The global healthcare system is facing a growing concern of medication shortages, with a record 323 drug shortages reported in 2024, affecting at least half a million patients.

The shortages have been tracked since 2001, and it has been found that sterile injectable generic drugs are particularly vulnerable to shortages, with over 135 drugs in short supply in the US, including chemotherapy.

The causes of drug shortages are complex and multifaceted, involving manufacturing problems, quality issues, and economic factors, such as high exchange rates and economic crises.

The lack of transparency in the supply chain hinders the response to shortages, and FDA inspections can lead to factory closures, further exacerbating the problem.

As a primary caretaker, it is essential to prepare for potential medication shortages by planning ahead and buying drugs and essential supplies in advance.

Checking the national drug shortage list can help prepare for potential medication shortages, and refilling prescriptions early can mitigate shortages.

Websites like GoodRX and RX Saver offer coupon assistance to help reduce prescription costs, and some programs can reduce prescription costs from $100 to $10.

Alternative medications or treatments can be used in place of prescribed medications if they become unavailable, and these alternatives can have the same active substance or a different active substance but the same therapeutic function.

The FDA provides data on prescription drug shortages, and their website is a valuable resource for staying up-to-date on the latest information.

The FDA also works with manufacturers to address shortages, which are often caused by production problems, and the National Association of Community Pharmacists tracks shortages.

The Ministry of Health and Welfare in Taiwan has established a drug shortage prevention center and implemented a new system to report Chinese medicine shortages.

The Taiwanese government has also established a coordination center for Chinese medicine shortage notification and plans to review and improve the supply chain.

In the US, the FDA has reported 111 drug shortages, and the agency monitors the supply chain to address these shortages.

The FDA also works with manufacturers to address shortages, which are often caused by production problems.

The American Society of Health-System Pharmacists tracks US drug shortages and advises the government on addressing these issues.

The FDA needs more power to access drug shortage information, and Congress requires manufacturer transparency on supply chains.

The White House has proposed $3.26-5.11 billion to address shortages, and the FDA needs more power to access drug shortage information.

The FDA has a list of currently deficient drugs, and ASHP tracks drug shortages in the US.

The FDA works with manufacturers to address shortages, and the National Association of Community Pharmacists tracks shortages.

The Utah Center provides drug information services, and the White House has proposed funding to address shortages.

The American Cancer Society has reported chemotherapy shortages, and the American Society of Health System Pharmacists advises the government on shortage issues.

In Italy, the Italian drug agency Aifa maintains a list of currently deficient drugs and provides updates on their website.

Aifa's list includes 3,197 drugs, with most having equivalent or therapeutic alternatives.

The FDA releases shortage status every two weeks, and a total of 22 Western medicine shortage reports were received.

The main reason for drug shortages is increased demand, according to the FDA.

The National Health Commission in China monitors drug shortages, and the State Medical Insurance Bureau tracks the national shortage list.

The National Drug Administration collects production supply data, and the Ministry of Industry monitors drug production supply.

The FDA reports major drug shortages, such as Adderall and liquid amoxicillin, which can be found on their website.

To stay informed about medication shortages, individuals can check the FDA website, ASHP website, or other reliable sources such as GoodRX and RX Saver.

Organizations such as the FDA, ASHP, and Aifa provide reliable information on medication shortages and alternatives.

The current medication shortage is affecting various drugs, including Ibuprofen, which is in short supply with 11,000 tons annual production, and is expected to ease within two months with government intervention.

Ibuprofen is an antipyretic and analgesic drug that is facing supply and demand contradictions, and the government is sending personnel to help local drug enterprises to guarantee raw material procurement and production capacity.

Aspirin, Paracetamol, and Lidocaine are also potentially deficient in the Russian market, while Fentanyl could become scarce, and Tamoxifen had a reported deficiency for oncological diseases.

The Ministry of Health has issued 44 permits to accelerate drug registration, and 470 thousand packages of Tamoxifen are in civil circulation, with an expected resolution timeline of about six months.

Other medications in short supply include Paroxetin Actavis 20 mg, Januvia 100 mg tablets, Smoflipid 200 mg/ml 100 ml N10, and Fraxiparine 2850 RÜ anti-Xa/0.3 ml, with expected resolution timelines ranging from January to June.

Alternative medications are available for some shortages, and patients are advised to consult their doctors for treatment continuation.

In the US, 323 drugs face severe shortages in Q1 2024, including diabetes drugs Ozempic and Mounjaro, chemotherapy drugs, and Amoxicillin for children.

The shortage of Mounjaro is due to unprecedented demand, and Lilly is ramping up production in 2024, while the White House has proposed $3.26-5.11 billion to address shortages.

The FDA needs more power to access drug shortage information, and Congress requires manufacturer transparency on supply chains.

In Taiwan, 22 drug shortages were reported between March 25 and April 4, including Ertapenem Sodium antibiotic, which is expected to withdraw from the market, and Yuanzhou Ginkgo Ning Tablets 40mg, which is in short supply.

The expected resolution timeline for Ertapenem Sodium shortage is 6 months, and 12 drugs have recommended alternative drugs.

Adderall is in short supply due to FDA limits and manufacturing issues, and the shortage is expected to resolve in April, but alternative ADHD medications are also in short supply.

The FDA limits active ingredients due to abuse risk, and patients are limited in how much Adderall they can get, which affects kids with ADHD in school.

Liquid amoxicillin is in short supply due to production delays, and the shortage affects treatment of ear infections and bronchitis.

The FDA lists all short supply drugs on FDA.gov, and production delays and component shortages cause drug shortages.

Ammoncillin antibiotic is in short supply due to high demand, but normal supply is expected to be restored within 2 weeks, and alternative medications are available.

In Russia, medicines for Parkinson's disease are in short supply, but drugs for bronchial asthma are now readily available, and thyroid drugs are no longer in short supply.

80% of vital drugs are domestically produced in Russia, and the localization of the domestic pharmaceutical industry is a priority.

Amoxicillin is in short supply among US drugmakers, including Hikma Pharmaceuticals, Teva Pharmaceuticals, and Novartis' Sandoz business, due to high demand.

The liquid amoxicillin form is most affected, with 19 products in shortage, and Hikma is curbing new orders to meet current contracts, while Teva expects back-ordered products to return by late October to early December.

Paxlovid is in short supply, with 180,000 courses available in 2021, but supplies are expected to improve in coming weeks, and Molnupiravir cuts hospitalization risk by about 30%.

Sotrovimab is in very short supply due to high demand, but supplies are expected to improve in coming weeks, and Paxlovid cuts hospitalization risk by nearly 90%.

Amoxicillin is in short supply, with only 70-80% of the usual supply available, and anticoagulant drugs, anti-allergic drugs, and blood pressure drugs are also in short supply.

Muscle relaxants for intubation during surgery are in short supply, and 34 drugs need to be replaced by other brands in large hospitals.

The shortage of medicines has extended from community pharmacies to hospitals, and the health insurance drug budget has not been adjusted for two years due to COVID-19.

The Russian market is experiencing a shortage of several medications, including Iodine, Aspirin, Paracetamol, Ibuprofen, Lidocaine, Fentanyl, and Phenobarbital.

Russia faces a shortage of about 100 drugs, with 97 drugs on the shortage list, including Immunoglobulin, Paracetamol, and the vaccine for diphtheria, pertussis, and tetanus.

Insulin and Children's Nurofen are also in short supply in Russia, with sanctions affecting medicine exports and disrupting supply chains.

The Ministry of Health in Russia has issued 44 permits to accelerate drug registration, and over 470 thousand packages of Tamoxifen are available.

In terms of specific medications, Paroxetin Actavis 20 mg is in short supply until February, while Januvia 100 mg tablets and Smoflipid 200 mg/ml 100ml infusion emulsion are in short supply until January and February, respectively.

Fraxiparine 2850 and 7600 RÜ anti-Xa, Augmentin Fruit 80 mg/11.4 mg/ml, and Zinnat 500 mg tablets are also in

The global healthcare system is facing a growing concern of medication shortages, with a record 323 drug shortages reported in 2024, affecting at least half a million patients.

