Biohacking, a practice optimizing health and longevity through lifestyle tweaks, is gaining popularity, particularly among women seeking health optimization.

Biohacking aims to improve health and well-being through methods like nutrition, physical activity, and supplements to prolong life.

Popular biohacking methods include intermittent fasting, cold-water therapy, and various supplements.

Intermittent fasting is a key biohacking pillar, complemented by sleep, hydration, exercise, cognitive stimulation, and stress management.

Biohacking carries risks and individuals should approach it with skepticism, critical thinking, and medical consultation.

It is essential to approach biohacking with a nuanced perspective, prioritizing health and well-being over longevity.

Biohacking enthusiasts should consult healthcare professionals before taking supplements or medications due to potential interactions.

High doses of supplements and extreme diets can cause dependency and have unproven long-term effects.

The long-term effects of extreme biohacking methods are uncertain and potentially harmful, causing mental, physical, and emotional exhaustion.

Proper diet, exercise, sleep, and mindfulness techniques are crucial for maintaining physical and mental health and reducing stress.

Certain supplements like metformin and nicotinamide riboside can cause headaches, anxiety, and increased brain cancer risk.

Blood tests and a healthy diet are recommended before considering supplements for longevity.

The long-term effects of extreme biohacking methods, like the 'bulletproof diet' and high-dose supplements, on health are not well understood and may be harmful.

Approach biohacking with a critical perspective, prioritizing evidence-based methods and specialist consultation to avoid harm.

Biohacking can improve health and well-being, but it's crucial to approach it with caution and a nuanced perspective.

Biohacking, a practice optimizing health and longevity through lifestyle tweaks, is gaining popularity, particularly among women seeking health optimization.

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Biohacking & Toxic Masculinity: How Women Dismantled The Boys Club

Author: Medical reviewer:
Beauty & Health Editor
By Jamie Schneider
Beauty & Health Editor
Jamie Schneider is the Beauty Editor at mindbodygreen. She has a B.A. in Organizational Studies and English from the University of Michigan, and her work has appeared in Coveteur, The Chill Times, and Wyld Skincare.
Medical review by
Bindiya Gandhi, M.D.
Physician
Dr. Bindiya Gandhi is an American Board Family Medicine–certified physician who completed her family medicine training at Georgia Regents University/Medical College of Georgia.
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Take a quick search for “biohacker” on TikTok (a tag with over 137 million views), and you’ll discover a slew of men discussing their muscle gains, testosterone levels, and cold plunge routines. You’ll see some women on the page, but the space is undoubtedly dominated by male energy. And think of the outspoken biohackers you may listen to on podcasts—chances are most of them are men, too.

This gendered approach to biohacking, while pervasive, is simply misguided. But now, women are asserting their authority in health optimization, and we expect their emphasis to soar in the year ahead.

Meet the experts

Molly Maloof. M.D.

Molly Maloof. M.D. provides health optimization and personalized medicine to high-achieving entrepreneurs, investors, and technology executives. Since 2012, she has worked as an advisor or consultant to more than 50 companies in the digital health, consumer health, and biotechnology industries. Her company, Adamo Bioscience, is working on sexual health optimization.

Gabrielle Lyon, D.O.

Gabrielle Lyon, D.O. is a board-certified family physician leading a disruption in modern medicine that focuses on the largest organ in the body: skeletal muscle. With a background that includes a combined research and clinical fellowship in geriatrics and nutritional sciences at Washington University and undergraduate training in nutritional sciences at the University of Illinois, she is a subject-matter expert on protein for health, performance, aging, and disease prevention.

Stacy Salvi

Stacy Salvi is the vice president of product and strategy at the medical device company Movano Health—the creator of the Evie Ring, the first medical-grade health wearable designed for women.

Mona Vand, PharmD

Mona Vand, PharmD studied pharmacy at Massachusetts College of Pharmacy and Health Sciences before developing her platform that shares holistic wellness advice.

Why biohacking isn’t just for “bros”

“Women are the original biohackers,” declares family physician, Molly Maloof, M.D. “Our hormones change throughout our lives, and this requires us to adapt accordingly.” Our biology means that women often need to constantly edit their health routines and experiment with lifestyle habits as time goes on. Isn’t that the very definition of biohacking?

Let's back up: Here at mindbodygreen, we think of “biohacking” as the practice of making lifestyle tweaks to optimize health and promote longevity. Not shortcuts—contrary to popular belief—but low-lift, everyday habits that complement and enhance an existing well-being routine. Think: optimizing your exercise regimen using tools and techniques (the “biohacks”) to enhance muscle growth. It’s essentially all about advancing health with “do it yourself” biology—a topic that can pique anyone’s interest, regardless of gender.

“[Women] have a most complex physiological lifecycle that requires us to track and manage fertility, pregnancy, breastfeeding, sexuality, perimenopause, and menopause. So we should be looking at biohacking as a path to even greater health and owning the opportunity to improve our lives,” says Maloof.

Yet many women feel intimidated to enter the biohacking scene as it exists today, turned off by the male-dominated energy in the room.

Women are the original biohackers

Molly Maloof, M.D

“Biohacking has always grabbed my attention, and I want to learn, but it sometimes makes me really stressed out, because I go into this state of perfectionism where I have to do all the things,” says doctor of pharmacy and wellness practitioner Mona Vand, PharmD. “The few biohackers that I followed were all males… it just doesn't really resonate with my energy.”

This male energy is not only frustrating but can potentially harm women’s health in the long run. After all, building muscle, prioritizing protein, and keeping an eye on various health metrics are crucial for longevity—in some cases, these proactive measures can save lives. When women don’t get involved, it can totally impact their well-being.

