Biohacking, as practiced by individuals like Lepht Anonym, is not supported by reliable scientific data from clinical research, and its methods and techniques are not scientifically validated.

The document discusses a breakthrough in synthetic biology, where researchers have designed a system that performs key functions of living cells, with potential applications in medicine and manufacturing.

The document discusses the field of biopharmaceutical production and evolutionary genomics, focusing on the decoding of genomes and the study of evolution and gene function.

The gene editing technology mentioned in the document is CRISPR-Cas9, which allows researchers to modify genomic DNA at specific target sites.

Biohacking aims to improve human health and overcome physical limits through self-optimization techniques.

Neurofeedback therapy is a biohacking method used to improve mental health, with patients reporting positive results in managing conditions such as ADHD, trauma, and OCD.

A key focus of biohacking is to improve the quality of life by lowering the morbidity rate, as stated by Dr. Claudio Urbani.

"Biohacking involves various methods, including intermittent fasting, hydration, and sleep care, aimed at self-optimization and improving health and well-being."

Biohackers aim to improve the human condition and reduce disease incidence through self-experimentation with biotechnologies.

The biohacker's approach aims to improve human health and well-being by using self-optimization methods, with the goal of living longer and healthier.

The practice of biohacking is viewed as controversial and raises ethical concerns due to its experimental nature and lack of reliable scientific data to support its methods.

Biohacking, as practiced by individuals like Lepht Anonym, is not supported by reliable scientific data from clinical research, and its methods and techniques are not scientifically validated.

Title:

Content: Biohacking is a controversial practice, but Lepht Anonym accepts its risks. More than once he has ended up in the ER, leaving doctors perplexed by inserting chips and even boxes with connectors into his body.

Centuries ago, when a doctor wanted to try a new vaccine or a new drug that he had created … he tested it on himself. Many died while developing new medicines.

Some biohackers they see themselves as those pioneering doctors of the Middle Ages: they test on their own body biotechnologies that aspire to improve the human being, cure diseases, and evolve the human condition, to achieve the desired happiness. And some have also died trying.

The biohacking, also known by the name of DIY biology or DIYbio, has as purpose improve our human condition making nanotechnology, genetic engineering, and technological implants available to everyone. You have more information on this card:

From its origins, Humanity pursues immortality and eternal youth. Biohacking seeks to improve our human condition with cybernetic implants. We explain who biohackers are, and why chips are installed inside the body.

Biohackers implant chips, sensors, machines and other mechanisms with the aim of overcoming physical and intellectual limits.

There is an ethical branch o legal of biohacking that only experiments with implants that do not pose a health hazard, for example chips under the skin.

But another trend is committed to not setting limits, even at the cost of putting your health at risk. Its objective is to defeat all diseases, aging and even death, with the help of technology. Then we will stop being human to become transhumans.

A first step towards posthumanism, where Humanity could dispense with its own body and live eternally as data in a neurological network.

Tips and guide to buy a next-generation sports watch that fits your needs and helps you improve your sports goals.

Within these biohackers, grinders they are the most extreme version. It is the case of Lepht Anonym, a British biohacker that, as he tells us Business Insider, more than 50 chips, antennas and other devices have been implanted in the body.

Read:  You can now install macOS Monterey with new features in Shortcuts, Safari, spatial audio in FaceTime and much more

As only professionals can use anesthesia, all Lepht Anonym implants have been inserted into your body by volunteers, to live. Your goal is “improve our quality of life through technology“.

Lepth explains on his blog that inserts its own chips because “there is no other easy way to do it. I will not wait for someone with a research laboratory to endorse this search.“.

The first chip that this biohacker was implanted under the skin, it allowed pay in stores simply by touching the card reader.

It was also implanted some magnets under the fingers, which detected external sensors to feel the distance between hands and objects. This could help blind people to move without hitting obstacles.

Hackers and the computer world are increasingly present in television fictions. Surely at the moment we can think of a series that deals with these topics, but if you can only think of one or two, we have selected a few about hackers that we find interesting.