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An Unexpected Catastrophe in the World ’ s Largest Country: The Complete Story of U.S. Drug Shortages
The deficit is at a record level.
According to data from the American Society of Health System Pharmacists and the University of Utah Drug Information Service, organizations began tracking drug shortages for the first time in 2001. Steady since 2021 – now reaching a record high of 323 drugs in the first three months of 2024.
Paul Abramowitz, CEO of the American Society of Health System Pharmacists, wrote in a blog post on Thursday: “It ’ s been a long time to end drug shortages, ” and wrote:“ All drug classes are vulnerable to shortages, some of the most worrisome shortages include sterile injectable generic drugs, including cancer chemotherapy drugs and emergency drugs stored in hospital vans and procedural areas. It is dangerous for doctors and patients. ”
In addition to the 32 chemotherapy drugs that are deficient, the five categories of drugs with the greatest deficiency include central nervous system stimulants, antimicrobials, hormonal agents, and intravenous fluids. [1] The Drug Deficiency Database maintained by the American Society of Health System Pharmacists and the University of Utah is based on voluntary reports from practitioners, patients, and others that have been confirmed by manufacturers. The U.S. drug is in short supply, because it captures broader effects on service providers and patients.
The crisis has lasted a year and a half.
More than half of the treatment shortages have lasted for more than two years, according to an analysis by health consultancy IQVIA, and the average shortage affects at least half a million patients, many of them elderly, according to the US Office of Health and Human Services under the Assistant Secretary for Planning and Evaluation, which shared its analysis with Congress in May.
Growing demand can play a role in drug shortages, as with the recent shortage of weight-loss drugs, but often manufacturing and quality problems, such as supply chain gaps and downtime, are the root cause. And varied.
But the American Society of Health System Pharmacists has “serious concerns ” about parts of this proposal, especially financial sanctions imposed on hospitals that lack the resources to comply with the recommendations, Abramowitz wrote:“ We all know that managing shortages is not enough and is not a sustainable solution to the worsening crisis, and there is still a lot of work to be done at the federal level to fix the root causes of drug shortages. ”
Why Shortage Occurs
Shortages can be caused by high demand, as with the recent shortage of weight-loss drugs, but this is not usually the main problem.
The FDA also blames manufacturing and quality problems, supply chain gaps, and downtime, and Dr. Emily Tucker, a drug shortage expert and an assistant professor of industrial engineering at Clemson University, says that when there is an indication of shortages, large health systems often also proactively place large orders, adding to the system ’ s stress.
“I don ’ t blame anyone.
“When I talk to all the stakeholders – whether it ’ s wholesalers, manufacturers, or the government – everyone wants this problem to end, ” she said.
Lack of transparency
Dr. Julie Grallo, chief medical officer and executive vice president of the American Society of Clinical Oncology, told the House Committee earlier that the shortage puts providers in a terrible position: “The drug shortage crisis is forcing providers to make impossible choices, and it is also hindering the development of new drugs. Health drugs are purchased only on a price basis, and manufacturers do not have to disclose the source of their acquisition of the ingredients.
The shortage of this generic chemical drug came due to the closure of one factory in India that manufactures the active ingredient after a surprise FDA inspection found “significant quality issues, ” says Jarallo:“ We didn ’ t know, and there was no transparency regarding the company ’ s supply of the majority of active pharmaceutical ingredients to all manufacturers across the board.
Knowing this in advance, we could have responded much faster, ” Dr. Steven Schundlemeyer, director of the PRIME Institute of the University of Minnesota School of Pharmacy, which focuses on economic and management issues, told the committee that as with defense contractors in the United States, New Zealand requires manufacturers to disclose their suppliers, and that information is required.
Easily accessible in the database.
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The shortages have been tracked since 2001, and it has been found that sterile injectable generic drugs are particularly vulnerable to shortages, with over 135 drugs in short supply in the US, including chemotherapy.

The causes of drug shortages are complex and multifaceted, involving manufacturing problems, quality issues, and economic factors, such as high exchange rates and economic crises.

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Content: Crowding citizens in front of the ambulance pharmacy reveals the extent of suffering …
6.
The suffering of poor patients is due to the lack of medicines.
Where the pharmaceutical market has been suffering for several consecutive months from a severe shortage in many varieties.. Which prompted citizens to crowd in front of the ambulance pharmacy in long queues to buy those shortcomings after they disappeared from all pharmacies..
Hustle...
Chaos...
Hundreds of men and women crowded in long queues that extend for several hours.. This is the scene in front of the ambulance pharmacy in the center of the country. People with chronic diseases of sugar, pressure, heart, nerves and colon became their only hope to find essential drugs for them in the pharmacy.. The absence of these drugs does not only expose them to more pain but may expose them to death.. They can not do without them..
The drug shortage crisis.
It is not a new crisis, but it has been repeated many times during the previous term of Minister “Khaled Abdel Ghaffar ”.. Instead of trying to solve the crisis, the government is going against the trend, where the Deputy Prime Minister and Minister of Health Dr.“ Khaled Abdel Ghaffar ” in statements after the government statement to parliament to the need to increase the prices of medicine in Egypt because it is the cheapest in the world and sold abroad by 50 times. According to the data of the Medbelle global platform for health care and funded by the European Fund for Regional Development in 2021, Egypt is ranked ninth in the list of cheapest countries in the world in the sale of medicine, and did not come in the first place as mentioned by the minister
Despite the repeated statements of the Prime Minister and the Minister of Health to resolve the crisis and provide the missing medicines, and despite the government ’ s repeated talk about the localization of the pharmaceutical industry in Egypt, the reality is quite the opposite.
There are a number of terrible complaints about the lack of medicine in public hospitals and pharmacies, including a collective complaint from the patients of the university hospitals in Assiut Governorate of the lack of availability of drugs and the absence of dye injections, which puts their lives at risk. Although the patients filed a complaint to the governor two weeks ago, but to no avail. The long queue of two or three hours to win a box of insulin Maxtard despite the increase in the price from 60 pounds to 93 pounds confirms the extent of suffering experienced by patients. Also, the disappearance of Indoxan injections used in chemotherapy sessions threatens oncology patients, where thousands of patients in oncology institutes and hospitals suffer from delayed chemotherapy sessions for lack and disappearance of Indoxan injection. The right to medicine, but the crisis still exists.
There is also a shortage of many drugs, including blood thinners and clots solvents, drugs for the treatment of cancerous tumors, multiple sclerosis drugs, drugs for the treatment of liver diseases, drugs for stomach ulcers and blood pressure, drugs for sinuses, heart and thyroid diseases, dozens of types of analgesics, antibiotics and vitamins, as well as anesthetics used in anesthesia and solutions in public hospitals. Subsidized children, which was exploited by the mafia of the black market to raise prices to double the original price of milk can up to 500 pounds..
All types of treatments for epilepsy, depression, obsessive-compulsive disorder, phobias and hyperactivity disease are still unavailable due to the lack of import of raw materials.
Health Insurance Patients
The crisis is not limited to hospitals and pharmacies only, but the branches of health insurance suffer from a large shortage of medicine and also medical supplies, which led to the closure of the operating rooms in the branches of insurance in the province of Beni Suef..
In the health insurance clinics in Cairo and Giza, many of those who frequent these clinics complained that they come from 7 am to reserve their roles in order to dispense their medicines and end up sitting in the pharmacy waiting for the pharmacist who dispenses them some of them, and the rest of their medicines are separated in new prescriptions to be dispensed from the insurance pharmacies, if any. Blood thinners and thrombotic solvents, some pressure medications, multiple sclerosis medications, stomach ulcer and thyroid medications, sugar, antibiotics, vitamins, Parkinson ’ s medications, and hyperactivity protocol.
Many cases complained of the lack of their medicines, which they have been dispensing for years.. And they were dispensed periodically every two months for a year after the approval of the Drug Committee to dispense those medicines, including a special medicine liquidity imported medicines, and patients with diabetes and blood diseases were their complaint that any imported medicine and its price expensive requires the highest approval of a committee in the Council of Ministers..
Although patients have been dispensing the same medication for several years, this complaint is frequent from universal health insurance patients.
Detention of raw materials
Dr. Ali Auf, head of the pharmaceutical division of the Federation of Chambers of Commerce, said that the reason for the worsening of the shortage of medicines is the detention of raw materials in ports, pointing out that there are about 1000 items that are not available.
Exchange rate
Mahmoud Fouad, Executive Director of the Right to Medicine Association, said that the aggravation of the crisis is due to the companies stockpiling medicines in anticipation of higher prices, explaining that the crisis began about two years ago due to the shortage of raw materials as a result of the high exchange rate and the inability of companies to provide dollar materials to import raw materials.
Fouad stressed that there are more than 1000 drugs whose prices rose during the past year by rates ranging from 25% to 60%, pointing out that the increase reached during the current days to 60% for the local and 80% for the importer.
Fouad described the statements of the Minister of Health about the price of Egyptian medicine as being 50 times lower than abroad as shocking, pointing out that there was a successive movement of prices from the Drug Pricing Committee of the Egyptian Drug Authority starting in 2023, which resulted in the movement of about 1,000 varieties.
He explained that Egypt suffered during the last two years from the phenomenon of medicine shortage due to the shortage of imported raw materials as a result of the economic crisis and the fluctuation of the exchange rate … and the crisis affected items considered life-saving.
Fouad stressed that drug sales in Egypt reached about $3 billion a year in 2023 without the sales of the armed forces and the interior and tenders of the Ministry of Health, which means that Egypt is considered the largest market in the region.
Unfair pricing system
He explained that Egypt had been subject to the pricing of medicines for 10 years according to the decision of the Minister of Health under the system of "lower pricing for neighboring countries" and then the pricing was according to the decision 413 of 1991, which is "calculating the cost and profit margin for companies and distribution and then pharmacies" according to the compulsory pricing that began in 1988.
He explained that the pricing is according to the cheapest price in the reference countries identified by the World Health Organization (WHO) in 36 countries to guide their prices and the minister to take them or not, pointing out that these countries are the major industrial countries and have comprehensive health insurance laws, which Egypt lacks.
Fouad added that this system in pricing is unfair as medicine has become subject to market mechanisms, supply and demand and suspicions of monopoly, the price is controlled by the policy of supply and demand, which makes medicine a commodity sold to those who can, especially since there are more than millions of Egyptian people not participating in the health insurance system, which only 63% of citizens participate.
Fouad pointed out that Egypt has about 17 officially registered medicines, 90% of which are manufactured, 176 companies that own factories, 7 business sector companies, 22 branches of foreign companies and 1,200 commercial companies that do not own a factory.
He stressed that the crisis of medicine shortage and successive rises will make the Egyptian citizen groaning and unable to bear it.
Fouad warned of the danger of the expected increases in drug prices during the coming period.

