activation of the immune system, leading to inflammation of the tissues and cells. The result generates an estimated “biological age” depending on the average level of inflammation observed in the body at various points during a normal lifespan.

“Inflammation is the thing that I have been paying attention to for the last 19 years, so I suppose it’s not a surprise,” Kenny says.

Kenny is likely one of only a handful of people who could achieve such results. She is one of a breed of ‘biohacking’ devotees who swear by putting cutting-edge research into cell rejuvenation into practice in their own lives to keep their bodies and minds young, and to fight off the common causes of ageing, including inflammation, high blood sugar and cardiovascular degeneration.

The most well known of these biohackers is Bryan Johnson, the American multi-millionaire entrepreneur and venture capitalist. At 46, he spends $2m (£1.5m) a year on treatments and techniques – including restricting calories, taking large amounts of daily supplements, a strict sleep schedule that involves early nights and very early mornings, and blood transfusions – in an attempt to stop the ageing process.

He claims to have reversed his heart age by five years and has the lung capacity of an 18-year-old. Of his particular quest, Kenny reflects: “That very British saying ‘horses for courses’ comes to mind… but he is biohacking for immortality, whereas I prefer to think of myself as ‘bioharmonising’ for a healthy lifespan.”

Kenny is the co-founder of a not-for-profit group, the Oxford Longevity Project, whose aim is to get the latest groundbreaking ideas and research findings on anti-ageing and longevity to the widest possible audience – and she’s testing them out on her own body.

She set up the organisation with Oxford biologist Professor Denis Noble; Dr Paul Ch’en, a GP with a special interest in the ageing process; and academic and multiple marathon runner Sir Christopher Ball. Kenny brings lived experience as a patient who has seen her own health transformed by putting the latest academic findings into practice.

It was the shock of such a devastating diagnosis at such a young age that prompted Kenny to start doing her own research into autoimmune conditions and inflammation. It encouraged her to turn away from the pharmaceutical answers given by her doctors and find a new approach.

“I did try immunosuppressants and I really hated them. You had to jab yourself in the tummy. There are lots of bruises and it hurts. I just felt I shouldn’t be doing this,” she explains. “I have more of an Asian philosophical orientation, of the idea of bringing the body into balance rather than ‘let’s squash this symptom’. What I wanted to do was bring the body back into harmony.”

Back in 2004 the internet was still in its relative infancy, but patient groups had already started forming to share information on common health conditions. Kenny searched for anything she could find about the link between autoimmune disorders and inflammation in the body. She found there were common causes of inflammation including poor diet, lack of sleep, stress and undiagnosed allergies.

Kenny quit her job (she was, at the time, running a matchmaking agency) to reduce stress and improve sleep, and then overhauled her diet. Allergy testing found she was reacting to wheat and dairy, so she cut both out, and also reduced her sugar intake.

“At the time the idea that sugar was bad for you was kind of a new thing, but I removed sugar from my diet as much as I could and then took lots of foods that were anti-inflammatory,” she says. This involved a largely plant-based diet, also including oily fish such as salmon, lots of extra virgin olive oil and plant milks. She followed guidance from Dr Barry Sears, whose bestselling book The Zone Anti-Inflammatory Diet, had been recently released.

Then, after much discussion with autoimmune sufferers in the US, Kenny took a very radical – and expensive – step: online patient networks in the US were recommending intravenous immunoglobulin, a treatment that resets the immune system by replacing antibodies in your blood but was not recommended on the NHS. Kenny underwent two eight-hour blood transfusions at a hospital in Denver, Colorado in the United States, costing £24,000 and funded by health insurance provided by her then-husband’s employer. It is offered as a treatment for some conditions on the NHS, but not for lupus or RA.

Six months later her blood results had been reversed. The three readings her doctor was monitoring – C Reactive Protein, cytokines and TNFalpha, all of which measure inflammation and the function of the immune system – had reduced rapidly. Her doctor reported that her lupus appeared to be in full remission and she was free of disease and in control of her arthritis symptoms.