His latest experiment, last year, has been his most troublesome. A box several centimeters long, with antennas, USB storage and connectors, was inserted under the arm. All went well until he hit his arm in a taxi, and began to swell. He had to go to the emergency room:

There the doctors told me that I was fatal, that they did not understand why I had put a box in my arm“.

In the end, he gave up: “They kept insisting that I take it off. I let them do it because they discovered that a hole had opened in one corner of the device and a large amount of a viscous substance was coming out“.

After that incident, Lepht Anonym has not updated his blog again.

The biohacking it is a practice that is just beginning. But without a doubt, it will go further. There are already medical biohackers, and the goal is to incorporate this branch of technology into medicine.

Put it in the hands of experts, because people’s health is at stake.

The document discusses a breakthrough in synthetic biology, where researchers have designed a system that performs key functions of living cells, with potential applications in medicine and manufacturing.

Title:

Content: Health · Life
Two Bacteria Create Living Synthetic Cells
Zhang Mengran
September 21, 2022 07: 49 Source: Science and Technology Daily
Researchers at the University of Bristol have taken an important step in synthetic biology by designing a system that performs several key functions of living cells, including generating energy and expressing genes.
The results were published recently in the journal Nature.
In the first 48 hours of "life," the researchers artificially constructed cells even changed from spherical to more natural amoeba-like shapes, suggesting that the primordial cytoskeleton filaments were working.
Scientists previously focused on making artificial cells perform a single function, such as gene expression, enzymatic catalysis or ribozyme activity.
If scientists unlock the secret of artificial cells that can more closely mimic life, it could create a wealth of possibilities in everything from manufacturing to medicine.
To accomplish this latest bottom-up bioengineering feat, the researchers used two bacterial colonies — Escherichia coli and Pseudomonas aeruginosa — as parts.
Mix the two bacteria with empty droplets in a viscous liquid, one trapped inside the droplet and the other trapped on the surface of the droplet.
The researchers broke down the bacterial membrane by soaking the colony in lysozyme and honeybee protein, a polypeptide derived from bee venom, and the bacteria spilled its contents, which were captured by droplets to produce the membrane-coated original cells.
The study demonstrated that these cells are capable of complex processing, such as the production of energy storage molecule ATP through glycolysis, as well as the transcription and translation of genes.
The researchers say that this method of assembling active substances provides an opportunity for the construction of bottom-up symbiotic / synthetic cell structures.
For example, the use of engineered bacteria has the potential to create complex modules for development in the diagnostic and therapeutic areas of synthetic biology, as well as in biomanufacturing and biotechnology.
In the future, this synthetic cell technology could also be used to improve ethanol production for biofuels and food processing.
Combining knowledge based on advanced models of basic biology, researchers can mix and match some structures while redesigning others to build entirely new systems.
Artificial cells can also be programmed to photosynthesize like purple bacteria, or to generate energy from chemicals like sulfate-reducing bacteria.
【 Editor-in-Chief 】
Cells are called the basic structure of life, but they are not “basic. ”
The mechanisms within cells are very complex, and advances in biological technology have allowed humans to adopt bottom-up strategies to try to reconstruct cellular biological processes from the source.
Synthetic biology, also a hot field in recent years, uses engineered organisms to produce what humans want.
This time, the researchers used two bacterial colonies as parts to create some kind of living, functional cell.
Taking advantage of the east wind of synthetic biology, researchers "make everything out of bacteria."
Creating cells not only has practical value, but also helps us understand this basic structure more deeply.
(Editor: Sun Hongli, Yang Di)
Related News

The document discusses the field of biopharmaceutical production and evolutionary genomics, focusing on the decoding of genomes and the study of evolution and gene function.