“Physical strength is nonnegotiable,” says functional medicine doctor Gabrielle Lyon, D.O. “I've been a physician since 2006, and I've never heard someone say, ‘I regret being physically strong.’” And the muscle-building space impacts more than just physiological changes, she says. “You optimize fertility, you make healthier babies, you help the epigenetics of your child,” Lyon adds. “You age better, your skin is better, you're less likely to fall and break a hip… There's nothing that doesn't get better the stronger you are.”

So let’s be clear: Dismantling the biohacking boy’s club is not just about helping women feel included; there are real health implications at stake here.

Why the biohacker space actually really needs a dose of feminine energy

I’d be remiss not to mention how biohacking culture can easily become synonymous with hustle culture (some experts don’t even like to use the term, as it implies you can achieve optimal health with quick fixes). But as more women enter the biohacking space, we expect it to become more intuitive and less about hitting every single benchmark. From there, we predict women will focus more on sustainable changes long-term instead of a gazillion quick hacks.

“I used to think it was a flex to do a million things at the same time and habit stack,” Vand recounts. “I now carve out time for doing things that have no efficiency to them, that are strictly for joy or rest and relaxation, versus benefiting my longevity or health. It can be a little bit obsessive when you get into this thought pattern, and I just don't resonate with it.”

This doesn’t mean biohacking will become “softer” as it embraces feminine energy. But there’s an opportunity here for women to introduce some much-needed flexibility into a space that has long felt needlessly rigid.

How the biohacker game is changing — and where it’s headed next

Thanks to a growing awareness that healthcare protocols should not be gendered, more women are now starting to pay attention to markers of performance like lean muscle, hormetic stressors, VO2 max, HRV, zone 2 training, etc. “Cold plunging, saunas, and harder, more physical activities are not just for the boys anymore,” adds Lyon—and we expect an even bigger shift to come in 2024.

“I think it’s super exciting to see biohacking become more mainstream and more women joining the conversation,” adds Maloof. She praises apps like Wild.AI, for women who aim to make lifestyle adjustments based on their menstrual cycle, and Zero, for women who want to dabble in time-restricted eating, both of which have helped to herald the shift.

Other existing health optimization companies are now inviting women into the conversation by introducing specific features informed by their unique physiology. WHOOP, for example, is currently working on upgrades to their popular health-tracking band: “We did a study recently where we learned a lot about how a woman's body changes during pregnancy and how her heart rate variability (HRV) will evolve. It'll decrease, and then about seven weeks before she gives birth, it will increase sharply,” explains Will Ahmed, WHOOP founder and CEO, on the mindbodygreen podcast

If a woman didn’t know that this was supposed to happen, she might look at this stark increase with a critical (or anxious) eye. “We've been able to take population-level data on pregnant women and now have a feature in the app, where a woman can see how her body is evolving alongside what other pregnant women are experiencing,” he adds.

Similarly, creatine supplements—from the ingredients to the packaging—are no longer marketed toward dudes looking to bulk up, and we are certainly here for it. After all, muscle mass is a predictor of longevity and healthspan, so supplements that promote it can help all of us “hack” our health in a big way.

And as Lyon notes, women have lower endogenous creatine stores compared to men (meaning, they have less available). And the amino acid has been associated with significantly increased muscle mass1 in both men and women, without increasing the risk of adverse outcomes2, like weight gain. “Most of the women in my practice will go on creatine, and they find anecdotally that it really improves both anaerobic and aerobic exercise performance,” Lyon shares.

Not to mention the supplement’s brain health perks: Taking creatine has been shown to benefit both working memory and processing speed3 as well as cognitive longevity4. “It is above and beyond simply sport performance,” adds Lyon, who has certainly seen an uptick in women curious about creatine.

As women feel intimidated (or even restricted) by biohacking spaces, some experts have taken it upon themselves to create new ones that center the feminine. For example, neuropsychophysiologist Kayla Osterhoff, MPH, offers a Women's Biohacking Mini Course, consisting of lifestyle routines and tips aligned with female physiology.

Osterhoff also recently presented at the 2023 Dragonfly Live Conference—among other female biohackers—to discuss the latest advancements in women's well-being and the “health revolution” that’s sweeping the mainstream. This conference aims to gather the “who's-who” in the health space to discuss cutting-edge strategies and innovations that optimize well-being—by having women biohackers at the forefront of the conversation, we can expect them to hit the main stage in a broader sense.

Or take the brand new Evie Ring, the first medical-grade health wearable designed for women, created by medical device company Movano Health. The technology ties hormonal information to a woman’s sleep, activity, and heart health data (among other metrics).

For instance, “If we notice a more restless night of sleep in the luteal phase, we'll point it out and also give some strategies for how somebody may attack their day, despite having not gotten as good of a night of sleep,” says Stacy Salvi, vice president of product and strategy at Movano Health. Similarly, “We know that there are cardiovascular implications when your estrogen drops, so they would want to keep a better look on the function of their heart,” she adds. “This would be something that they would be able to do from our app.”

Even the design itself was made with women in mind: The ring features an open band meant to accommodate how women’s fingers change in size throughout the day, so it can stay comfortable.

To avoid needless stress, Evie also limits the amount of goals you can set on the app. “You can only set three at a time, because we do not want to overwhelm [users] with a bunch of different things,” says Salvi. “I mean, I'm an overachiever. I probably would set every single goal and then fail at them.” And heaven knows we don’t need yet another way for busy, overwhelmed women to feel like they’re failing in a society with unsurmountable standards.

Forecasting the future

A woman walks up to the weight rack in 2024. She sees the usual suspects—bros pounding protein shakes and grunting through their bicep curls—but now she also sees a fair amount of women on the scene. They’ve got creatine supplements! Fitness trackers! Kettlebells! (And no, they aren’t pink.)

Granted, we still have a ways to go before women feel totally embraced by the biohacking space (we’d first have to close the centuries-long gender gap in science and medicine), but it’s clear that the arena is becoming way less of a boy’s club. “And the world is ready, my friend,” says Lyon. “The world is absolutely ready for this.”