The lack of transparency in the supply chain hinders the response to shortages, and FDA inspections can lead to factory closures, further exacerbating the problem.

As a primary caretaker, it is essential to prepare for potential medication shortages by planning ahead and buying drugs and essential supplies in advance.

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The first stop to the pharmacy to buy drugs, "Sorry, all the anti-fever drugs have been sold out." The clerk shook his head and said.
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In the second stop, I went to a supermarket to buy daily food, went to several supermarkets, many shelves were cleaned up, including oil, toilet paper, boxed milk, etc., and only managed to buy instant noodles and a lot of white rice.
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Checking the national drug shortage list can help prepare for potential medication shortages, and refilling prescriptions early can mitigate shortages.

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Content: Prescription drug shortages lead to higher prices

Reporter: Andryanna Sheppard
Published: Updated:
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Millions of people in the United States depend on prescription drugs to manage pain, treat medical conditions, and even to help them stay alive. However, the country’s drug shortage is making it hard for some people to get the medication they need or pay for the drugs that are available.

Federal Drug Administration data shows 90 percent of prescriptions in the US are for generic drugs. According to the National Institutes of Health, most prescription drugs involved in shortages are generic options.

There are currently more than 250 medications on the nation’s prescription drug shortage list, according to the American Society of Health-System Pharmacists. The organization says 2023 marked the worst year for shortages in about a decade.

Jessica Kahn’s two sons were diagnosed with ADD.

“I would say tricky, tricky to navigate,” Kahn described.

For the past year, Kahn said getting their medication has been frustrating.

“I have my list of all the pharmacies. I’ve even driven all the way up north to Walgreens or a CVS, some random place to go pick up a kids’ prescription,” Kahn added.

According to the FDA, prescription drug shortages are often linked to manufacturing and quality problems, delays, and discontinuations. Two drugs used in chemotherapy, Adderall, lidocaine, and amoxicillin are just a couple of the prescription medications on the shortage list.

When drug supplies are low, prices tend to increase. According to the US Department of Health and Human Services, there is a 16.6 percent increase in the price of drugs involved in a shortage. And in some cases, alternative drugs were priced at least three times higher.

“You got to be very conscientious that it might not be available and that it is not an option,” Kahn advised. “No matter how many places you call, it’s not there.”

Beating the prescription drug shortage

Health experts offer these tips:

  • Check the national drug shortage list for your medication and possible alternatives.
  • Don’t wait until your prescription is almost gone to refill it.
  • Check other pharmacies for availability and if you can’t find the generic version, look for coupons or programs that offer payment help. Some patients have reported that they receive additional help to reduce some prescription costs from $100 to $10, it’s not allowed if you are already on Medicare.
  • Websites and apps like GoodRX, RX Saver and WellRX can help you find the cheapest place that has your medication and coupons for it.

Contributors to this news report include: Lindsay Dailey, Producer; Bob Walko, Editor

Copyright ©2024 Fort Myers Broadcasting. All rights reserved.

This material may not be published, broadcast, rewritten, or redistributed without prior written consent.

Websites like GoodRX and RX Saver offer coupon assistance to help reduce prescription costs, and some programs can reduce prescription costs from $100 to $10.

Alternative medications or treatments can be used in place of prescribed medications if they become unavailable, and these alternatives can have the same active substance or a different active substance but the same therapeutic function.

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Health: No shortage of thyroid drugs and genetic diseases
Dr. Hossam Abdel Ghaffar, the official spokesman of the Ministry of Health, revealed the reality of the lack of medicines and the difference between alternative and similar medicines.
According to the World Health Organization (WHO), the lack of medicines means that patients cannot be provided with a drug for which there is no analogue or alternative.
Abdel Ghaffar said that similar drugs are drugs that contain the same active substance in the same composition and in the same way of administration, while alternative drugs are drugs that perform the same therapeutic function but with a different active substance.
All summer medicine is available.
Abdul Ghaffar explained that all medicines for summer diseases are available, where they are manufactured and produced locally, while the thyroid medicine is available and contains the same active substance, stressing that there is no shortage of medicines for genetic or rare diseases.
In case of shortage of medicines, you can contact the Egyptian Drug Authority hotline 15361.

The FDA provides data on prescription drug shortages, and their website is a valuable resource for staying up-to-date on the latest information.

The FDA also works with manufacturers to address shortages, which are often caused by production problems, and the National Association of Community Pharmacists tracks shortages.

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Content: US supply chain crisis continues, FDA points to 111 drug shortages
Global Social Hotspot 16: 35 2021 / 12 / 05
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The supply chain crisis in the United States continues, and many goods are facing shortages.
The US media said that the US pharmacies have a number of critical prescription drugs in stock. The US Food and Drug Administration (FDA) pointed out that about 111 drugs are out of stock in the United States. The FDA stressed that it will continue to take measures to monitor the supply chain.
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The Federal Reserve warned on Wednesday that large parts of the United States had begun to be affected by supply chain disruptions and labor shortages last month.
According to the FDA website, 111 drugs are out of stock in the United States, including the heart disease drug digoxin injection, the chemical drug Dacarbazine and some antibiotics.
The authorities say there are many reasons for the shortage, including production problems, quality problems, drugs and even the suspension of production.
According to the FDA, about 80% of the manufacturers of active pharmaceutical ingredients are located overseas, and the manufacturers have provided the FDA with most of the drug shortage information.
The Administration will also work closely with these manufacturers to address the drug shortage.
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Long Island Newspaper Newsday quoted Tom D'Angelo, president of the New York State Association of Pharmacists, as saying the shipping of a large number of medicines, including those for common blood pressure and for the treatment of colds and flu, was blocked.
Because of supply chain problems, the owner of a New York drugstore said there were fewer brands for some drugs, including Ibuprofen.
The National Association of Community Pharmacists (NCPA) released a survey last month that found that most non-chain pharmacies are struggling to fill employee vacancies and cope with supply chain disruptions.
Sixty percent of pharmacies surveyed said they were dealing with supply chain disruptions, and nearly 70 percent said it was difficult to fill staff vacancies.
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The Ministry of Health and Welfare in Taiwan has established a drug shortage prevention center and implemented a new system to report Chinese medicine shortages.

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Chinese medicine shortage for the first time, the Ministry of Health and Welfare announced the new system as soon as April
2023 / 3 / 12 12: 14 (Updated 3 / 12 12: 52)
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The Ministry of Health and Welfare has organized a drug shortage prevention center to bring the drug shortage treatment mode to the ministerial level.
Minister of Health and Welfare Xue Ruiyuan said on the 12th that the plan is to officially report the shortage of Chinese medicine for the first time.
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The Ministry of Health and Welfare plans to organize a drug shortage prevention center to pull the drug shortage treatment mode to the ministerial level, Minister Xue Ruiyuan said today, planning to officially report the shortage of Chinese medicine for the first time, so as to facilitate the central government to immediately respond to the dispatch, the new system is expected to hit the road as soon as April.
This morning, Xue Ruiyuan attended the National Federation of Traditional Chinese Medicine of the Republic of China 2023 93rd National Medical Day 15th Taipei International Traditional Chinese Medicine Academic Forum. In his speech, he said that in the future, Chinese medicine shortage also needs to be reported, so as to achieve real-time control, immediate response, schedule import or coordinate with manufacturers to increase production.
Hsueh Jui-yuan says that in the past, there was no clear mention of Chinese medicine in the Pharmacy Act, because in the past it was mainly handled by the Food and Drug Administration, and the scope would be narrower, mainly targeting Western medicine shortages, but this time the Coordination Center for Chinese medicine shortage notification was brought to the ministerial level, so Chinese medicine shortages were also brought in.
Xue Ruiyuan said that in the future, Chinese medicine practitioners and the Chinese medicine community as long as they find a shortage of drugs, they can report it, and today officially announced the new system, which was originally in operation, and now needs to be added to the system to report the shortage of Chinese medicine.
In addition, Xue Ruiyuan said that the Chinese medicine supply chain is also an issue that Taiwan needs to review, from raw materials to final pharmaceutical products. He hopes to cooperate with the Council of Agriculture and the Ministry of Economic Affairs to establish more domestic production supply chains. Built within 2 years. (Editor: Chen Renhua) 1120312
Recently, Western medicine shortage frequently, the Ministry of Health and Welfare organized a drug shortage prevention center, will be the lack of drug treatment mode to the ministerial level, Minister of Health and Welfare Xue Ruiyuan (middle) said on the 12th, planning for the first time to officially report the lack of Chinese medicine, is expected to be on the road as soon as April.
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The Taiwanese government has also established a coordination center for Chinese medicine shortage notification and plans to review and improve the supply chain.

In the US, the FDA has reported 111 drug shortages, and the agency monitors the supply chain to address these shortages.