Title:

Content: • City
• Science and education
SPbU scientists were the first in Russia to receive a Zuckerberg grant: who are they and what will the money of the founder of Facebook be spent on?
Researchers of the Center for Bioinformatics and Algorithmic Biotechnology of St. Petersburg State University were the first in Russia to receive a grant from the Chan-Zuckerberg Initiative Foundation.
At the request of Sobaka.ru editors, they told about themselves, their work, and how they published one of the most cited articles in the history of modern Russian science.
• Bloomicon / Shutterstock
Alla Lapidus
Director of the Center for Bioinformatics and Algorithmic Biotechnology, St. Petersburg State University
Although I am a physicist in my first education, I have always loved biology.
Once my dad, a nuclear physicist, said that without mathematics, biology can not develop, and I felt it.
In 1993, I received a grant from the National Institute of Agricultural Research of France and an invitation to take part in one of the first European genomic projects: decoding the genome of the bacterium Bacillus subtilis, or hay bacillus (from which some antibiotics are obtained).
Then such a science as bioinformatics did not exist, and the genome of this organism was divided between many laboratories, simultaneously inventing methods of its reading, corresponding algorithms and protocols.
The results of this work were published in 1997 in the journal Nature.
“Then such a science as bioinformatics did not exist, and the genome of the organism was divided between many laboratories, simultaneously inventing methods of its reading, appropriate algorithms and protocols ”
Our Center in St. Petersburg was created by the Russian-American scientist Pavel Pevzner at the Academic University in the early 2010s on the wave of mega-grants.
We then moved to SPBU.
Initially, we worked with very specific DNA data isolated from single cells (e.g. bacteria).
This is not easy, because usually for the analysis of the genome, many cells are isolated, from which they receive a lot of DNA and work quietly.
If we need to analyze the genome of a single cell, then a single DNA molecule has to be multiplied by a certain laboratory method in order to be enough to read it.
However, early programs could not process these data, and our laboratory created a special tool for this.
To make it user-friendly, I was invited to St. Petersburg.
I went for six months and stayed for many years.
Over the years of our work in the center, we have gained fame on almost all continents.
We participated in the analysis of coronavirus genomes of patients of the 40th hospital, studied our St. Petersburg strains.
Analyzed data on brain cells, participated in the assembly of the genome of Mycobacterium tuberculosis (also known as Koch's bacillus, the causative agent of tuberculosis).
Speaking about the Chan-Zuckerberg grant, I want to note one unique aspect.
The grant specifically spelled out the condition: in the scientific group applying for the grant, there must be women.
The purpose of this requirement is to support women in science and draw special attention to this topic.
We have girls in the laboratory, and their talent, knowledge, help us conduct research and, in particular, helped to participate in this competition.
• GoodStudio / Shutterstock
Alexey Gurevich
Senior Researcher, Center for Bioinformatics and Algorithmic Biotechnology, St. Petersburg State University
When I was a student, I wasn ’ t going to become a bioinformatician at all, I was going to become a programmer.
However, everything changed in the magistracy.
We had a mandatory practice.
Someone went to Yandex, someone to JetBarins, and I chose a bioinformatics laboratory.
And so it remained in it.
Bioinformatics is a very broad field at the intersection of biology, computer science, mathematics.
One of its notable directions is the decoding of genomes.
The entire DNA of an organism can be represented as a very long string consisting of (in total) four different letters.
The length of the string can be different: in bacteria it is several million, in humans it is about three billion.
This chain cannot be deciphered at a time, so it is cut into pieces, read them and then assembled together.
This work is like putting together a puzzle of millions and even billions of pieces.
It is impossible to do this manually, for this we need special programs that we are in the center and developing.
“This work is like putting together a puzzle of millions and even billions of pieces.
Manually it is impossible to do this, it requires special programs that we are in the center and develop. "
Why do we need this job at all?