Kenny’s rapid success at improving her health kicked off a passion for self-management of illness and ageing that has defined her last two decades. “I really feel that patients need to have a chance of a fair fight,” she says, adding that not everyone can afford expensive blood infusions, but there are many things we can all do cheaply to improve our health.

Living in Oxford and surrounded by academics, Kenny began discussing her results with local friends and neighbours, including Lachlan MacKinnon, who was working on commercialising biotechnology for the Oxford Science Enterprise. He introduced her to Prof Katja Simon and Dr Ghada Alsaleh, who were both working at the Kennedy Institute for Rheumatology at Oxford University at the time, who had discovered something quite surprising – spermidine. “He [Lachlan] said, ‘It’s a terrible name, but it’s really interesting because it seems to be helping with the immune system’.”

In mice, spermidine – a polyamine found in high levels in plants such as mushrooms and fermented foods – was able to boost antibody levels in elderly subjects, keeping the immune system strong, and activate the process of autophagy: a natural cell rejuvenation process that usually happens during periods of fasting.

You may have heard the word recently due to Rishi Sunak’s commitment to a 48-hour fast every week. Consuming spermidine is believed to make the same cellular process happen, but without the inconvenience of starvation. Studies are ongoing but the first published papers also show the same effect in humans as mice.

Kenny has been taking a spermidine supplement ever since, and now promotes these findings alongside other new research through the Oxford Longevity Project.

Kenny also follows a ketogenic diet, very low in carbohydrate and higher in protein, which some academic research shows can help to preventing and treat diabetes, controlling blood sugar spikes and reducing inflammation.

Kenny’s daily routine also includes supplements of collagen, antioxidant-rich raw cacao, and glutathione, which helps repair tissues. She takes HRT to manage her body’s transition through the menopause and says the progesterone helps with restful sleep.

Two days a week she fasts for 16 hours, but she admits “I’m not slavish about it”. More important is the foods you do eat. “The Japanese drink and smoke like chimneys but they only lose four years of life to this, but in the UK we lose 10. It’s because they’re microdosing every day with green tea, they’re eating natto, which is full of spermidine; they’re eating fish full of Omega 3, and lots of fermented foods.”

Kenny walks her dog for at least 30 minutes a day and has an active life. She uses katsu bands, a product from Japan similar to a blood pressure cuff, which pulls the blood into one limb for 30 seconds then when it releases “the blood hits the pituitary gland and says ‘I’ve been lifting heavy weights’, and sends hormones to repair the body,” she explains.

She also uses an inversion chair – a small stool that makes doing a headstand easy for anyone, whatever their age – that trains the core and stimulates the vagus nerve, responsible for the regulation of organ functions such as digestion, heart rate and respiratory rate.

The efforts of figures like Kenny are being watched by experts. Vasa Curcin, professor of health informatics at King’s College London, says the “exciting work” going on among the global community of biohackers is “a huge opportunity to raise awareness and identify challenges for novel therapies and lifestyle tech interventions”.

But he adds: “We need to start considering pragmatic methods that would allow for these efforts to stop being just anecdotal evidence and start contributing to larger knowledge bases to support scientifically rigorous validation studies.”

So what is Kenny’s advice to the rest of us? “The most important thing is to get started and just do one thing. Whether that’s diet or putting a weight by the kettle and doing a bicep curl while you boil it. Just ask yourself to do it once a week, and the next week do it twice a week. Do it slowly and then it becomes a habit.”

Most Read By Subscribers

Evidence supports intermittent fasting’s metabolic benefits and the role of anti-inflammatory diets; creatine is well-studied for muscle and brain health.

According to the studies, how does intermittent fasting help?

It reduces the risk of lifestyle-related diseases, such as metabolic disorders.

However, some practices, especially invasive biohacking or high-dose supplementation, lack long-term safety data.

The field currently relies heavily on anecdotal evidence and individual experimentation rather than large-scale randomized clinical trials.

Is there clinical evidence for benefits of short intermittent fasting methods?

Clinical evidence for fasting as long as seven days is not yet available.