The FDA also works with manufacturers to address shortages, which are often caused by production problems.

The American Society of Health-System Pharmacists tracks US drug shortages and advises the government on addressing these issues.

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Content: Meitu
The first quarter of the United States serious drug shortage 323 drugs urgent cancer patients also have to be diverted and rationed!
CHU HENG NETWORK NEWS CENTER 2024-04-16 10: 42
According to the latest data from the American Society of Health System Pharmacists (ASHP) and the Utah Center for Drug Information Services, a total of 323 drugs in the United States were in severe shortages in the first quarter of this year, surpassing the record of 320 in 2014.
Among the drugs affected are the widely used diabetes drugs Ozempic and Mounjaro, the allergy treatment drug adrenaline, the common antibiotic amoxicillin for children, chemotherapy drugs and injections commonly used in hospitals in intensive care.
ASHP CEO Paul Abramowitz said in a statement that almost all categories of drugs are facing shortages, with non-patented sterile injectable drugs, including cancer chemotherapy drugs, and emergency drugs stored in hospital emergency vans and operating areas, the shortage of such drugs is the most worrying.
According to the American Cancer Society, chemotherapy is one of the top five drugs most affected by the shortage, which threatens to have a devastating impact on patients, and some hospitals and clinics say doctors have had to divert patients to ration their medications because of a shortage of some chemotherapy drugs.
In addition, ASHP noted that the continued nationwide shortage of ADHD drugs is “a problem for clinicians and patients. ”
The shortage of popular drugs is even more acute, with Mounjaro, the diabetes drug known as the “slimming pill ”, already in dire straits.
In response, Lilly said that the “unprecedented surge in demand ” for Mounjaro and its similar drug Zepbound has led to a shortage in the market, which the company is struggling to cope with.
Lilly is ramping up investments to boost production at Mounjaro and Zepbound in the second half of 2024.
The company said it expects intermittent supply disruptions in the near term due to unprecedented demand.
How to cure the drug shortage
The last major “drug shortage ” in U.S. history occurred in 2014, and it has only been alleviated in the years since.
Since 2021, the drug shortage situation seems to be increasing, and scholars in the field of medical health and economics in the United States believe that the reason for most drug shortages in the United States is the fragmentation of the drug supply chain.
The White House this month proposed spending between $3.26 billion and $5.11 billion over the next decade to help address the nation ’ s drug shortage.
The bill requires approval and funding from the U.S. Congress.
U.S. researchers and policymakers believe that a complete solution to the “drug shortage ” may require changes to the business model of the U.S. pharmaceutical industry, including measures to increase the price of generic drugs to attract more drug manufacturers.
Policymakers recommend giving the FDA more power to access more information about drug shortages and impending shortages.
Currently, the FDA relies primarily on phone calls to manufacturers asking if they can increase their supply to understand the situation.
The American Society of Health System Pharmacists said it is working with the federal government to advise the government on measures to address the drug shortage, including that Congress should require manufacturers to be more transparent on any supply chain issues and encourage more diversity in supply chains.
According to Abramowitz, “The federal government still has a lot of work to do to fundamentally address drug shortages, and the American Society of Health System Pharmacists will continue to engage regularly with policymakers to guide them in drafting and passing new legislation to address drug shortages and continue to advocate vigorously for proven solutions on behalf of our members. ”

The FDA needs more power to access drug shortage information, and Congress requires manufacturer transparency on supply chains.

The White House has proposed $3.26-5.11 billion to address shortages, and the FDA needs more power to access drug shortage information.

The FDA has a list of currently deficient drugs, and ASHP tracks drug shortages in the US.

The FDA works with manufacturers to address shortages, and the National Association of Community Pharmacists tracks shortages.

The Utah Center provides drug information services, and the White House has proposed funding to address shortages.

The American Cancer Society has reported chemotherapy shortages, and the American Society of Health System Pharmacists advises the government on shortage issues.

In Italy, the Italian drug agency Aifa maintains a list of currently deficient drugs and provides updates on their website.

Title:

Content: Home Health Drug shortage. Palù (Aifa): “There is no real alarm”. Anti Covid vaccines: “60-70% over 60 did not receive the fourth dose, it is good that he does”

Drug shortage. Palù (Aifa): “There is no real alarm”. Anti Covid vaccines: “60-70% over 60 did not receive the fourth dose, it is good that he does”

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“The fourth dose is not only 90% effective in preventing mortality but also in limiting the spread of the virus”, recalled the president Aifa speaking to SkyTg24. As for the shortage of medicines: “The shortage is an objective fact, but Italy is one step ahead of the others. There is no real alarm, also because there is coverage provided by equivalent medicines. Communication between doctors and pharmacists needs to be improved “.

12 GEN

“There has been a significant drop in the resumption of vaccinations. Among people over the age of 60, 60-70% did not make the second booster, the so-called fourth dose”.

This was stated by the president of the Italian drug agency (Aifa) George Paluhost of Sky TG24.

“It is good to have the second vaccination booster – recalls Palù – as shown by a study on prisoners published in Nature Genetics: the fourth dose is not only 90% effective in preventing mortality but also in limiting the spread of the virus”. As for therapies, “we have very effective antivirals such as remdesivir, which is given in infusion; while molnupiravir is slightly less effective but China is buying it because it is easily taken” in pills. And then, he continues, “there is paxlovid, which unfortunately interferes with some drugs and general practitioners who can prescribe it are a bit hesitant, but Aifa has taken action by publishing a table on the site with indications of possible drug-drug interactions”.

As for the shortage of medicines, the president of Aifa explains: “The shortage is an objective fact, but Italy is one step ahead of the others. There is no real alarm, also because there is coverage provided by equivalent medicines. However, improvements need to be made communication between doctors and pharmacists”.

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Palù then reported that Aifa maintains a constantly updated page of currently deficient drugs, which can be regularly visited by doctors, professionals and pharmacists. A list that today includes 3,197 drugs. “In reality – explains Palu’ – most of them are drugs that are no longer produced or are no longer on the market, but for almost all there is an equivalent or a therapeutic alternative. Of the total, 300 are somewhat missing because they are imported medicines – said Palù – but only 30 of these are truly essential because they do not find a counterpart produced by an Italian industry”. Drugs used in operating rooms, but also anti-inflammatories, cortisones, muscle relaxants and antibiotics of which, clarifies the president Aifa, “we always have valid alternatives”.

Despite this, Palù specified, “Minister Schillaci did very well to order the checks. People go to the pharmacy and don’t find the medicines they were used to, the doctor still prescribes the old medicines, there has been a request from so-called stakeholders, the minister was concerned. And I believe that what will come out of it will be more information”.

“So I want to say that perhaps this is not perfect communication. An important dialogue is needed between doctors, pharmacists and trade associations, and above all doctors who are knowledgeable and trained to access this information which is constantly available” Palù concluded.

January 12, 2023
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Aifa's list includes 3,197 drugs, with most having equivalent or therapeutic alternatives.

The FDA releases shortage status every two weeks, and a total of 22 Western medicine shortage reports were received.

Title:

Content: The first two weeks of the drug shortage platform announced 22 new lung cancer drugs "Rothko Capsules" will be imported into the project
▲ It is recommended to use 12 substitutes for the missing drug items, a total of 10 drug licenses.
(Photo / taken from the website of the Food and Drug Department)
Journalist Yen Yun-chen / reporting from Taipei
The Ministry of Health and Welfare announced today (12) the shortage of 22 drugs in the first two weeks of the list, including the lung cancer new drug "Rosick 200 mg capsule" due to the shortage of foreign raw materials, has coordinated the original company to send foreign packaged drugs to Taiwan, and will be imported by project.
The Food and Drug Administration of the Ministry of Health and Welfare has set up a "Drug Supply Notification Processing Center" to integrate six types of drug platforms, including Western medicine, Chinese medicine, rare disease drugs, children 's difficult to obtain drugs, public vaccines and infectious diseases drugs.
[Advertisement] Please continue reading...
Before the opening of the platform, the Food and Drug Administration of the Ministry of Health and Welfare issued a letter to medical institutions and pharmacies on March 24, re-statistics on the shortage of various brands, and announced the status of processing every two weeks, and released the first survey results today (12).
▲ A new lung cancer drug, Roseke Capsules, has been launched for public consultation.
(Photo / taken from the website of the Food and Drug Department)
From the public information of the platform, it can be seen that from March 24 to April 4, a total of 22 reports of shortage of Western medicines were received, of which 7 were investigated without shortage, 12 had alternative medicines, 1 had been restored to supply, 1 had no alternative medicines to start the open request, and 1 was under processing.
In an interview with the media, the director of the Food and Drug Department, Yang Po-wen, pointed out that half of the 22 items were reported by the manufacturer, and the other by the hospital or pharmacy, and the reason for the notification was that the normal supply of the products was not expected.
Yang Po-wen points out that in terms of the shortage of drugs, the main reason for the shortage of drugs is the increase in demand for drugs, which has led to a shortage of drugs on the supply side, or the shortage of drugs caused by production problems.
The Food and Drug Administration (FDA) will look for alternative medicines according to the shortage of drugs. For example, Taiyu Pharmaceuticals “Lok Shin Ping Capsules 30mg ” is recommended to replace with the same ingredient. However, the lung cancer drug“ Rossik 200mg Capsules ” is a new drug. Project input.
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The main reason for drug shortages is increased demand, according to the FDA.