From the genome, we can study the evolution of individual species, see how close they are to each other.
Also, individual genes are responsible for certain processes in the body.
It is important to understand which genes are responsible for what in order to effectively fight aging, cancer, and other diseases.
For example, now the scientists of our center are participating in an international project on a new assembly of the human genome.
It was already assembled in the 90s and 2000s, it was a breakthrough, but some parts of the genome remained unread.
Now the task is to read everything from the first letter to the last in all chromosomes.
In addition, in recent years, the focus of our work, including mine, has shifted towards antibiotics.
Now there are more and more bacteria that are resistant to these drugs.
New substances with antibiotic properties are increasingly difficult to find.
And here the help of bioinformatics is important: it is necessary to collect the genomes of microorganisms that can secrete potentially interesting substances, to analyze whether they are able to secrete a fundamentally new antibiotic for us.
• magic pictures / Shutterstock
Andrey Przybelsky
Senior Researcher, Center for Bioinformatics and Algorithmic Biotechnology, St. Petersburg State University
To be honest, I have never been particularly interested in biology.
When I was at the Academic University, there was a laboratory for bioinformatics.
I was offered a job.
I didn ’ t even know that word then, I was skeptical, but I decided that if you don ’ t need to learn a lot of biology, you can try to program algorithms.
Over time, the new field so captured me that it is difficult for me to imagine that I will do anything else.
The most famous development of our center was the SPAdes genomic collection program (it was she who was supported by the Chan-Zuckerberg grant).
We created it to collect the genomes of bacteria, but now it is used around the world, working with the genomic data of viruses, fungi and other organisms.
From the very beginning, we focused not only on the quality of the algorithm (although we did not forget about it!), but also on the ease of use.
As a result, this program is actively used all over the world.
The article, where our algorithm is described, is in the TOP-500 articles in the world by citation for the last 10 years.
This is one of the most cited articles in the recent history of Russian science.
The program has hundreds of thousands of downloads.
“The article, which describes our algorithm, is in the TOP 500 articles in the world for citation in the last 10 years.
This is one of the most cited articles in the recent history of Russian science.
The second tool supported by the grant: QUAST.
This is a program for testing the quality of genomic assembly.
It is slightly less popular, although it is still among the actively downloaded by scientists from around the world.
• GoodStudio / Shutterstock
Anton Korobeinikov
Leading Researcher, Center for Bioinformatics and Algorithmic Biotechnology, St. Petersburg State University
I came to bioinformatics not in the usual way.
In general, I have a thesis on statistics, and I still give lectures on statistical methods.
And yet, in bioinformatics, I see many problems that I could be useful in.
I am the head of the works supported by the Chan-Zuckerberg grant.
The peculiarity of this grant is that it is aimed not at future scientific discoveries, but at supporting and developing existing open source programs in the field of bioinformatics and biomedicine.
Our SPAdes genomic assembly software and QUAST genomic assembly quality analysis tool are just such.
They are completely free: that is, any scientist, researcher, doctor, any reader of Sobaka.ru can download the program and adapt it to their needs.
“Any scientist, researcher, doctor, any reader of Sobaka.ru can download the program and adapt it to their needs ”
What the money will go for: over the years of using SPAdes, we have accumulated a lot of experience in developing methods for assembling genomes.
However, now there is a change of generations of technologies for reading genomes: the data is becoming completely different.
And we want to adapt our design to them.
To turn it into a set of modules that any scientist, even not very well versed in software code, could quickly and easily adapt to their tasks.
In this way, we will lower the threshold for entering bioinformatics research and, hopefully, contribute to its development around the world.
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The gene editing technology mentioned in the document is CRISPR-Cas9, which allows researchers to modify genomic DNA at specific target sites.