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Biohacking aims to improve health and well-being through methods like nutrition, physical activity, and supplements to prolong life.

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Content: Home » biohacking, reprogramming mind and body to live better

biohacking, reprogramming mind and body to live better

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It’s called “biohacking” and it comes from Silicon Valley. Listen: The long life diet: the longevity formula is calorie restriction …

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It’s called “biohacking” and comes from Silicon Valley.

A relatively new word that comes from the union of “biology” and “hacker” and indicates the attempt to positively influence the functioning of the organism, by hacking, ie trying to “force”, one’s genetic heritage. A strategy to live better and longer launched years ago by Californian top managers and which then spread throughout the world. How to upgrade the “operating system” of the human body? No manipulation, here we are talking about “reprogramming” and new lifestyles. “Our genetic heritage has enormous unexpressed potential that can be activated,” he explains Fabio Piccinidoctor and psychoanalyst, researcher of Food Sciences of theMarche Polytechnic University, author of the book “Biohacking Techniques: how to optimize metabolism to increase health and longevity”. “Biohacking aims to activate epigenetic modifications by awakening dormant genes to enhance the body’s resources.” While genetics studies the structure of DNA, epigenetics the way genes express themselves, i.e. how much they are turned on or off. “We’re talking about a set of strategies that aim to strengthen the body from a physical and mental point of view, first of all through nutrition, sleep quality, physical activity, cognitive stimulation”. One of the pillars of biohacking and the intermittent fasting, Piccini adds, which plans to concentrate the diet in a precise time span of the day (to be followed always under medical supervision). «But it is equally important to take care of sleep, we know very well that sleep debt accelerates aging and that 30-40 percent of people sleep too little. Just as it is essential to check thehydration. Physical training must also be intermittent, with recovery periods in place to allow the muscle layers to rebuild. And then, you have to keep learning something at any age, another pillar of biohacking: studying music or a new language, for example, to counteract cognitive degeneration”.

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THE QUALITY OF LIFE

Sandra Milo is one of the supporters of this well-being and longevity strategy. «I’m lucky, at 90 I’m in full health and I still have a great desire to enjoy life. I don’t know if it’s a matter of genetics, nor do I think there is a “magic formula” of longevity, but I have certainly always been careful to lead a healthy life. There is nothing more beautiful than reaching old age with a smile and in full autonomy », says the actress who baptized the first Biohacking Suite in Rome. “Our mission is not so much to lengthen life but to improve its quality by lowering the rate of morbidity,” explains Dr. Claudio Urbani, specialist in regenerative medicine, neuroscience and stress therapy, head of the longevity center Umb. «Biohacking aims to modify dormant functional responses from non-use, from muscular or cardiovascular function to flexibility. It is about regaining possession of the body and the mind-body axis, starting with stress management». Diagnosing your own state of “aging” involves a series of tests. «The measurement of oxidative stress which measures the quantity of free radicals and indicates any inflammatory states, plethysmography to evaluate the functionality of the microcirculation of the legs, impedancemetry to study body composition, fat and lean mass, nutritional status and hydration level. And only after the check is a tailor-made program created for each person. Among the suggested therapies, there is also that of the cold which stimulates the metabolism and reduces inflammation ».

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Popular biohacking methods include intermittent fasting, cold-water therapy, and various supplements.

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Content: TV legend Davinia Taylor has revealed how well she is feeling after undertaking a new lifestyle that involves biohacking.

Biohacking occurs when someone changes their nutrition and lifestyle in order to make themselves healthier. Each person who biohacks does so in a different way whether it’s cutting out alcohol, taking supplements, or engaging in anti-ageing procedures.

Davinia – who starred in Hollyoaks – has explained that her biohacking involves cold-water therapy and removing inflammatory foods from her diet.

As a result of her new lifestyle, which also includes the use of saunas and supplements, Davinia has said that she now feels healthier than she ever has before.

Speaking to Hello! Davinia said that she entered a difficult period of poor mental health after the death of her mother when she was 35.

She added: “Boredom drove me to drink and then to eat unhealthily. I don’t want to go into my 50s feeling bored, so I had to find another way to get the dopamine I crave.”

On the techniques she uses for her biohacking, Davinia reveals that one of her routine acts is taking supplements from a company she founded. Known as WillPowders which contain collagen, protein, bone broth, and MCT (a healthy form of saturated fat) they have become an essential part of her routine.

Davinia explained: “If I don’t have my morning keto creamer and collagen, I’m going to end up binging on croissants or brownies. It’s how I’m wired after my 1980s upbringing.”

This isn’t the first time Davinia has spoken about biohacking. Earlier this year she told the Evening Standard that it wasn’t a case of taking big measures to improve one’s health.

She said: “There's so much doom and gloom… There's so much doom and gloom…There are so many little hacks you can do just to make yourself feel mentally better.”

Davinia highlighted the benefits of cold-water therapy, a method she said can be cheap to access: “The water’s freezing in this country two-thirds of the time. And on the few months a year when it’s not, just go to the supermarket, buy some ice bags and empty them into the bath.”

Intermittent fasting is a key biohacking pillar, complemented by sleep, hydration, exercise, cognitive stimulation, and stress management.

Biohacking carries risks and individuals should approach it with skepticism, critical thinking, and medical consultation.

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Content: Support Your Freedom to Speak:
A Community of Biohackers & Transhumanists "Ending the Blight..." ☠ with Justin of LongeCity.org
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Published Yesterday

My interview with Justin Loew of The Immortality Institute aka Longecity forum, the most popular online community of Biohackers and Transhumanists. Their ambitious mission is to end the blight of involuntary death.

1:50 More than just a forum

3:58 The mission

10:80 How does Longecity support anti-aging research

13:05 How can people contribute to anti-aging science

17:50 Are there any research projects specific to supplements?