The National Health Commission in China monitors drug shortages, and the State Medical Insurance Bureau tracks the national shortage list.

Title:

Content: 【 Printing 】
2023 shortage of drugs reported information has been fully dealt with
Related LINKS http: / / www.CRNT.com 2024-03-14 15: 33: 32
Beijing, March 14 / Xinhua News Agency reported that the reporter learned from the National Health and Health Commission on the 13th, the national, provincial, municipal and county four shortage drug classification system gradually improved and effective operation, 2023 shortage drug reporting information has been fully addressed, and the temporary import work of clinically urgent drugs is done.
It is understood that in the near future, the national and provincial shortage of drug supply guarantee work will discuss the mechanism of various units to ensure the supply of stable prices as the focus, and continue to improve the classification of shortage of drugs to deal with the ability to deal with, multi-dimensional improvement of shortage of drug information monitoring.
The National Health and Health Commission relies on the national public medical and health institutions shortage of drug information direct reporting system and other monitoring conditions to carry out monitoring and early warning and regular reporting.
The State Medical Insurance Bureau continuously monitors the national shortage list of drugs and clinically necessary drugs that are vulnerable to shortage, focusing on the abnormal high prices and distribution data of the listed drugs.
The National Drug Administration continues to collect information on the production supply and shutdown reports of shortage of pharmaceutical products.
The Ministry of Industry and Information Technology relies on the shortage drug production supply monitoring and early warning platform to carry out dynamic monitoring and analysis.
The Ministry of Commerce organized some large pharmaceutical wholesale and retail enterprises to pay close attention to the supply and demand situation of pharmaceutical products.
At the same time, the whole chain guarantees the stable supply of shortage drugs.
The National Drug Administration continues to promote the review and approval of national shortage drug list varieties, and carries out the basic information labeling and data management of shortage drugs.
The State Medical and Health Insurance Bureau fully implements the policy of online procurement of shortage drugs, and explores the centralized procurement of shortage drugs.
The Ministry of Industry and Information Technology continues to support the construction of centralized production bases for small varieties of drugs, and establish regular shortages of drugs at the central and local levels.
The Ministry of Ecology and Environment takes flexible enforcement action to help enterprises rectify the situation in a timely manner if the environment of the enterprises involved in the production of pharmaceutical raw materials or preparations violates the law.
The SASAC of the State Council continues to promote state-owned enterprises to fulfill their social responsibilities in the supply of shortage drugs and play the function of "cistern".
The National Post Office continues to promote the construction of a comprehensive postal service platform, supporting the postal group to give full play to its network advantages and continuously improve its medical distribution service capabilities.
In addition, strengthen the enforcement of illegal acts.
The General Administration of Market Supervision investigates and punishes illegal acts such as monopoly in the field of pharmaceutical products according to law, and plays a warning and education role in major typical cases.
The General Administration of Taxation further increased the investigation and punishment of tax violations by some pharmaceutical enterprises, and standardized the tax order in the pharmaceutical field.
According to the clues of the problem and illegal facts, the National Medical Insurance Bureau talked about the relevant pharmaceutical companies to reduce the level of drug prices involved, and block the chain of benefits of manufacturing shortages and monopoly price increases.
【 Printing 】
Related News:

The National Drug Administration collects production supply data, and the Ministry of Industry monitors drug production supply.

The FDA reports major drug shortages, such as Adderall and liquid amoxicillin, which can be found on their website.

Title:

Content: 2 major drugs are in short supply, FDA says. Both are widely prescribed to children.

NEW!

Drug shortages continue in the U.S., even as the COVID-19 pandemic nears the end of its third year.

Two drugs commonly prescribed to children — Adderall and liquid amoxicillin — recently joined the list, the Food and Drug Administration says.

The FDA announced last month that it was talking to manufacturers about a shortage of Adderall, the combination drug of amphetamine mixed salts used to treat attention deficit hyperactivity disorder.

Parents are also discovering liquid amoxicillin — an important antibiotic used to treat bacterial infections — is in short supply, according to the FDA. It added the oral solution of the antibiotic to its list of drug shortages on Oct. 28.

Both drugs are widely used by children as well as adults. The amoxicillin shortage comes at a vulnerable time, as we enter cold and flu season and U.S. hospitals continue to fill with respiratory infections. Amoxicillin is often used to treat ear infections and bronchitis.

The reason for the shortages? The FDA didn’t immediately respond to a request for comment Thursday. However, the agency cited a few factors on its website, including quality and manufacturing issues.

“There have been other reasons such as production delays at the manufacturer and delays companies have experienced receiving raw materials and components from suppliers,” the agency says. “Discontinuations are another factor contributing to shortages.

“FDA can’t require a firm to keep making a drug it wants to discontinue. Sometimes these older drugs are discontinued by companies in favor of newer, more profitable drugs.”

For a list of all drugs currently in short supply, visit FDA.gov.

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Spencer Kent may be reached at skent@njadvancemedia.com.

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To stay informed about medication shortages, individuals can check the FDA website, ASHP website, or other reliable sources such as GoodRX and RX Saver.

Organizations such as the FDA, ASHP, and Aifa provide reliable information on medication shortages and alternatives.

The current medication shortage is affecting various drugs, including Ibuprofen, which is in short supply with 11,000 tons annual production, and is expected to ease within two months with government intervention.

Title:

Content: Observers reported on the 21st, the mainland Kangzhi pharmaceutical industry on the 20th in the Shenzhen Stock Exchange interactive easy release "Kangzhi Pharmaceutical Co., Ltd. investor relations activity record table", for the "terminal residential supply situation relief time" answer: the current situation, is expected to ease within two months, with the intervention and regulation of the mainland country, it is possible to advance.
There are two domestic raw material pharmaceutical manufacturers of ibuprofen in the mainland, and the annual production capacity is estimated to be about 11,000 tons.
The following is the main content of the questions and answers related to the sales of mainland drugs:
Q: Now there is a vacancy situation everywhere, the company now sells cold medicine to the outside world, including the production and the pace of outward shipment?
A: Recently, from the gradual release of Guangzhou, to the release of the "new ten" on December 7, the market for the whole market for antipyretic and analgesic drugs has grown rapidly. Sales in December increased significantly compared with January to November this year.
At present, the main focus is on antipyretic analgesia and anti-cold, the current market has a certain contradiction between supply and demand, but it is not serious...
However, due to the recent controversy around the mainland, especially the stockpiling of antipyretic drugs and panic, there has been a short shortage of goods and other situations, and the latter was quickly resolved.
Q: From the perspective of the industry, the current degree of market shortage, and the expected time to alleviate the shortage?
Is the production department of relevant enterprises directly taken over by the government, and will it be medical institutions and pharmacies in the future or other forms?
A: According to the China National Working Group on Disease Control and Prevention issued on the 14th, local government organizations are required to help manufacturers solve all problems in the production process, including the procurement of raw materials, production capacity, and technological upgrading, in order to fully guarantee the supply of the market.
At the same time, the government requires all levels of government to send personnel to local enterprises related to the four types of drugs.
The list of important protection enterprises designated by the mainland government for anti-epidemic drugs is that the brand strength and influence of enterprises are better, the second is that the production capacity and supply capacity are relatively strong, the third is that the reputation is relatively good, and the fourth is that the product quality is guaranteed.
Can quickly ensure that the staff stationed in the first batch of important protection enterprises, can help enterprises to solve various problems, especially when facing the contradiction of raw materials problems, governments at all levels in the name of the government and raw materials enterprises to communicate to help enterprises quickly solve.
For the future market trend of drugs, the forecast needs to be updated in a timely manner.
Because the current market four types of drugs are still scarce, because the population base is too large, although one or two tablets may be able to solve the fever, but people are generally a box or a bottle to buy, so still can not meet the needs of more than a billion people.
Q: What is the difference between the research and development of children ’ s drugs and the research and development of adult drugs?
A: First, you must be familiar with the characteristics of the whole child drug, second, you must know the basic principles of child drug treatment, and third, you can determine the rational use of children's commonly used drugs.
Then you need to know the cause of children's fever and how to deal with it, such as children's fever, ultra-high fever, affecting sleep, memory, poor mobility, coma, convulsions, etc., to find the cause.
The basic principle is to first clarify the purpose of child hypothermia, the child's anal temperature is greater than or equal to 39 ° C, or the temperature of the mouth is greater than 38.5 ° C, or the temperature of the underarm is greater than 38.2 ° C, which can fully determine that the child has begun to heat.
At present, the four principles of "safe, effective, economical and appropriate" for treatment in mainland China are basically in line with the current principles of drug economics.
Q: How long will the supply of terminal residents be in short supply?
A: At present, this situation is expected to be alleviated within two months, and with the intervention and regulation of the state, it is possible to advance.
There are two domestic raw material pharmaceutical manufacturers of ibuprofen in mainland China, and the annual production capacity is estimated to be about 11,000 tons.
# Children 's Drugs # Unblocking # Drugs # Markets # Coronavirus

Ibuprofen is an antipyretic and analgesic drug that is facing supply and demand contradictions, and the government is sending personnel to help local drug enterprises to guarantee raw material procurement and production capacity.