Medical experts urge caution, endorsing validated interventions and supervised approaches to avoid potential harm [936c65fa-80e6-47ba-8442-e5e77a4826a5_411498914; 73dc4426-e3fb-40cb-8c2d-9236031101af; caa85e37-6f84-4cdd-91ed-88f88ac63b80].

Some individuals, like Leslie Kenny, have documented personal success with biohacking-inspired lifestyle changes focusing on inflammation reduction, dietary adjustment, intermittent fasting, supplementation, and physical activity, leading to improved biomarkers and quality of life.

According to the studies, how does intermittent fasting help?

It reduces the risk of lifestyle-related diseases, such as metabolic disorders.

However, such cases remain exceptional and personalized, underscoring the need for scientific validation and professional guidance.

Concerns also exist regarding obsessive or "hustle culture" tendencies among biohackers, which may introduce psychological stress or orthorexic behaviors

[936c65fa-80e6-47ba-8442-e5e77a4826a5_411498914; 0f2ceda1-1145-419b-adad-243aa48471c2_868441574].

In summary, biohacking encompasses a broad range of self-directed health optimization techniques including targeted nutrition, supplement regimens, physical and mental exercises, and emerging technologies for biomarker tracking or physical augmentation.

While some methods have growing empirical support and align with mainstream recommendations on diet, exercise, and sleep, many experimental or extreme biohacks lack definitive clinical evidence and carry potential risks.

Family members concerned about a relative’s intense biohacking lifestyle should approach the topic with informed compassion, encouraging balanced practices backed by medical advice, and watch for signs of harmful obsession or unverified interventions.

Professional guidance from qualified healthcare providers is strongly advised in navigating and supporting safe health optimization efforts.


The reconversion of Hagia Sophia from a museum into a mosque by Turkish President Recep Tayyip Erdogan in 2020 has generated significant controversy both domestically and internationally.

Historically, Hagia Sophia, originally built as a Byzantine cathedral in the 4th century, became an Ottoman mosque after the conquest of Constantinople in 1453, then a museum in 1934.

Erdogan’s decision reversed the 1934 directive, reinstating Hagia Sophia’s mosque status after 86 years of being a museum and igniting criticism on multiple fronts.

Critics, including UNESCO and the Greek government, argue that this move undermines the site’s character as a world heritage landmark emblematic of multi-faith coexistence and secularism in modern Turkey.

Greek Orthodox authorities and the U.S. State Department condemned the conversion as a disregard for Hagia Sophia’s Byzantine Christian heritage and a threat to religious pluralism.

Critics highlight concerns that the reconversion privileges the Islamic past of the building over its Christian art and history, especially as many Byzantine mosaics depicting Christian figures have been covered, restricting their visibility for worshippers and visitors alike .

Many observe that the reconversion serves as a political tool by Erdogan to mobilize his conservative and religious voter base amidst domestic challenges such as electoral setbacks and economic difficulties, including the aftermath of a severe 2023 earthquake and high inflation.

Analysts suggest Erdogan’s action is part of a broader Islamo-nationalist agenda, aiming to reinforce Turkish sovereignty and identity while signaling defiance against international criticism, which the Turkish government has labeled as politically motivated and biased [36db8615-aa07-4391-a3f5-098dba27f295_1069312408; 76e3d61c-e991-43a2-8ebe-637114089506_291378229].

Domestically, Turkish supporters regard the reconversion as a restoration of national pride and historical legacy.

The reconversion of Hagia Sophia from a museum into a mosque by Turkish President Recep Tayyip Erdogan in 2020 has generated significant controversy both domestically and internationally.