20:22 What I love about Longecity

25:00 Human rejuvenation

26:16 "Smart drugs are the gateway drug to anti-aging"

27:10 Justin's interest in anti-aging

30:20 Evangelizing longevity (and Transhumanism?)

34:20 Risk-averse biohacking

43:10 What do you do for personal development?

44:50 Is virtual reality an addictive trap? Meta?

47:16 Popular threads - Is it possible to eradicate fear? Visiting Chernobyl?

About Longecity 📑 Everything mentioned here

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Invest at least $150 in your Biohacking and get a helpful 30-minute free Biohacking consulting call with me. See my recommended Nootropics sources and Biohacking products here:

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I'm not a doctor, medical professional, or trained therapist. I'm a researcher and pragmatic biohacking practitioner exercising free speech to share evidence as I find it. I make no claims. Please practice skepticism and rational critical thinking. You should consult a professional about any serious decisions that you might make about your health. Affiliate links here support Limitless Mindset.

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It is essential to approach biohacking with a nuanced perspective, prioritizing health and well-being over longevity.

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Content: 18 +
• Health
• Health
Health care
Naive biohacking: why is it dangerous to take vitamins “just in case ” and is it true that hacking the body is the way to nowhere (and not to eternal life)
To live longer (for herself and her family), to avoid cancer and heart disease, biohacking enthusiast (now in the past!) and lifestyle podcaster Teresa Skrobanek conducted an experiment and plunged into the world of a thousand and one supplements for longevity.
Whose infectious example was she inspired by?
What was the danger of taking her medicine for diabetes and vitamin B capsules (it is recommended for everyone to calm down!)?
After what biohacking did Teresa really feel better?
Let ’ s share her story.
Master1305
Biohacking experiment
At the end of 2022, Teresa Skrobanek, a responsible mother and grandmother, decided to try to include “longevity ” supplements in her diet.
The general goal is to live as long as possible (for yourself and your family) and avoid breast cancer and heart disease, the risk of which is higher in women over fifty (and Teresa was 57 at the time).
Anti-age drugs were prescribed by a doctor, but, apparently, the specialist was free to relate to the ratio of anamnesis and goals of taking drugs.
In April 2023, Teresa discovered that the capsules in her medicine cabinet were metformin, which is usually prescribed to patients with type II diabetes.
Although the woman did not suffer from this disease, the doctor prescribed the drug due to the fact that the results of the studies were encouraging (but not guaranteed!) - it helps to fight aging
Teresa has also tried over-the-counter drugs, such as nicotinamide mononucleotide (NMN) supplements, which supposedly, but not proven, speed up metabolism and reduce signs of growing up.
According to the experimentalist, she followed the example of the brightest biohacker – IT billionaire Brian Johnson, who takes about two dozen supplements a day, uses at least 7 skin creams and annually spends $2 million on unusual procedures to restore youth (for example, bowel photos, blood transfusions, weekly acid peels and laser therapy).
20 supplements a day and no rejuvenation
The more and longer Teresa took the drugs, the more she doubted.
Feeling worse, and Skrobanek plunged headlong into the study of dietary supplements - the results were contradictory.
For example, studies have shown that the widely advertised low-age supplements of nicotinamide riboside (a form of vitamin B3) increase the risk of brain cancer.
And the unpleasant consequences of the use of metformin (remember, Teresa took the medicine for diabetes, not being a diabetic!) were headaches, drowsiness and anxiety.
“I started to have a headache.
I felt very tired, although the pills were supposed to give me strength, ” Skrobanek told The New York Post, with whom she shared her entire story.
How do I know that taking these substances will not harm my kidneys or liver and will not cause cancer in 5-10 years? ”
beast01
Errors made by Teresa, which can not be made by biohackers novice
At TikTok, where the hashtag # BioHacking has garnered more than half a billion views, proponents of the biohacking movement boast of swallowing 70 to 150 different rejuvenating dietary supplements every day.
For example, to slow down the aging process, businessman Joe Cohen takes rapamycin, an FDA-approved drug that a 2014 study found could help increase life expectancy.
However, Cohen told The Post that he does not recommend a strict regime to his followers: mindlessly copying from and to the anti-age program of trendsetters is dangerous!
Instead, an experienced biohacker (Joe says he ’ s been studying this phenomenon for 20 years!) encourages newcomers to take blood tests first to determine the body ’ s biological needs and deficiencies, carefully examine the benefits and side effects of any supplements, and take only what seems right.
Cohen clarifies: “By understanding your physiology, you can take certain medications that will boost your energy, mood, and chances of avoiding age-related illnesses.
Preserving health is much more important than simply prolonging existence. ”
According to the businessman, his goal is to live as long and healthy a life as possible (and not necessarily up to 150 years)!
Roman Samborskyi
If not biohacking, then what (spoiler: food)
New York City Nutrition nutritionist Diana Rodriguez agrees with Cohen.
But to start your way to longevity offers still not with tablets, but with a healthy diet: “It is recommended to use food as the first method of preventing dangerous diseases.
Fruits, vegetables, low-fat proteins, nuts and legumes, in which "tons" of vitamins and minerals, can be very useful. "
Increasing nutrient intake through organic whole foods is something Teresa Scrobanek started doing in June 2023, when she gave up the supplement diet once and for all.
And she never felt better:
“If a long life meant that I got it with terrible side effects due to taking supplements, then I would prefer a shorter, but better life, which is based on proper nutrition and training, ” concluded Teresa.
The editors remind that drugs, vitamins, dietary supplements and food products have contraindications.
A specialist consultation is required.
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Biohacking enthusiasts should consult healthcare professionals before taking supplements or medications due to potential interactions.