Aspirin, Paracetamol, and Lidocaine are also potentially deficient in the Russian market, while Fentanyl could become scarce, and Tamoxifen had a reported deficiency for oncological diseases.

Title:

Content: Advertisement
NEWS
The Ministry of health included iodine, aspirin and paracetamol in the list of potentially deficient drugs
Today at 19: 58
The Interdepartmental Commission of the Ministry of Health included 97 items in the list of drugs that could potentially become scarce in the Russian market.
This is reported by “Kommersant ”.
The list includes iodine, ibuprofen, acetylsalicylic acid (aspirin), lidocaine, paracetamol, fentanyl, phenobarbital (the main component of valocordine and corvalol) and other drugs.
With regard to these drugs, the Government will take measures to ensure that they are available to consumers.
According to the “Pharmaceutical Bulletin ”, the Ministry of Health issued 44 permits to accelerate the registration of drugs.
Another 80 permits for amendments under the shortened procedure, 11 permits for the circulation of drugs in foreign packaging and 7 permits for the temporary circulation of unregistered medicines in the country.
Earlier, Izvestia reported a deficiency of Tamoxifen, used in many oncological diseases, in particular breast cancer.
In turn, the Ministry of Health reported more than 470 thousand packages of the drug in civil circulation.
That ’ s about six months, they said.
Read also
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The Ministry of Health has issued 44 permits to accelerate drug registration, and 470 thousand packages of Tamoxifen are in civil circulation, with an expected resolution timeline of about six months.

Title:

Content: Advertisement
NEWS
The Ministry of health included iodine, aspirin and paracetamol in the list of potentially deficient drugs
Today at 19: 58
The Interdepartmental Commission of the Ministry of Health included 97 items in the list of drugs that could potentially become scarce in the Russian market.
This is reported by “Kommersant ”.
The list includes iodine, ibuprofen, acetylsalicylic acid (aspirin), lidocaine, paracetamol, fentanyl, phenobarbital (the main component of valocordine and corvalol) and other drugs.
With regard to these drugs, the Government will take measures to ensure that they are available to consumers.
According to the “Pharmaceutical Bulletin ”, the Ministry of Health issued 44 permits to accelerate the registration of drugs.
Another 80 permits for amendments under the shortened procedure, 11 permits for the circulation of drugs in foreign packaging and 7 permits for the temporary circulation of unregistered medicines in the country.
Earlier, Izvestia reported a deficiency of Tamoxifen, used in many oncological diseases, in particular breast cancer.
In turn, the Ministry of Health reported more than 470 thousand packages of the drug in civil circulation.
That ’ s about six months, they said.
Read also
Events of the week on afisha.ru
We recommend you

Other medications in short supply include Paroxetin Actavis 20 mg, Januvia 100 mg tablets, Smoflipid 200 mg/ml 100 ml N10, and Fraxiparine 2850 RÜ anti-Xa/0.3 ml, with expected resolution timelines ranging from January to June.

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Department: there are difficulties with the supply of a number of drugs
The Department of Medicines reported difficulties in supplying a number of drugs, one of which does not have a replacement in the form of another with a similar effect.
The representative of Actavis Group distributor PTC ehf reported on the difficulties with the supply of medication for depression and anxiety Paroxetin Actavis 20 mg, which is expected to last until February.
Other medications with the same active substance and indications are available.
A spokesman for Merck Sharp & Dohme B.V. has reported difficulties with the delivery of the diabetes medicine in the Januvia 100 mg tablets, which is expected to last until February.
Januvia 50 mg tablets are available.
Patients should consult a doctor to continue the course of treatment.
A representative of Fresenius Kabi AB reported on the difficulties with the supply of an infusion emulsion of 100 ml N10 of the drug Smoflipid 200 mg / ml, which is expected to last until the end of January.
The medicine supplies the body with energy and fatty acids.
Available medicine Smoflipid 200 mg / ml in a package of 500 ml N10.
The representative of Mylan Healthcare SIA reported on the difficulties of supplying the solution in the syringe Fraxiparine 2850 RÜ anti-Xa / 0.3 ml and Fraxiparine 7600 RÜ anti-Xa / 0.8 ml, which are expected to last until the end of June 2022.
Other medications with the same active substance and indications are not available.
Fraxiparine is a medicine that helps prevent the formation of blood clots in the vessels and treats already formed blood clots.
Patients should consult a doctor to continue the course of treatment.
The representative of GlaxoSmithKline Trading Services Limited reported on the difficulties with the supply of powder for oral suspension Augmentin Fruit 80 mg / 11.4 mg / ml, which is expected to last until the end of January.
Augmentin Fruit is an antibiotic that destroys infection-causing bacteria.
Augmentin Fruit is available from the distributor First Pharma OÜ.
A representative of GlaxoSmithKline Limited reported difficulties with the supply of Zinnat 500 mg tablets in a package of N14, which is expected to remain until March.
Zinnat is an antibiotic that is used to treat adults and children.
Zinnat 500 mg is available in a N10 package.
The representative of Takeda Pharma AS reported on the difficulties with the supply of spray for the treatment of the common cold Xymelin Menthol 1 mg / ml, which is expected to persist until early February.
A different medication is available with the same active substance and indications.
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Alternative medications are available for some shortages, and patients are advised to consult their doctors for treatment continuation.

In the US, 323 drugs face severe shortages in Q1 2024, including diabetes drugs Ozempic and Mounjaro, chemotherapy drugs, and Amoxicillin for children.

The shortage of Mounjaro is due to unprecedented demand, and Lilly is ramping up production in 2024, while the White House has proposed $3.26-5.11 billion to address shortages.

The FDA needs more power to access drug shortage information, and Congress requires manufacturer transparency on supply chains.

In Taiwan, 22 drug shortages were reported between March 25 and April 4, including Ertapenem Sodium antibiotic, which is expected to withdraw from the market, and Yuanzhou Ginkgo Ning Tablets 40mg, which is in short supply.

Title:

Content: The Ministry of Health and Welfare yesterday announced the establishment of the "Drug Supply Notification Processing Center" and announced the situation of drug shortage for the first time today. According to the Food and Drug Administration, a total of 22 drug shortages were reported between March 25 and April 4, of which 7 were found to have no shortage, 12 were recommended to use alternative drugs, and 1 was launched for no alternative drugs.
However, first-line pharmacists have been slow to respond to the expansion of the drug shortage center, pointing out that there is still a shortage of two to three drugs per day, indicating that the new system has not changed much after the road.
As many as 12 missing drugs are recommended to be replaced by alternatives, including Yuanzhou Ginkgo Ning Tablets 40mg for terminal hemorrhagic disorders, Anxiety Disorder Tablets 30mg, Gastric ulcer Tablets 30mg, Gastrointestinal spasmodic Tablets 10mg, etc.
However, some hospital pharmacists revealed to this newspaper, the Ministry of Health and Welfare "drug supply notification processing center" was established, the immediate impact on the lack of drugs is not large, now there is an average of 2 to 3 drugs per day shortage, yesterday on the road of the lack of drug platform is just another website statistics, "the Food and Drug Administration and its re-statistics of lack of drugs, can be more active, sorting really in the production of medical Agency inquiry? ”
In addition, the back-line antibiotics produced by Merck 1 gram recently also announced that it will withdraw from the Taiwan market, many medical institutions were informed in March that they will no longer supply, due to the fact that no famous drugs are available in China, so that hospitals are worried that they will be available in 1 or 2 months.
Ertapenem Sodium is a common carbapenem antibiotic. Although it is a back-line antibiotic, it is a narrow type of product, so it is usually the first choice of back-line antibiotics. In the future, if manufacturers no longer supply it, hospitals can only use broad-effect antibiotics. Infection control has a negative impact.
Huang Jingtai describes that in the future, if you can't use Yimen treatment, the treatment of bacterial infection will lead to a "bullknife", adding the possibility of future bacterial resistance. Although there are still stocks in the hospital, it is likely to not last this year.
In addition, another antibiotic, Tainin, which is also produced by Merck, has long been withdrawn from the Taiwan market, so infection doctors are worried that they will only be used in the later stage of antibiotics in the future, forming a vicious circle.
Yang Bowen, director of the pharmaceutical division of the Food and Drug Administration, responded that Yimanzhi had notified as early as July last year that due to the decline in foreign production capacity and the increase in the cost of raw materials, the supply of controlled goods was changed, and whether Yimanzhi would withdraw from Taiwan?
Through the internal evaluation of Charmer Shadong, even if the final exit will wait half a year before the market, plus there is a domestic pharmaceutical factory can produce famous drugs, it should not cause too much impact.
# Drugs # Lack of Drugs # Antibiotics # Shortage # Food and Drug Administration

The expected resolution timeline for Ertapenem Sodium shortage is 6 months, and 12 drugs have recommended alternative drugs.

Adderall is in short supply due to FDA limits and manufacturing issues, and the shortage is expected to resolve in April, but alternative ADHD medications are also in short supply.

Title:

Content: PORTLAND, Ore. (KOIN) — Concern is mounting after shortages of Adderall, a prescription medication used by both children and adults with ADHD, have gotten increasingly sparse since the quantities dropped several months ago.