Title:

Content: She returned Hagia Sophia to a mosque.
Turkey has challenged global trusteeship
Daily Morning
Istanbul, Turkey
Posted at 29.10.2022 10: 23
Hagia Sophia Mosque (Getty Images)
President Recep Tayyip Erdogan said Friday that the fact that Turkey has returned the Hagia Sophia museum from a museum to a mosque represents a major challenge to the global trusteeship.
Speaking at a ceremony announcing the vision of the ruling Justice and Development Party (AKP) “Turkey ’ s Century ” in Ankara, Erdogan said his country was challenging global tutelage and thanked citizens for their support for the decision to return Hagia Sophia.
He noted that his party has always sought to eliminate any vestiges of guardianship and promote democracy in the country over the past 20 years.
Turkey has lived through a remarkable period in its history in general and the history of Istanbul, especially when Hagia Sophia was transformed from its status as a museum and restored to its former glory as the Grand Mosque of Hagia Sophia on July 24, 2020.
The historic building remained a church for 916 years until the conquest of Istanbul.
It was then used as a mosque between 1453 and 1934, nearly 500 years before becoming a museum for 86 years.
It is one of the most visited historical buildings in Turkey by domestic and international tourists, and Hagia Sophia was added to the UNESCO World Heritage List in 1985.
On July 10, 2020, a Turkish court overturned a 1934 ministerial decision that turned Hagia Sophia into a museum, paving the way for it to be used again as a mosque after an 86-year hiatus.

Who was angered by the reconversion of Hagia Sophia in July 2020?

Historically, Hagia Sophia, originally built as a Byzantine cathedral in the 4th century, became an Ottoman mosque after the conquest of Constantinople in 1453, then a museum in 1934.

Title:

Content: The first Friday prayer in the old church of Istanbul that has been converted into a mosque - Sunrise Gate
Friday 10 May 2024 9: 23 PM Cairo Cairo 24 °
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First Friday prayers held in the old Istanbul church that has been converted into a mosque
Istanbul - (DPA)
Published on: Friday 10 May 2024 - 7: 21 PM | Last updated on Friday 10 May 2024 - 7: 21 PM
Muslims held Friday prayers at the historic ancient church of Chora, one of Istanbul ’ s most famous Byzantine era monuments, for the first time since it was converted into a mosque, state broadcaster TRT reported.
The Chora Church, formerly a museum, was officially converted into a mosque in 2020.
After lengthy restoration work, President Recep Tayyip Erdogan inaugurated the UNESCO World Heritage Site as a mosque on Monday.
It is noteworthy that in 2020, the famous Hagia Sophia church in Istanbul was converted into a mosque after a decree issued by Erdogan.
The two churches were converted into mosques after the Ottoman conquest of Istanbul in 1435.
The Hagia Sophia became a museum in 1935 and Chora in 1945, and the conversion of the two churches was met with international criticism.
Greek Prime Minister Kyriakos Mitsotakis criticized the transformation of Chora as "an act that offends Istanbul's rich history" ahead of his planned meeting with Erdogan on May 13 in Turkey.
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How did the role of Hagia Sophia change following the Ottoman conquest?

Sultan Mehmed II converted Hagia Sophia into a mosque,

Hagia Sophia became a central Islamic religious site for centuries

What was the original historical and cultural significance of Hagia Sophia in the Byzantine Empire?

Served as the central church of Byzantine Christianity,

Erdogan’s decision reversed the 1934 directive, reinstating Hagia Sophia’s mosque status after 86 years of being a museum and igniting criticism on multiple fronts.

How did Muslims and Orthodox Christians react to the reconversion?

What legal action enabled the 2020 reconversion of Hagia Sophia into a mosque?

1934 cabinet decree annulled by President Erdogan

Who was angered by the reconversion of Hagia Sophia in July 2020?

Critics, including UNESCO and the Greek government, argue that this move undermines the site’s character as a world heritage landmark emblematic of multi-faith coexistence and secularism in modern Turkey.

Title:

Content: After Hagia Sophia, Turkey converts a second ancient Byzantine church into a mosque

Hundreds of worshippers filled the narrow streets of Istanbul's Fatih district on Friday to hear the sounds of Friday prayers ringing out from the newly inaugurated Kariye Mosque.

Once known as the Chora Church, the site spent the last 79 years as a museum. But it is now the latest structure to be converted back into a mosque by the government of Recep Tayyip Erdoğan, following the conversion of Hagia Sophia in 2020. While viewed as a triumph by many Turkish Muslims, the Greek Orthodox Church has decried it as an "ill-advised decision" that "makes a mockery of the Turkish government's commitment to religious tolerance and religious freedom."