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Content: Skip to content

Dangers Lurking in Your Medicine

Just because it’s prescribed, doesn’t mean it’s safe.
FACT CHECKED BY Emilia Paluszek

Are you aware of potential dangers linked to your prescription and over-the-counter medications? "Every person has a unique set of circumstances, a unique set of disease states, is taking different drugs, and reacts to medications in a unique way. You can't say that just because a drug that is safe for someone else, it will be safe for you," says William Churchill, chief of pharmacy services at Harvard-affiliated Brigham and Women's Hospital. Here are five dangers connected to common medications, according to experts. Read on—and to ensure your health and the health of others, don't miss these Sure Signs You've Already Had COVID.

1

Mouthwash

Alcohol-based mouthwash can pose serious risks to your health, experts say. "Think of mouthwash as the equivalent of unnecessary antibiotics in your mouth," says Mark Burhenne, DDS. "In the same way that antibiotics totally disrupt the balance of bacteria in your gut (which can lead to poor immune function and a host of other problems), mouthwash destroys all bacteria indiscriminately. And just like you need them for gut health, you need good bacteria to support your oral microbiome, which can decrease the risk for common issues like cavities, gingivitis, and bad breath."

2

Prescription Opioids

"What makes opioid medications effective for treating pain can also make them dangerous," says Carrie Krieger, PharmD. "At lower doses, opioids may make you feel sleepy, but higher doses can slow your breathing and heart rate, which can lead to death. And the feelings of pleasure that result from taking an opioid can make you want to continue experiencing those feelings, which may lead to addiction. You can reduce your risk of dangerous side effects by following your doctor's instructions carefully and taking your medication exactly as prescribed. Make sure your doctor knows all of the other medications and supplements you're taking."

3

Grapefruit

Grapefruit can interfere with prescription medications, experts warn. "Grapefruit and certain other citrus fruits, such as Seville oranges, can interfere with several kinds of prescription medications," says Katherine Zeratsky, RD, LD. "Don't take these interactions lightly. Some can cause potentially dangerous health problems. If you take prescription medication, ask your doctor or pharmacist whether your medication interacts with grapefruit or other citrus products. Problems arise because chemicals in the fruit can interfere with the enzymes that break down (metabolize) the medication in your digestive system. As a result, the medication may stay in your body for too short or too long a time. A medication that's broken down too quickly won't have time to work. On the other hand, a medication that stays in the body too long may build up to potentially dangerous levels."

4

Beware of New Ingredients

With so many new supplements containing new, untested ingredients, it can be incredibly difficult to gauge how safe—or dangerous—they might be. "The problem that we've had recently, in recent years especially, is that there's been an explosion of new ingredients," says Pieter Cohen, MD, an internist at Cambridge Health Alliance and associate professor of medicine at Harvard Medical School. "So, it's not only that we're worried about the ingredients that are legal and permitted in supplements or historically used in supplements for many years, but that there are many of these ingredients—these are individual compounds found in botanicals or other substances—that can pose health risks. Nowadays we're seeing so many new innovations or brand-new ingredients being introduced to supplements. Again, because the FDA isn't vetting these products before they show up on store shelves or on the internet, what happens is that they can pose unpredictable risks."

5

OTC Painkillers

People taking over the counter pain medication should be careful to follow dosage instructions and keep track of the time painkillers are taken to avoid accidental overdose. Over the counter medication is real medication—and can have serious side effects. "OTCs can increase blood pressure, pose cardiac risk, worsen asthma and complicate infections," says pharmacist Dean Mercer.

Ferozan Mast
Ferozan Mast is a science, health and wellness writer with a passion for making science and research-backed information accessible to a general audience. Read more about Ferozan
Filed Under

High doses of supplements and extreme diets can cause dependency and have unproven long-term effects.

Title:

Content: A tech millionaire who lives on a bizarre diet of mushy peas and pills hopes to severely limit his ageing process and become 18 years old again.

Bryan Johnson, who has taken 33,000 images of the inside of his bowels, claims to have the fitness of an 18-year-old due to chowing down on 80 vitamins and minerals a day.

His 'Project Blueprint' sees him spend around $2million every year on a mad diet and specialists that monitor his vital organs.

Last month, his 17-year-old son Talmage donated his blood to his dad, who in turn gave blood plasma to his father Richard, 70.

The idea behind the voluntary treatment came because older rats showed signs of becoming livelier when infused with the blood of younger rats during experiments.

"We have perfected blood-drawing," he told the MailOnline. "Yes, it hurts. What I am doing can be incredibly painful. But I believe it will be worth it in the end."

The 45-year-old eats around 70lbs of pureed vegetables a month and his strict routine sees him go to bed at 8.30pm every single night.

Johnson, who sold his Braintree Venmo business to PayPal for $800million, eats exactly 1,977 calories every day.

"I currently have no plans to die,' he said also claiming his diet of almond milk, walnuts, flaxseed and berries means he has the heart of a 37-year-old and the completion of a 28-year-old.

The new lifestyle is a big change for Bryan, who became overweight and unhappy after he sold his business and went through a tricky divorce.

He added that there was an "Evening Bryan" who would make him eat fatty foods with that proviso he worked out a day later.

Inevitably, Evening Bryan was telling lies.

He added: "It took me years to remove that internal demon. I learned how to recognise him and I would say, 'Thank you Evening Bryan, but it's not going to happen. We know what happens when we eat too much and we don't feel good… so no."

Normal, everyday Bryan now argues that humans are "mad" as a species because we choose to have items like cigarettes, alcohol and junk food.

His lifestyle changes don't just stop at his diet, blood and exercise, Bryan wears special glasses to block out blue light and wears a device that monitors nighttime erections.

A small dose of testosterone is needed to redress the balance his restrictive balance causes and a dose of lithium also helps his mood.

He now hopes to extend Project Blueprint to a woman and Bryan said he has narrowed down the applicants from "thousands of women".

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The long-term effects of extreme biohacking methods are uncertain and potentially harmful, causing mental, physical, and emotional exhaustion.