Title:

Content: ABOVE: Researchers investigated the inadvertent genotoxicity that arises from CRISPR-Cas9 gene editing in T cells and stumbled upon a solution. ©iStock, LadadikArt

Thanks to gene editing tools such as CRISPR-Cas technologies, researchers can now insert, delete, or replace genomic DNA at specific target sites to inactivate genes, acquire new traits, and correct genetic mutations.1 The well known CRISPR-Cas9 system relies on a guide RNA that directs the Cas9 enzyme to a desired DNA sequence, which the enzyme cuts, forming double-strand breaks (DSB). One important application for CRISPR-Cas9 technology is potentially boosting the immune response in patients with cancer by engineering autologous T cells to target and destroy tumor cells.2

While CRISPR-Cas9 genome editing enables advanced T cell therapies, scientists have safety concerns.3 Improper DSB repair can lead to the loss of Cas9-targeted chromosomes, but these unintended effects remain largely unexplored. “There were a couple of papers in the field that showcased this [chromosome loss], but nothing that was very comprehensive,” said Connor Tsuchida from the University of California, Berkley and founder of the biotech company Stealth Startup. In his recently published paper in Cell, Tsuchida and his colleagues reported how widespread the Cas9-induced chromosomal loss was when editing human T cells.4

To investigate how Cas9 gene editing affected T cells, the researchers targeted the first exon of the TRAC locus, which encodes the T cell receptor on chromosome 14. As expected, DNA sequencing results showed that the intended locus was edited. However, when the researchers analyzed the cells’ transcriptome-wide single-cell RNA sequencing (scRNA-seq) data, they detected reduced gene dosage on chromosome 14 and found that five to 20 percent of the T cells exhibited partial or whole chromosome loss.

To further look at the chromosome loss phenomenon, Tsuchida and his colleagues used CRISPR-Cas9 to edit multiple genes on every somatic chromosome. They found that chromosome loss occurred for almost 90 percent of all targets, no matter where the edit occured. Taken together, these results suggested that chromosome loss from T cell genome editing is a general feature of Cas9 editing across target sites.

The researchers then assessed the consequences of Cas9-induced chromosome loss. They monitored edited cells in vitro for two to three weeks, a timeframe similar to current clinical adoptive T cell therapy manufacturing protocols, and found that although these cells survived, they had detectable levels of chromosome loss throughout and showed reduced proliferation and fitness. Therefore, compromised T cells with Cas9-induced chromosome loss could persist long enough during cell therapy manufacturing to end up in patients. The researchers also saw significant overexpression of two gene modules in these cells: the p53 DNA damage response and general apoptosis pathways.

The researchers wondered if they could find evidence of engineered T cell chromosome loss in existing clinical trials.2 They investigated scRNA-seq data throughout a trial completed in 2020, where patients with advanced, refractory cancer received CRISPR-Cas9-edited T cells, called NY-ESO-1 transduced CRISPR 3X edited cells (NYCE cells). “We didn't find any [chromosome loss] at all, which was surprising for us,” said Tsuchida.

After investigating several factors that may explain this discrepancy, Tsuchida and his colleagues found a key difference in the clinical trial’s T cell engineering protocol. In Tsuchida’s study, and in nearly all other clinical trials testing genome-edited T cells, CRISPR editing occurred after T cell activation and stimulation. In contrast, the NYCE cells were edited before activation, which may have decreased chromosome loss.

“The important part is that [Tsuchida’s team] demonstrated a way to mitigate unintended chromosome loss by changing the protocol,”  said Ayal Hendel, a CRISPR editing researcher from Bar-Ilan University, who was not involved with this study. “They demonstrated that if you first take the T cells, induce edits, and only later start with the activation … you get less chromosome loss. This is the main new aspect of this paper.”

To further understand the difference between these two protocols, the researchers looked at TP53 expression. This gene encodes the p53 protein involved in the DNA damage response and T cell activation. They found that TP53 expression after CRISPR-Cas9 editing inversely correlated with rates of chromosome loss. The researchers speculated that when engineering NYCE cells, high TP53 expression may have favored cells with intact chromosomes. Modulating p53 while following the NYCE protocol may help protect CRISPR-engineered cells against aneuploidy. “[Treating cells] with small molecules that either activate p53 or inactivate an inhibitor of p53 before genome editing … may [offer] transient protection,” Tsuchida hypothesized. “It's something we are interested in getting into.”

References:

  1. Xu Y, et al. CRISPR-Cas systems: Overview, innovations and applications in human disease research and gene therapy. Comput Struct Biotechnol J. 2020;18:2401-2415.
  2. Stadtmauer EA, et al. CRISPR-engineered T cells in patients with refractory cancer. Science. 2020;367(6481):eaba7365.
  3. Nahmad AD, et al. Frequent aneuploidy in primary human T cells after CRISPR-Cas9 cleavage. Nat Biotechnol. 2022;40(12):1807-1813.
  4.  Tsuchida CA, et al. Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells. Cell. 2023;186(21):4567-4582.e20.