Chora's conversion was announced shortly after Hagia Sophia's, but its opening for prayer was delayed by years of restoration work.

The showing for the first Friday prayers at Kariye was relatively quiet compared to Hagia Sophia, which drew hundreds of thousands who filled the streets with prayer rugs for blocks and blocks away from the building. By contrast, the crowd on Friday was relatively average for a mosque in one of Istanbul's more religiously conservative neighborhoods, where Friday worshippers frequently spill out onto the streets.

Both the Chora Church and Hagia Sophia are 4th-century Byzantine constructions. They spent nearly a millennium as Christian holy sites before being converted to mosques by the Ottomans after their conquest of Constantinople in the 15th century. Despite their conversions, they remained revered by Orthodox Christians. After the founding of a secular Turkish Republic in the early 20th century, the decision was made for both to be neither mosque nor church but simply museums.

"Both Hagia Sophia and Chora embodied Byzantine and Ottoman pasts, and they became symbols of co-existence and multi-faith living practices. Their conversion fundamentally implies a hierarchy, prioritizing the Islamic past over all other layers, Greek Orthodox, Armenian, Jewish, Syriac, et al," Dr. Özgür Kaymak, a lecturer and researcher on minority rights at Istanbul's MEF University, told Religion News Service in an email.

Rededicating the sites as mosques is more than just a status change. According to Islamic tradition, artwork of human figures are forbidden in places of prayer, while in Orthodox Churches, icons of Christ, saints and other biblical figures are a defining feature.

In Hagia Sophia, the mosaics of Jesus and Mary have been covered with curtains since the conversion. While Erdoğan promised Hagia Sophia would remain fully accessible and free to all visitors, Turkey reneged on that earlier this year, reimposing an entrance fee on tourists and relegating them to the upper level, while the main floor is exclusive to Muslim worshippers.

Observers have also criticized the Turkish Directorate of Religion's caretaking of the site, noting damage that did not exist when it was under the purview of the Ministry of Culture and Tourism.

Though Chora is significantly smaller than Hagia Sophia, it is home to some of the best-preserved examples of late-Byzantine art, including mosaics, icons and frescoes, and is considered a UNESCO World Heritage site.

"For us it's a very important place because it remembers our culture and our traditions here," Father Evangelos Markantonis, an Orthodox priest who was leading a group of theology students to Chora on Friday, told Religion News Service.

"Though we cannot venerate as Orthodox Christians, we have to try to find things we can be united on. Only with dialogue and good deeds can we continue our lives," Markantonis, who is also a professor at the University of Athens, said when asked about the controversy.

Erdoğan had long refused calls from his right to convert churches like Hagia Sophia and Chora, telling supporters in 2018 to fill the nearby Sultan Ahmet Mosque (also known in English as the Blue Mosque) before they talked about needing to pray in Hagia Sophia.

Nonetheless, he made an about-turn in 2020.

"My dear nation, the conquest of Istanbul and the conversion of the Hagia Sophia into a Mosque are among the most glorious chapters in Turkish history," Erdoğan said at the time in a speech inaugurating the Hagia Sophia as a mosque.

"This is the most honorable day that Islam has been looking forward to, Greek Constantinople has become Turkish Istanbul," he added, quoting the Turkish poet Nazim Hikmet.

"The resurrection of Hagia Sophia heralds the liberation of the al-Aqsa Mosque. The resurrection of Hagia Sophia is the footsteps of the will of Muslims across the world to come out of the interregnum," Erdoğan said in his concluding remarks.

Chora's opening as the Kariye Mosque comes just weeks after Erdoğan's Justice and Development Party (AKP) suffered its largest electoral defeat in two decades during Turkey's nationwide municipal elections.

"The recent conversion of Chora into a mosque may be due to Erdoğan's many problems, including his geopolitical power politics, his appeal to religio-nationalism to revive his electoral popularity after the March elections or his tactic to divert attention from Turkey's economic downturn," Kaymak said.