Title:

Content: I Was Experiencing Extreme Burnout Until I Practiced These 3 Things to Come Out Stronger

Learn how to fight mental burnout and become a better entrepreneur with these three simple practices that most already know but often forget about.

By Ron Lieback

Opinions expressed by Entrepreneur contributors are their own.

Mental burnout, unfortunately, compliments entrepreneurism. There's no denying this sentiment, but I've discovered three proven practices that continuously help bypass much of that mental exhaustion.

The practices — rooted in physical health maintenance, meditation practices and mandatory downtime — take minimum effort or time. These insights will help keep you energized in your entrepreneurial journey without burning out — something I experienced multiple times throughout my ongoing entrepreneurial journey and promised myself that burning out would never happen again.

Related: 3 Insights From the First Large-Scale Study on Burnout and Entrepreneurs

Identifying and checking for mental burnout

According to the nonprofit HelpGuide.org, mental burnout is a state of physical, emotional and mental exhaustion caused by prolonged stress. I've recognized the following multiple times while leading my agency and productivity consulting practice:

  • Feeling overwhelmed or emotionally drained
  • Lack of motivation
  • Irritability
  • Insomnia or excessive sleep
  • Loss of interest in once enjoyable activities
  • Decreased productivity at work or school
  • Increased anxiety or depression

These factors can quickly creep in without you noticing it. Author and lecturer Chris Bailey helps us better understand this. In his latest release, How to Calm Your Mind, the productivity hacker says understanding and being aware of the six burnout factors within our work life can help us overcome it.

The six factors are:

  • Workload (How demanding the workload is)
  • Lack of control (How much autonomy, resources and freedom over workload)
  • Insufficient rewards (Financial, social or intrinsic)
  • Community (Quality of work relationships and interactions)
  • Fairness (Treated respectfully)
  • Values (Does the work have a sense of purpose aligned with values?)

Bailey says to set reoccurring calendar events to check in on yourself to create awareness around the six factors. He says he checks every six months; I have bi-monthly calendar alerts set now to check on these six factors. It's shocking how much they pop up, although I'm aware of them.

With that said, it's essential to recognize when you are starting to feel burned out so that you can take steps to prevent it from getting worse. Mental burnout can be difficult to identify, but recognizing the signs early on is key in developing strategies for battling it.

For new entrepreneurs, the following tactics can be eye-opening, regardless of how simple each sound. And for seasoned entrepreneurs, it's always good to get back to these basics. For example, I recently acquired an entrepreneurial assessment software company and quickly lost myself, forgetting many of these basics.

Related: An Entrepreneur's Greatest Asset Is Wellness. Here Are 5 Ways to Protect Yours.

1. Prioritize energy

Although many slog through work and become successful, the efforts take more time and longer-term health suffers. This leads to mental burnout. Focus on creating sustainable energy through proper diet, exercise and sleep, and you'll be able to focus not only sharper but also longer.

After nearly two decades of biohacking and testing various diets, I mostly follow Dr. Gundry's diet laid out in Breaking the Keto Code. Still, I tend to rely on more supplements and longer periods of fasting. Exercises include only two strength-training resistance workouts weekly, along with much walking/hiking, stationary biking, off-road motorcycling and bouncing daily on a mini trampoline in my office.

As for sleep, I learned to regulate my sleeping patterns and use Circadian Optics lighting every morning when I wake up to start the day off through reading, writing or meditating. I hack my sleep in various ways, but my favorite includes a proper cocktail of magnesium, zinc, potassium, GABA, ashwagandha and Kava, along with no food or alcohol at least three hours before snooze time. So test, tune and find what works for you.

2. Practice meditation and mindfulness daily

Although the benefits are proven, and it's well-known across the world of entrepreneurism, many still don't meditate. It's a mindset that one must discover, and once discovered, the benefits of relaxed and focused thinking help you produce more quality work in less time.

I treat meditation like brushing my teeth; it's just part of life now. It helps clear the mind and provides some insight into any problems causing stress. I'm a huge fan of Vishen Lakhiani's 6-Phase Meditation Method, which works wonders in roughly 20 minutes per day and doesn't require traditional methods like sitting in the lotus position or clearing the mind of any thought. Want to make it even more rewarding? Compliment the meditation with a FAR Infrared sauna blanket. I typically do the 20-minute 6-Phase, followed by another 20 minutes of the sauna while listening to theta or delta wave sounds.

Meditation and mindfulness techniques can clear your mind from negative thoughts and allow you to focus on the present moment instead of worrying about what's ahead or what's happened in the past. The outcome is less stress and a fresh look at everything. Others are 5 a.m. Club workoutaholics, but I have more energy and focus on meditation.

This will help relieve stress levels significantly and enable you to approach work with more clarity and purposeful action steps.

Related: How Mindfulness Can Take Your Entrepreneurship to the Next Level

3. Enforce downtime for mental relaxation and productivity

Scheduling regular breaks throughout the day allows for some time away from work, giving your brain a chance to relax before returning to full focus. My threshold for deep, focused work is about 1.5 hours straight; then I can feel my mind slowing. That's when I take a break for an analog activity, sometimes a mere 10 minutes of reading something drastically different from what I'm working on or challenging myself for 20 minutes with jazz guitar lessons.

Working nonstop without any breaks will eventually lead to feeling overwhelmed with everything that needs to be done within a certain period. On my deepest workdays, such as writing or creating client strategies, I break for an hour, typically around noon, to take a bath. This supercharges like no other.

My office is a rented lake house, which makes day baths simple. If you work in a traditional office building, try working from home on the days you need the most focus and spend some time soaking. All my greatest client strategies and business/investment ideas manifested while soaking.

It is vital not only to take short breaks daily, but also to schedule mandatory downtime away from work. For example, I totally shut off every Wednesday after 5 p.m. and one entire day on the weekend. That means zero emails, computers, answering calls or anything related. This helps avoid burnout.