The FDA says the shortage will resolve – but not until sometime in April.

Demand has skyrocketed, and while there are several alternative prescription medications, many of them are also in short supply.

Drug manufacturers say they can’t just make more of the medication because the FDA and the Drug Enforcement Administration limit the active ingredients, amphetamines, which can be abused and cause addiction. Even patients are limited in how much they can get at a time.

OHSU Psychiatrist Dr. James Hancey, who prescribes the medication, said finding the medicine is challenging because patients have to contact their doctor’s office to receive a prescription.

“It’s not one you can just walk around with to shop around for who might have the medication,” Hancey said.

There are some over-the-counter medications that some doctors are recommending as a way to get by, but Dr. Hansey said they are often not strong enough.

The shortage has been especially tough on kids who are prescribed ADHD medication to help them concentrate in school. Parents want to help their children, but are really frustrated.

There’s also concern that teenagers and adults could instead seek what could be deadly counterfeit drugs.

The FDA limits active ingredients due to abuse risk, and patients are limited in how much Adderall they can get, which affects kids with ADHD in school.

Liquid amoxicillin is in short supply due to production delays, and the shortage affects treatment of ear infections and bronchitis.

The FDA lists all short supply drugs on FDA.gov, and production delays and component shortages cause drug shortages.

Ammoncillin antibiotic is in short supply due to high demand, but normal supply is expected to be restored within 2 weeks, and alternative medications are available.

Title:

Content: Recently, pharmacies have responded that the antibiotic "ammoncillin", which is used to treat respiratory diseases, has become vacant, and pharmacies even have to "change drugs" through the Line group.
The Food and Drug Administration said that due to the impact of the unsealing, the demand for antibiotics has also increased, and this year's Spring Festival holiday has 10 days, and manufacturers have stopped work before Ammoncillin is out of stock.
After the Spring Festival, the factory has started work, but the production schedule needs 2 to 3 weeks, and the inventory has been supplied to the medical institutions, and the Food and Drug Administration has requested to reserve a certain proportion to the pharmacy, and strive to restore normal supply within 2 weeks.
Yang Bowen, head of the pharmaceutical division of the Food and Drug Administration, said that with the release of the seal in various countries, the demand for the antibiotic "ammoncillin" used to treat respiratory diseases has also increased.
Ammonicillin is a prescription drug. There are eight licenses in China, and the annual use of Ammonicillin was 48 million in 2019 and 36 million in 2021 during the epidemic.
With the epidemic prevention measures approaching, the Food and Drug Administration has asked manufacturers to increase production at the end of last year, and the monthly supply has increased to 10 million to 12 million capsules between December and January this year.
Recently, pharmacies have popped up empty drugs, and even some pharmacists and clinics have “changed drugs ” through the Line group.
In this regard, Yang Bowen said that this is because this year, there are 10 days of holiday in the Spring Festival, and manufacturers have stopped production.
The drug is a prescription drug, the general public still go to a medical institution to see the medicine, after the Spring Festival, the manufacturers have provided most of the drugs to medical institutions.
Yang Bowen said that the production schedule of drugs takes 2 to 3 weeks, needs to be tested, laboratory, packaging, etc., can not be produced in one week, plus after the holiday, not only respiratory diseases, chronic disease drug demand is also large, the FDA has proposed to manufacturers, ask them to reserve a certain proportion to the pharmacy, strive to restore normal supply within 2 weeks.
Wang Mingyuan, deputy spokesman of the All Federation of Pharmacists Association, said that Ammonicillin is an antibiotic and must be under the supervision of a doctor, and it will only be opened if necessary to remind the public that it must be used.
Although there is an imbalance between supply and demand, there are still other alternatives available, and people do not need to deliberately hoard this medicine.
# Ammonicillin # Food and Drug Administration # Pharmacy # Supply # Pharmacy

In Russia, medicines for Parkinson's disease are in short supply, but drugs for bronchial asthma are now readily available, and thyroid drugs are no longer in short supply.

Title:

Content: MOSCOW, April 11 — PRIME.
Russian Health Minister Mikhail Murashko said in an interview with Naila Asker-zade on the Rossiya 1 channel that there are a sufficient number of medicines in warehouses and medical organizations in Russia.
"There are a sufficient number of medicines in warehouses and in medical organizations," Murashko said.
He noted that stocks of medicines for more than 8 and 12 months in different categories have been formed for preferential categories of citizens.
On a number of drugs signed two- and three-year contracts, said the Minister.
The economic situation in the Russian Federation allows us to look with optimism at the provision of medicines to Russians, said the Minister of Health of Russia.
"Today, everything has stabilized, the economic situation allows us to look at the provision of medicines with optimism," Murashko said in an interview with Naila Asker-zade on the Rossiya 1 channel.
He noted that there were “certain moments ” when wholesalers kept medicines, immediately did not bring them to the pharmacy network.
Murashko noted that for a number of drugs, including for the treatment of Parkinson's disease, while the formation of supply chains is underway, these problems will soon be solved, Russian Health Minister Mikhail Murashko assured.
“For a number of drugs, the supply chain to pharmacies is still being formed, in particular, for Parkinson ’ s disease.
And I think that in a short period of time we will close all this and solve all these problems, ” he said in an interview with Naila Asker-zade on the channel “Russia 1 ”.
It was also noted that there are no longer any problems with thyroid drugs, as well as with the supply and availability of drugs for the treatment of bronchial asthma.
The Minister of Health of Russia also stressed that the domestic pharmaceutical industry faces the task of greater localization and development of drugs, including original ones.
“Today, we set a task for the domestic pharmaceutical industry for greater localization, for the development of drugs, both analogues, generic drugs, and including original drugs, but affecting the same groups of diseases for which imported ones are used, ” he said.
Murashko also recalled that up to 80% of the drugs from the list of vital “with varying degrees ” of localization are domestic.
“In general, the main thing we focus on is the list of vital drugs.
It includes 808 international generic names, these are exactly chemical formulas, and the trade names are much more.
And up to 80% of drugs in one way or another is, ” he said in an interview with Naila Asker-zade on the channel “Russia 1 ”.
The Minister also noted that a set of measures has been taken to “adapt ” drugs that are already in the register, if for example, you need to change the packaging, color or font on it.

80% of vital drugs are domestically produced in Russia, and the localization of the domestic pharmaceutical industry is a priority.

Amoxicillin is in short supply among US drugmakers, including Hikma Pharmaceuticals, Teva Pharmaceuticals, and Novartis' Sandoz business, due to high demand.

Title:

Content: US low on amoxicillin

The infection antibiotic amoxicillin is in short supply among at least three drugmakers, according to the American Society of Health-System Pharmacists and Bloomberg

As of Oct. 20, 14 of London-based Hikma Pharmaceuticals' amoxicillin products and nine of Israel-based Teva Pharmaceuticals' supply are part of the national shortage, according to the ASHP's drug shortage website.

Amoxicillin comes in many forms — including capsules, powders and chewable tablets — but the most common type children take is the liquid form, which makes up at least 19 products that are part of the dearth.

Hikma's oral amoxicillin drugs are on allocation, meaning the drugmaker is curbing new orders to ensure it can meet current contracts. Teva told ASHP it expects its back-ordered products to return to normal supply levels between late October and early December.

Novartis' Sandoz business also has a lack of the antibiotic because of "significant" demand, a company spokesperson told Bloomberg

Hikma, Teva and Sandoz account for three of four top manufacturers of the drug, according to Bloomberg. There are other antibiotics available, but the CDC recommends amoxicillin as a "first-line therapy" for multiple common pediatric infections.

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The liquid amoxicillin form is most affected, with 19 products in shortage, and Hikma is curbing new orders to meet current contracts, while Teva expects back-ordered products to return by late October to early December.

Paxlovid is in short supply, with 180,000 courses available in 2021, but supplies are expected to improve in coming weeks, and Molnupiravir cuts hospitalization risk by about 30%.

Title:

Content: (Bloomberg) -- New treatments for early Covid-19 are now beginning to arrive at pharmacies in New York and elsewhere but remain in short supply, according to a representative of the Infectious Diseases Society of America.

“I know patients who have actually gotten outpatient prescriptions in New York City” of Pfizer Inc.’s Paxlovid, Aaron Glatt, professor and chair of the Department of Medicine at Mount Sinai South Nassau in Oceanside, New York, said Thursday in an interview.

Doctors are anxiously awaiting the new medications as highly transmissible omicron spreads across the U.S. and the world, leading to record case numbers in many regions. While the new variant appears less dangerous overall than earlier strains, the sheer number of cases is threatening health systems.

Paxlovid and Merck & Co.’s molnupiravir have been authorized by the Food and Drug Administration to keep nonhospitalized high-risk patients from needing admission. So far, they work better against omicron than antibody therapies from Regeneron Pharmaceuticals Inc. and Eli Lilly & Co. that were cleared for the same purpose.

Also still in very short supply: sotrovimab, the only monoclonal antibody known to work against the omicron variant. Supplies of the infused drug from GlaxoSmithKline Plc and Vir Biotechnology Inc. are also expected to improve in the coming weeks, Glatt said.

For now, the drugs are only being used in patients at highest risk, because of their scarcity, Glatt said. Pfizer has said that under a federal contract, it expects to have courses of Paxlovid for just 180,000 patients in 2021, but enough for millions next year.