Many analysts have attributed the loss to AKP bleeding votes to the more Islamist-leaning New Welfare Party, which has pressured Erdogan over his response to the Israel-Hamas war and humanitarian situation in the Gaza Strip.

Muslim worshippers at the mosque on Friday said they viewed its rededication as an Islamic site to be a national win for Turkey.

"This mosque is one of the symbols of the Conquest. We are proud and happy. There are very beautiful frescoes inside. They were also nicely renovated before they were closed. May it be good for our country and our nation," a bystander, Ahmet Öteyüzoğlu, told Turkish media.

"Thank God for these days. Not everyone has the opportunity in their lifetime," another bystander named Mehmet Çelik told the Turkish news service Anadolu Agency, in reference to having been able to pray at both the rededicated Hagia Sophia and Kariye Mosques.

However, Greece, the U.S. State Department and Orthodox Christian institutions worldwide have all criticized the decision to revert the structure into a mosque.

"I want to publicly express my intense dissatisfaction, interpreting the feelings of all Greek women and men, for the completely unnecessary conversion of a historic Byzantine temple, the Monastery of Chora, into a mosque. It is, I believe, an action that offends the rich history of Istanbul itself as a crossroads of cultures," Greek Prime Minister Kyriakos Mitsotakis said shortly before leaving for Turkey for a planned meeting with Erdogan.

"We encourage the Turkish government to preserve and ensure access to sites and buildings that have hosted different religious communities in a way that respects their diverse histories," a State Department spokesperson said in response to questions from Greek media.

"The Turkish government's appropriation of both as the property of one faith group not only constitutes yet another sign of that government's contempt for Turkey's rich Orthodox Christian heritage but further imperils the religious freedom of the Ecumenical Patriarchate and the remaining Christians of that land," the Archons of the Ecumenical Patriarchate said in a statement.

© Religion News Service

Greek Orthodox authorities and the U.S. State Department condemned the conversion as a disregard for Hagia Sophia’s Byzantine Christian heritage and a threat to religious pluralism.

How did Muslims and Orthodox Christians react to the reconversion?

Who was angered by the reconversion of Hagia Sophia in July 2020?

Critics highlight concerns that the reconversion privileges the Islamic past of the building over its Christian art and history, especially as many Byzantine mosaics depicting Christian figures have been covered, restricting their visibility for worshippers and visitors alike .

How did Muslims and Orthodox Christians react to the reconversion?

What political motivations influenced Erdogan's decision to reconvert Hagia Sophia?

Erdogan's decision was influenced by Turkey's Islamic resurgence.

Who was angered by the reconversion of Hagia Sophia in July 2020?

Many observe that the reconversion serves as a political tool by Erdogan to mobilize his conservative and religious voter base amidst domestic challenges such as electoral setbacks and economic difficulties, including the aftermath of a severe 2023 earthquake and high inflation.

What kind of domestic reaction did Erdogan's reconversion of Hagia Sophia receive?

Analysts suggest Erdogan’s action is part of a broader Islamo-nationalist agenda, aiming to reinforce Turkish sovereignty and identity while signaling defiance against international criticism, which the Turkish government has labeled as politically motivated and biased [36db8615-aa07-4391-a3f5-098dba27f295_1069312408; 76e3d61c-e991-43a2-8ebe-637114089506_291378229].

Title:

Content: >
December 9, 2021

Christian leaders look forward to Turkey's new law on religious foundations

This is an issue of vital importance for local Christian communities whose places of worship are entrusted to and managed by their governing bodies

Religious minorities in Turkey are looking forward to the increasingly Islamo-nationalist government making good its promise of outreach to non-Muslims by giving them freedom to establish and run their religious and social institutions.

The Turkish government is preparing to issue a new regulation on the administrative management of foundations linked to non-Muslim faith communities, which have been paralyzed for years by a legislative impasse that blocks the renewal of their governing bodies.

This is an issue of vital importance for local Christian communities such as Armenians and Assyrians, whose places of worship – many of them historic --, other real estate and public institutions are entrusted to and managed by foundations.