Mental burnout can be a difficult obstacle to overcome, but with the optimal tactics, such as the simple ones above, you can learn how to battle it. By taking time for sustaining energy through physical health, meditation and mandatory downtime, You can become a better you and have time to focus not just on the day-to-day work duties but on ideas that will change the world — a mission that should be the sharpest focus for every entrepreneur.

Ron Lieback

Entrepreneur Leadership Network Contributor

ContentMender Founder, Author

Ron Lieback is the founder and CEO of ContentMender, an SEO-driven content marketing agency, and a productivity hacker. He is also the author of 365 to Vision: Modern Writer's Guide (How to Produce More Quality Writing in Less Time).

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What are the risks and dangers of combining the keto diet and intermittent fasting?

Proper diet, exercise, sleep, and mindfulness techniques are crucial for maintaining physical and mental health and reducing stress.

Certain supplements like metformin and nicotinamide riboside can cause headaches, anxiety, and increased brain cancer risk.

What are the risks and dangers of taking frequent nutritional supplements without a doctor's supervision?

Blood tests and a healthy diet are recommended before considering supplements for longevity.

The long-term effects of extreme biohacking methods, like the 'bulletproof diet' and high-dose supplements, on health are not well understood and may be harmful.

Title:

Content: New superhuman brains.
About drugs that make you smarter and more miserable!
Entrepreneur and programmer Dave Asbury ’ s mornings may not seem different at first glance than anyone else ’ s.
Dave wakes up and takes his young children to school, then comes home and makes himself a breakfast of coffee and butter.
Then, he walks into his office, reaches out to a corner, pulls several capsules out of boxes that look like medicine, and then starts working.
[1] Here it is.
Everything is normal, until we discover that the capsules he takes are not really drugs, but drugs.
Dave ’ s use of these drugs cannot be considered strange: throughout human history, before civilizations even existed, drugs accompanied humans.
For the damage that may lead the individual to death, some found in them an escape from the worries and burdens of life, although the price they will pay for this is high.
What is really strange is that what Dave, and many others, want from taking a certain type of drug is the complete opposite of all this; he doesn ’ t want to get away with it every morning; he wants to indulge more in it and manipulate it to his advantage; he wants to become smarter, more productive, richer.
Dave ’ s drugs are neither weed nor opioid, nor are they similar to any other familiar drug, Dave taking nootropics, or “smart ” drugs.
The chemist C.C. didn't have a clue.
Giragia Yuma said that the word he invented as the name for the drug Pristam, which he installed in his laboratory one day in 1964, would become so popular 60 years later.
The name of this compound came from the combination of the Greek words "nos", which means brain, and "tropin", which means "me," and created in his laboratory the first drug that he hopes will succeed in bending the brain of those who use it.
[2] Like any medicine.
Another, Gergea designed the prestam as a treatment, and he hoped it would help patients with brain and cognitive disorders, such as Alzheimer ’ s in the elderly and speech disorders in children.
But most Nutrobix users now are often completely healthy individuals with no brain abnormality, and do not aim to cure themselves of a disease.
[3]
Smart drug users are also different from any other type of drug users: they are not marginalized groups or young Magna people who dose drugs in dark dens or raucous parties; nootropics are some of the world ’ s finest college students and some of the brightest tech minds in Silicon Valley, the tech heartland of San Francisco.
By taking drugs that are mostly made for people with cognitive disorders as a result of mental illness, these brilliant students and programmers want to enhance their ability to learn, focus and think creatively to become smarter, which seems to be happening under the influence of these drugs.
Phoebe, a history student at a prestigious university in England, describes the impact of nootropics on her in an interview with The Guardian: “These drugs help you work, so you can study longer without distractions.
You feel like going to the library on your own, and you don ’ t even want to take a lunch break.
You look at the clock and it ’ s 7: 00 p.m., but you can still keep going. ”
Johnny, a student at the same university, describes his first experience with drugs: "I had a strange feeling, I remember sitting in the exam and thinking, 'This is terrible!
Oh, my God!
I feel as if I ’ m going to lose consciousness, ” but at the same time I could remember everything, whole paragraphs remembered word for word.
That was great. "[4]
It all sounds really cool, taking a few pills in the morning gives you an incredible ability to work and think.
But, as anyone who has ever taken a drug knows, every drug has side effects that range in severity, from mild things like a headache to symptoms as severe as the disease for which you took it, and additional drugs have to be taken to treat it.
So what are the side effects of entropy?
There aren ’ t enough studies to answer this question, but many people ’ s long-term experience with Nutrobox has never been promising.
Writer and journalist Kate Miller tells her story with those drugs that she started taking after a student in her final year of university, continuing with her after entering her career.
At first, everything seemed great, she found that she could concentrate for long hours and work tirelessly until late at night, and with all this, she was able to maintain a good social life.
But not long after, the ugly face of Nootropics revealed itself to her: Kate became an addict.
In her New York Times article, Kate recounts what she went through: “I was fooling myself when I thought I could stay balanced while taking these drugs, when I thought the benefits outweighed the harm.
I started to increase the doses I was taking, and then, I found myself spending long nights flipping over in bed and falling asleep, my mind racing and my heart beating violently.
When I woke up the next morning, the first thing I did was reach out to take the pills again.
My body started getting used to these drugs, and then I lost their effect, so I started to increase the dose.
I would take it if I found myself yawning after I turned off the alarm.
I turned into a wreck, always angry and lost my ability to connect with the world. ”
Kate reached the point where she found her life was falling apart on all levels, and here came her decision to stop taking those drugs once and for all.
But what no one has told her is that stopping itself will be difficult, as nitrobix, like other drugs, leaves its users at the beginning of quitting defenseless in front of a barrage of painful withdrawal symptoms.
“I found myself sleeping during meetings and I couldn ’ t finish my work before the deadline.