Israel received its first shipment of Paxlovid on Thursday as part of a deal with Pfizer to send about 100,0000 pills. Initial data suggest that it cuts the risk of hospitalization by nearly 90%; molnupiravir also appears effective but much less so, cutting risk of hospitalization or death by about 30%.

The drugs may not be widely available in the U.S. now, but in the coming weeks -- after holiday schedules return to normal -- supplies should improve, Glatt said.

©2021 Bloomberg L.P.

Sotrovimab is in very short supply due to high demand, but supplies are expected to improve in coming weeks, and Paxlovid cuts hospitalization risk by nearly 90%.

Amoxicillin is in short supply, with only 70-80% of the usual supply available, and anticoagulant drugs, anti-allergic drugs, and blood pressure drugs are also in short supply.

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Health Insurance Department: Most of the new list of missing drugs is included in the price range
2023 / 2 / 25 14: 26 (Updated 2 / 25 14: 45)
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Lack of medicine is frequent, recently extended from the community pharmacy to the hospital, the National Health Insurance Department pointed out on the 25th, after comparing the medical profession to introduce a new list of shortage of drugs, most of them are not included in the adjustment.
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(Central News Agency reporter Shen Peiyao, Taipei, 25) The shortage of medicines has been frequently reported, and it has recently been extended from community pharmacies to hospitals.
The Health Insurance Department pointed out today that after comparing the list of new medicines in the medical sector, most of them are not adjusted, and some are machine and freight problems, and supply has been resumed gradually.
According to the "Drug Expenses Target System", the Central Health Insurance Administration of the Ministry of Health and Welfare adjusts the budget of health insurance drugs every year.
Due to the COVID-19 (COVID-19) pandemic, the health insurance drug budget has not been adjusted for two years, and the combined adjustment amount of 110 and 111 is NT $8.18 billion. The original plan was announced yesterday and took effect on April 1, but it was temporarily cancelled.
Health Insurance Commissioner Shi Chongliang yesterday said that the current health insurance contains about 14,000 drugs, the original has been good, is expected to adjust 6009 of them, the remaining 8000 do not adjust, because the medical sector also proposed a number of drugs to obtain difficulties, has brought back the list, but also need a little time to re-examine and calculate, so the announcement was postponed.
Chen Yu-ying, deputy secretary general of the All Federation of Pharmacists Association, said in a telephone interview today that although there is no complete shutdown, the manufacturers will have a slight control on the supply volume, and there is no way to supply the full amount.
Chen Yuying said that in a large hospital, a total of about 34 drugs need to be replaced by other brands, and the supply of the most is only the usual 70 to 80%, including antibiotics "amoxicillin" (Ampicillin), Ampicillin (Ampicillin), etc., as well as anti-allergic drugs, blood pressure drugs, and muscle relaxants for intubation during surgery.
The biggest headache for hospitals is the shortage of anticoagulant drugs.
Chen Yuying said that there are other drugs that can be replaced by oral drugs, but there is only one manufacturer of anticoagulants, one formulation, and another brand will have to be replaced when stocks are exhausted. The mechanism of the drug is not the same, "There is no substitute at all in the clinic, but there is a change in the way."
In response to the shortage of medicines in the hospital, Huang Yu-wen, head of the medical audit and pharmaceutical section of the National Health Insurance Administration, explained that when he communicated with representatives of the medical community on the relevant issues yesterday, the Taiwan Community Hospital Association provided 58 items of shortage drugs, and compared, most of the drugs have not been adjusted in the principle of drug price adjustment.
As for a small number of drugs that are not included in the scope of adjustment, Huang Yu-wen says that most of them are three identical products (the same ingredients, dosage, and content) that have been accepted by Health Insurance for more than 15 years, or have other alternatives for the same indications, and some of the shortage of drugs is due to short-term production problems, such as drug packaging machine failures and shipping delays.
Huang Yuwen said that the initial assessment of medical representatives to put forward a new list of shortage of drugs, does not affect the current price adjustment, will still be announced on March 1. At present, health insurance has received about 14,000 drugs, of which 6009 items, 8.18 billion yuan is expected to be adjusted. (Editor: Li Hengshan) 1120225
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Muscle relaxants for intubation during surgery are in short supply, and 34 drugs need to be replaced by other brands in large hospitals.

The shortage of medicines has extended from community pharmacies to hospitals, and the health insurance drug budget has not been adjusted for two years due to COVID-19.

The Russian market is experiencing a shortage of several medications, including Iodine, Aspirin, Paracetamol, Ibuprofen, Lidocaine, Fentanyl, and Phenobarbital.

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Content: Advertisement
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The Ministry of health included iodine, aspirin and paracetamol in the list of potentially deficient drugs
Today at 19: 58
The Interdepartmental Commission of the Ministry of Health included 97 items in the list of drugs that could potentially become scarce in the Russian market.
This is reported by “Kommersant ”.
The list includes iodine, ibuprofen, acetylsalicylic acid (aspirin), lidocaine, paracetamol, fentanyl, phenobarbital (the main component of valocordine and corvalol) and other drugs.
With regard to these drugs, the Government will take measures to ensure that they are available to consumers.
According to the “Pharmaceutical Bulletin ”, the Ministry of Health issued 44 permits to accelerate the registration of drugs.
Another 80 permits for amendments under the shortened procedure, 11 permits for the circulation of drugs in foreign packaging and 7 permits for the temporary circulation of unregistered medicines in the country.
Earlier, Izvestia reported a deficiency of Tamoxifen, used in many oncological diseases, in particular breast cancer.
In turn, the Ministry of Health reported more than 470 thousand packages of the drug in civil circulation.
That ’ s about six months, they said.
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Russia faces a shortage of about 100 drugs, with 97 drugs on the shortage list, including Immunoglobulin, Paracetamol, and the vaccine for diphtheria, pertussis, and tetanus.

Title:

Content: Links for simplified access
The Ministry of Health of Russia announced the threat of a shortage of about 100 drugs
In Russia, there may be a shortage of about a hundred medicines, - follows from the list of the interdepartmental commission of the Ministry of Health, created to determine the shortage or risk of shortage of drugs in 2022-2023.
The list published in the closed part of the State Register of Medicines drew the attention of the Pharmaceutical Bulletin.
The press service of the Ministry of Health specified that 97 drugs were included in the list.
Their presence in pharmacies is taken under the control of the department.
Among the drugs that may be in short supply are immunoglobulin, retinol, activated carbon, hydrogen peroxide, iodine, paracetamol, a vaccine for the prevention of diphtheria, pertussis and tetanus, and others.
In order to ensure their availability on the market, the agency proposes, among other things, to speed up the registration of a number of drugs, to allow the sale of some drugs in foreign packaging, to issue permits for temporary circulation in Russia of a number of drugs without registration.
After the start of the full-scale war in Ukraine, Russian doctors faced a shortage of more than eighty drugs, including insulin and children ’ s nurofen.
This follows from a survey of the professional community “Vrachi.rf ” .the Ministry of health assures that the supply of medicines to Russia continues, despite the sanctions.
In the European Union, some manufacturers of drugs and components for their manufacture, as well as some firms involved in the supply of medical equipment, say that exports to Russia have been suspended, including due to disruption of supply chains.
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Insulin and Children's Nurofen are also in short supply in Russia, with sanctions affecting medicine exports and disrupting supply chains.

The Ministry of Health in Russia has issued 44 permits to accelerate drug registration, and over 470 thousand packages of Tamoxifen are available.

Title:

Content: Advertisement
NEWS
The Ministry of health included iodine, aspirin and paracetamol in the list of potentially deficient drugs
Today at 19: 58
The Interdepartmental Commission of the Ministry of Health included 97 items in the list of drugs that could potentially become scarce in the Russian market.
This is reported by “Kommersant ”.
The list includes iodine, ibuprofen, acetylsalicylic acid (aspirin), lidocaine, paracetamol, fentanyl, phenobarbital (the main component of valocordine and corvalol) and other drugs.
With regard to these drugs, the Government will take measures to ensure that they are available to consumers.
According to the “Pharmaceutical Bulletin ”, the Ministry of Health issued 44 permits to accelerate the registration of drugs.
Another 80 permits for amendments under the shortened procedure, 11 permits for the circulation of drugs in foreign packaging and 7 permits for the temporary circulation of unregistered medicines in the country.
Earlier, Izvestia reported a deficiency of Tamoxifen, used in many oncological diseases, in particular breast cancer.
In turn, the Ministry of Health reported more than 470 thousand packages of the drug in civil circulation.
That ’ s about six months, they said.
Read also
Events of the week on afisha.ru
We recommend you

In terms of specific medications, Paroxetin Actavis 20 mg is in short supply until February, while Januvia 100 mg tablets and Smoflipid 200 mg/ml 100ml infusion emulsion are in short supply until January and February, respectively.

Fraxiparine 2850 and 7600 RÜ anti-Xa, Augmentin Fruit 80 mg/11.4 mg/ml, and Zinnat 500 mg tablets are also in

Fraxiparine 2850 and 7600 RÜ anti-Xa, Augmentin Fruit 80 mg/11.4 mg/ml, and Zinnat 500 mg tablets are also in