Burhan Ersoy, head of the state-run Directorate of the Foundations, has confirmed that the plan for the drafting of a new regulation concerning the elections for the assignment of offices within the foundations has come into being, Fides reported.

The draft of the text has been drawn up, taking into account requests and proposals from the various minority communities, and it is expected that the new rules, after obtaining government approval, would be implemented by April 2022.

The previous electoral regulation for the top management of foundations had been suspended in 2013, after the government chose to establish new procedures to make the management of real estate more functional and transparent.

This led to some confusion with representatives of the various minority communities unable to come to a consensus to either accept or reject the new electoral rules, Ersoy said.

The Syrian Orthodox Christian Süleyman Can Ustabaşı, current representative of the non-Muslim Foundations within the Assembly of Foundations, has said that the structure of foundations and their membership profiles had changed over time.

The Turkish government already had consultations with the representatives of religious minorities to resolve the dispute over board elections for their foundations.

But Ustabaşı now urges Turkish authorities to carry out another consultation with representatives of minority communities before the new text is to be implemented in 2022.

The legal status of the Foundations is still based on the Peace Treaty of Lausanne, signed in 1923 by Turkey and the Entente powers (British Empire, France and Russian Empire) victorious from the First World War.

The treaty guaranteed equality before the laws and the freedom to promote and manage "religious and social institutions" for non-Muslim communities in Turkey.

However, the state had seized properties run by these foundations and had to contend with litigation as these foundations claimed the rights guaranteed by the Treaty of Lausanne.

Also, starting from 1936, legislative provisions had allowed foundations of non-Muslim communities to acquire new properties. But in 1974, this guarantee was canceled and the state begun seizing assets acquired by these foundations.

Between 2013 and 2018 about 1,084 properties were returned to the foundations linked to non-Muslim communities, and 20 places of worship restored and given back to the foundations, according to official data.

Greek Orthodox Laki Vingas, in a speech published by the Armenian-Turkish newspaper Agos, said that the legislative deadlock on the question of the regulation of the foundations has had a negative effect on the life of the different ecclesial communities.

The block in the processes of renewal of the governing bodies of foundations had led to the expulsion of young people from the institutions linked to their communities, and also that many voluntary activities were "unfortunately interrupted".

Non-Muslim places of worship

Within the general Assembly of the Turkish Foundations are some 167 minority foundations. The Turkish Greek community has 77, the highest number of foundations. The Armenian community has 54 and the Jewish community has 19 foundations.

Turkish President Recep Tayyip Erdogan after a cabinet meeting held on October 25 announced that authorities had put on the agenda the question of the elections of the directorates of the foundations linked to religious minorities.

He also spoke of fundamental tools for the management of assets and resources destined for non-Muslim places of worship.

The issue of the foundations come at a time when Turkish authorities have expelled more and more Protestant Christians -- foreigners and Turkish converts-- on grounds they constitute a "threat to national security".

Turkey had also recently transformed museums into mosques, such as the Hagia Sophia and the Church of the Holy Saviour in Chora.

Both churches had been turned into museums after the end of the Ottoman Empire and the establishment of modern Turkey.

The Church of the Holy Saviour in Chora was built by the Byzantines in the 5th century. The Ottomans then turned it into a mosque after they captured Constantinople in 1453. And it remained a Muslim worship space until the end of the Second World War when it was transformed into a museum.

The same happened to the Hagia Sophia Museum in Iznik, and the high-profile reconversion of the Hagia Sophia Museum, Istanbul's most identifiable monument.

Many observers believe that President Erdogan, weakened internally by a bad economy and a lack of political perspective, is compensating with erasing part of the country's multiculturalism, aimed at shoring up the ranks of his Islamo-nationalist base.

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What political motivations influenced Erdogan's decision to reconvert Hagia Sophia?

Erdogan's decision was influenced by Turkey's Islamic resurgence.

Domestically, Turkish supporters regard the reconversion as a restoration of national pride and historical legacy.

How did Muslims and Orthodox Christians react to the reconversion?

What kind of domestic reaction did Erdogan's reconversion of Hagia Sophia receive?