I also began to feel very hungry and began to eat heavily.
This disorder left me with a very fragile and sensitive brain chemistry, and my weight gain and late work only made matters worse.
It was hard for me to understand at the time that what I was going through was withdrawal symptoms; no one had warned me about the side effects of these drugs. ”
Phoebe and Jonny, students who had been helped by Nootropics during the exam period, soon noticed the bad effect on them; Phoebe began to feel severe pain in her stomach, and Jimmy felt that he was becoming too dependent on her for everything, and he ate it every morning without really needing it.
Fortunately, before they went through Kate ’ s bad experience, the Taliban gave up Nutropics altogether.
Even Dave Asbury, an entrepreneur who takes huge amounts of nootropics every morning and founded a company that makes coffee mixed with the drugs, has developed a severe allergy to certain foods that he has been eating normally throughout his life.
In a paper in the journal Clinical Neuroscience, researchers Farid Taleh and Jane Aglotti found that many Nutrobix drugs cause side effects ranging in severity from diarrhea, headaches, dizziness and insomnia, to memory loss, identity disorders and motor system deficiencies.
The research also included a case study of four individuals between the ages of 17 and 28 who were taken to the hospital emergency room after a nervous breakdown. [6] Here, we find ourselves faced with a more important question: Why would people with high levels of intelligence resort to drugs that may add to their intelligence even deeper, but they may also have side effects that no one knows are serious?
[7]
Tim Farris, an entrepreneur and renowned author of human development books, has no real qualms about the long-term side effects of nootropics.
Speaking to CNN, after he started talking about the amount of pressure entrepreneurs are under today, he concluded: “Just like an Olympian who is willing to do anything, even if he reduces his age to five years, to win a gold medal, you ’ ll think about any drugs you take to become smarter. ”
[8]
Jeff Wu, a software engineer who set up a company that specializes in manufacturing nootropics, goes on to say, “Creativity and high mental performance are the only ways you can succeed in Silicon Valley.
I liken tech and finance to professional athletes, so the only way for your team, product or project to be successful is to have a comparative advantage over competitors. ”
It ’ s not just the tech industry, Wu adds: “To become smarter and more productive is to meet modern day standards of success. ”
If some people seem willing to swallow poorly researched drugs without suffering from a real disease just to increase their ability to produce something strange, you ’ ve never heard of the term and the practices that these drugs and many other strange practices include: body hacking, or “biohacking. ”
As a programmer or engineer might look at a computer looking for ways to develop it, biohackers are trying through methods that vary in extremes, from intermittent fasting to injecting themselves with stem cells, to make their bodies and brains better, stronger, healthier.
At first glance, this may not seem like a bad thing, so who wouldn ’ t want to be the best possible version of themselves?
But what ’ s interesting about this is that their desire to develop their bodies and brains stops at the point where these bodies and brains are more productive, and does not go beyond them to other areas of life, where none of the body hackers, for example, thought about creating a drug that by taking it more willing to help others in their distress.
Faced with the large number of people who are willing to take Nutropics to increase their production capacity, neuroscientist Anders Sandberg found in a study that only 9% of people are willing to take a drug that makes them more empathetic or kinder.
This increased use of nootropics and the willingness to manipulate the very composition of the body in order to increase production is itself a symptom of a civilizational disease that envelops our world today: the obsession with success at any cost.
The Guardian ’ s Carol Gadwallar says of this: “In the 1960s, sedatives were known as the little helper of mothers.
Today, however, Futropics is a small aid to capitalism.
“It ’ s just another symptom of a world dominated by competition where everyone is looking for a comparative advantage that puts them above others. ”
[10] Neuroscientist Anjan Chatterjee says: "Today, from the moment of their birth until their death, people only know about running in a rat race.
We are overwhelmed by the feeling that there are a limited number of prizes on the horizon and that everyone is competing for them.
It ’ s hard and you ’ re willing to do anything to win. ”
[11]
In this world governed by machines and numbers, we are also expected to become machines: machines that wake up in the morning and work tirelessly until evening falls, and everything is ultimately governed by numbers.
How successful you are depends on how much you produce each day, which at the end of the month will translate into how much you make.
Your salary or wealth is no longer just a means to provide you with a decent life, but has become a kind of obsession, everyone wants to be successful in a modern culture that values only material values, and defies those who fail the test of making money.
In such a culture, it is not surprising to find people willing to swallow drugs with unknown side effects in order to be better.
Isn ’ t that, in one way or another, what modern culture imposes on us all today, working to burn and losing some of life ’ s simplest pleasures just to live properly and escape the stigma of failure?
The question remains: Is there then a relentless pursuit of success, what kind of happiness?
Or is the summit nothing more than a glittering image of something really empty and cold and lonely?
_ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _
Sources:
1.
I ’ m The Guy Who Created Bulletproof Coffee – This Is My Morning Routine
2.
Nootropic
3.
Under pressure, Silicon Valley workers turn to LSD microdosing
4.
Students used to take drugs to get high.
Now they take them to get higher grades
5.
The Last All-Nighter
6.
Probable Nootropicinduced Psychiatric Adverse Effects: A Series of Four Cases
7.
My smart drugs nightmare
8. smart drugs: what silicon valley is on
9.
Under Pressure: Silicon Valley workers turn to lsd
10.
Students used to take drugs to get high.
Now they take them to get higher grades
11.
Under Pressure: Silicon Valley workers turn to lsd
Source: The Island
About this story
“Narcissism ” is a widespread term, often misused to describe anyone who abuses us.
But in fact, a little bit of narcissism will do you good -- this report looks at the evolution of the concept of narcissism over the past decades.
6 / 10 / 2017
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Approach biohacking with a critical perspective, prioritizing evidence-based methods and specialist consultation to avoid harm.

Biohacking can improve health and well-being, but it's crucial to approach it with caution and a nuanced perspective.