Biohacking aims to improve human health and overcome physical limits through self-optimization techniques.

Neurofeedback therapy is a biohacking method used to improve mental health, with patients reporting positive results in managing conditions such as ADHD, trauma, and OCD.

Title:

Content: NewsLocal NewsSummit County

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'It saved my life,' ADHD, trauma, OCD patients turn to neurofeedback therapy

Posted at 8:18 AM, Apr 05, 2024
and last updated 2024-04-05 08:18:12-04

CUYAHOGA FALLS, Ohio — Cracking the code to wellness is now costing Americans $1.8 trillion annually.

For the average American, that breaks down to more than $5,300 per year.

Those numbers come from the Global Wellness Summit's 2024 trends report.

The report also shows that the global wellness economy, which generated $5.6 trillion in 2022, will continue to surge and reach $8.5 trillion within the next three years.

A driver of those staggering stats is ‘biohacking,’ which is the term for do-it-yourself biology.

It has generated 951 million views on TikTok and over on Google, there's been a 900% increase in searches for ‘biohacking.’

"The way that i like to describe it is using what we know about biology to help us become better versions of ourselves," said Britney Cirillo with Alternative Therapeutics.

‘Biohacking’ can be anything from using a smartwatch to track our heart rate to jumping in an ice bath and neuro-feedback therapy.

The idea behind neuro-feedback therapy is that we can essentially re-train our brain to tackle mental health issues like depression, anxiety, trauma, and OCD, which Emily Dean suffered from for about a decade.

"Was pretty afraid to even leave my house alone. At my worst, I was unable to care for my physical health," said Dean.

Dean ultimately needed to check into the hospital as her mental health declined.

After being discharged, she discovered neurofeedback therapy.

"It completely changed my life," said Dean.

Dean said the sessions at Alternative Therapeutics in Cuyahoga Falls provided relief that medications and traditional therapies could not.

"We're not your average counseling practice," said Cirillo.

Cirillo uses neurofeedback therapy to balance electrical activity in a patient's brain, regulating delta, theta, alpha, and beta levels.

"If any of those brainwaves are being overproduced or underproduced, that will correlate with symptoms that the client is experiencing," said Cirillo.

The goal is to essentially retrain the brain using operant conditioning, a learning process in which voluntary behaviors are rewarded.

"We tell the brain to do a certain thing when it does that certain thing, they're rewarded instantly by that video game that they're playing," Cirillo.

I was so interested in how it works that Cirillo gave me a taste of a typical session.

My goal was to keep the flames of a fire burning bright and the sound of the crackling strong while playing a game on a tablet.

Cirillo was checking to make sure my brain was in an ideal zone.

I only sat there with the tablet for a short time, but a typical therapy session lasts about 20 minutes.

"And so, with more and more practice, the brain starts to recognize what it's supposed to do and it reinforces that pathway, strengthens it to the point that that's their new normal," said Cirillo.

Despite gaining popularity during this ‘biohacking craze,’ neurofeedback therapy is still considered experimental.

"I think it's an interesting phenomenon," said Dr. Robert Lufkin with the USC School of Medicine.

Lufkin said regulating the brain could give people better outcomes when it comes to their mental health.

"I think in my opinion, this can have beneficial effects on an individual," said Lufkin.

Lufkin said regardless of what form of ‘biohacking’ people choose, it's shifting the balance of the doctor-patient relationship.

"It's certainly exploding in recent years, and I think it reflects the fact that all of us as, as patients are taking control of our own health," said Lufkin.

Dean is beyond grateful she gained control.

"Neurofeedback therapy and Alternative Therapeutics saved my life," said Dean.

After completing 20 sessions five years ago, Dean has been able to maintain her progress with a few booster sessions, along with some tools to help her navigate the world.

A world that, for years, Dean navigated with crippling fear.

"Before neurofeedback I was afraid to go to the grocery store alone. Last year, I went to California alone. That is something that I never thought would be possible for me," said Dean.

With insurance companies still considering neurofeedback therapy experimental it is not covered.

However, Cirillo said many of her clients have success when they submit for out of network reimbursement.

On average, people will need about 20 sessions to get the end results they're looking for.

A key focus of biohacking is to improve the quality of life by lowering the morbidity rate, as stated by Dr. Claudio Urbani.

Title:

Content: Home » biohacking, reprogramming mind and body to live better

biohacking, reprogramming mind and body to live better

by admin

It’s called “biohacking” and it comes from Silicon Valley. Listen: The long life diet: the longevity formula is calorie restriction …

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It’s called “biohacking” and comes from Silicon Valley.

A relatively new word that comes from the union of “biology” and “hacker” and indicates the attempt to positively influence the functioning of the organism, by hacking, ie trying to “force”, one’s genetic heritage. A strategy to live better and longer launched years ago by Californian top managers and which then spread throughout the world. How to upgrade the “operating system” of the human body? No manipulation, here we are talking about “reprogramming” and new lifestyles. “Our genetic heritage has enormous unexpressed potential that can be activated,” he explains Fabio Piccinidoctor and psychoanalyst, researcher of Food Sciences of theMarche Polytechnic University, author of the book “Biohacking Techniques: how to optimize metabolism to increase health and longevity”. “Biohacking aims to activate epigenetic modifications by awakening dormant genes to enhance the body’s resources.” While genetics studies the structure of DNA, epigenetics the way genes express themselves, i.e. how much they are turned on or off. “We’re talking about a set of strategies that aim to strengthen the body from a physical and mental point of view, first of all through nutrition, sleep quality, physical activity, cognitive stimulation”. One of the pillars of biohacking and the intermittent fasting, Piccini adds, which plans to concentrate the diet in a precise time span of the day (to be followed always under medical supervision). «But it is equally important to take care of sleep, we know very well that sleep debt accelerates aging and that 30-40 percent of people sleep too little. Just as it is essential to check thehydration. Physical training must also be intermittent, with recovery periods in place to allow the muscle layers to rebuild. And then, you have to keep learning something at any age, another pillar of biohacking: studying music or a new language, for example, to counteract cognitive degeneration”.

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THE QUALITY OF LIFE

Sandra Milo is one of the supporters of this well-being and longevity strategy. «I’m lucky, at 90 I’m in full health and I still have a great desire to enjoy life. I don’t know if it’s a matter of genetics, nor do I think there is a “magic formula” of longevity, but I have certainly always been careful to lead a healthy life. There is nothing more beautiful than reaching old age with a smile and in full autonomy », says the actress who baptized the first Biohacking Suite in Rome. “Our mission is not so much to lengthen life but to improve its quality by lowering the rate of morbidity,” explains Dr. Claudio Urbani, specialist in regenerative medicine, neuroscience and stress therapy, head of the longevity center Umb. «Biohacking aims to modify dormant functional responses from non-use, from muscular or cardiovascular function to flexibility. It is about regaining possession of the body and the mind-body axis, starting with stress management». Diagnosing your own state of “aging” involves a series of tests. «The measurement of oxidative stress which measures the quantity of free radicals and indicates any inflammatory states, plethysmography to evaluate the functionality of the microcirculation of the legs, impedancemetry to study body composition, fat and lean mass, nutritional status and hydration level. And only after the check is a tailor-made program created for each person. Among the suggested therapies, there is also that of the cold which stimulates the metabolism and reduces inflammation ».

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According to the studies, how does intermittent fasting help?

"Biohacking involves various methods, including intermittent fasting, hydration, and sleep care, aimed at self-optimization and improving health and well-being."

According to the studies, how does intermittent fasting help?

Biohackers aim to improve the human condition and reduce disease incidence through self-experimentation with biotechnologies.

The biohacker's approach aims to improve human health and well-being by using self-optimization methods, with the goal of living longer and healthier.

According to the studies, how does intermittent fasting help?

The practice of biohacking is viewed as controversial and raises ethical concerns due to its experimental nature and lack of reliable scientific data to support its methods.